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Genes within 1Mb (chr1:64689117:CAT:C):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 -378637 sc-eQTL 9.10e-01 -0.00982 0.0872 0.1 B L1
ENSG00000213625 LEPROT -731470 sc-eQTL 3.31e-02 -0.236 0.11 0.1 B L1
ENSG00000158966 CACHD1 218988 sc-eQTL 6.47e-01 -0.037 0.0806 0.1 CD4T L1
ENSG00000162434 JAK1 -378637 sc-eQTL 8.02e-01 -0.0212 0.0845 0.1 CD4T L1
ENSG00000213625 LEPROT -731470 sc-eQTL 1.02e-01 -0.216 0.131 0.1 CD4T L1
ENSG00000116678 LEPR -731535 sc-eQTL 6.85e-01 -0.0569 0.14 0.1 CD8T L1
ENSG00000158966 CACHD1 218988 sc-eQTL 4.65e-01 -0.0503 0.0688 0.1 CD8T L1
ENSG00000162434 JAK1 -378637 sc-eQTL 5.89e-01 0.0587 0.108 0.1 CD8T L1
ENSG00000213625 LEPROT -731470 sc-eQTL 1.28e-01 -0.219 0.143 0.1 CD8T L1
ENSG00000116678 LEPR -731535 sc-eQTL 3.77e-01 -0.123 0.139 0.101 DC L1
ENSG00000162433 AK4 -458432 sc-eQTL 6.79e-01 0.0486 0.117 0.101 DC L1
ENSG00000162434 JAK1 -378637 sc-eQTL 2.69e-01 0.108 0.0974 0.101 DC L1
ENSG00000162437 RAVER2 -55978 sc-eQTL 9.75e-01 -0.00386 0.125 0.101 DC L1
ENSG00000213625 LEPROT -731470 sc-eQTL 4.08e-01 -0.115 0.138 0.101 DC L1
ENSG00000116678 LEPR -731535 sc-eQTL 1.69e-01 -0.192 0.139 0.1 Mono L1
ENSG00000162433 AK4 -458432 sc-eQTL 3.43e-03 0.37 0.125 0.1 Mono L1
ENSG00000162434 JAK1 -378637 sc-eQTL 3.94e-01 -0.0776 0.0908 0.1 Mono L1
ENSG00000213625 LEPROT -731470 sc-eQTL 8.67e-01 0.0151 0.0901 0.1 Mono L1
ENSG00000116678 LEPR -731535 sc-eQTL 7.95e-01 0.0348 0.134 0.101 NK L1
ENSG00000162434 JAK1 -378637 sc-eQTL 3.49e-01 -0.0593 0.0632 0.101 NK L1
ENSG00000213625 LEPROT -731470 sc-eQTL 8.16e-01 0.0337 0.145 0.101 NK L1
ENSG00000162434 JAK1 -378637 sc-eQTL 5.19e-02 -0.178 0.0908 0.1 Other_T L1
ENSG00000162437 RAVER2 -55978 sc-eQTL 1.31e-01 0.201 0.132 0.1 Other_T L1
ENSG00000213625 LEPROT -731470 sc-eQTL 9.01e-01 -0.018 0.144 0.1 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 -378637 sc-eQTL 7.02e-02 0.284 0.156 0.094 B_Activated L2
ENSG00000213625 LEPROT -731470 sc-eQTL 1.00e+00 -1e-05 0.165 0.094 B_Activated L2
ENSG00000162434 JAK1 -378637 sc-eQTL 8.71e-01 -0.02 0.123 0.101 B_Intermediate L2
ENSG00000213625 LEPROT -731470 sc-eQTL 9.79e-01 -0.00378 0.144 0.101 B_Intermediate L2
ENSG00000162434 JAK1 -378637 sc-eQTL 7.49e-01 -0.0398 0.124 0.099 B_Memory L2
ENSG00000213625 LEPROT -731470 sc-eQTL 8.05e-02 -0.252 0.144 0.099 B_Memory L2
ENSG00000162434 JAK1 -378637 sc-eQTL 9.21e-01 0.011 0.111 0.1 B_Naive1 L2
ENSG00000213625 LEPROT -731470 sc-eQTL 6.35e-01 -0.0685 0.144 0.1 B_Naive1 L2
ENSG00000162434 JAK1 -378637 sc-eQTL 2.97e-01 0.119 0.114 0.099 B_Naive2 L2
ENSG00000213625 LEPROT -731470 sc-eQTL 5.73e-03 -0.379 0.136 0.099 B_Naive2 L2
ENSG00000158966 CACHD1 218988 sc-eQTL 2.73e-01 -0.0574 0.0523 0.107 CD4_CTL L2
ENSG00000162434 JAK1 -378637 sc-eQTL 4.10e-02 -0.263 0.128 0.107 CD4_CTL L2
ENSG00000213625 LEPROT -731470 sc-eQTL 7.07e-01 0.0558 0.149 0.107 CD4_CTL L2
ENSG00000158966 CACHD1 218988 sc-eQTL 5.30e-01 -0.0506 0.0805 0.1 CD4_Naive L2
ENSG00000162434 JAK1 -378637 sc-eQTL 6.46e-01 0.0378 0.0822 0.1 CD4_Naive L2
ENSG00000213625 LEPROT -731470 sc-eQTL 3.99e-02 -0.273 0.132 0.1 CD4_Naive L2
ENSG00000158966 CACHD1 218988 sc-eQTL 1.83e-02 0.267 0.112 0.1 CD4_TCM L2
ENSG00000162434 JAK1 -378637 sc-eQTL 6.46e-01 -0.0428 0.0931 0.1 CD4_TCM L2
ENSG00000213625 LEPROT -731470 sc-eQTL 6.91e-01 -0.0538 0.135 0.1 CD4_TCM L2
ENSG00000158966 CACHD1 218988 sc-eQTL 5.25e-01 -0.0556 0.0872 0.1 CD4_TEM L2
ENSG00000162434 JAK1 -378637 sc-eQTL 9.41e-01 -0.00915 0.124 0.1 CD4_TEM L2
ENSG00000213625 LEPROT -731470 sc-eQTL 9.94e-01 -0.00109 0.147 0.1 CD4_TEM L2
ENSG00000116678 LEPR -731535 sc-eQTL 6.16e-01 0.0691 0.138 0.1 CD8_CTL L2
ENSG00000158966 CACHD1 218988 sc-eQTL 7.14e-01 0.0227 0.062 0.1 CD8_CTL L2
ENSG00000162434 JAK1 -378637 sc-eQTL 3.64e-01 0.105 0.116 0.1 CD8_CTL L2
ENSG00000213625 LEPROT -731470 sc-eQTL 2.01e-01 -0.181 0.141 0.1 CD8_CTL L2
ENSG00000116678 LEPR -731535 sc-eQTL 8.86e-01 0.0197 0.137 0.1 CD8_Naive L2
ENSG00000158966 CACHD1 218988 sc-eQTL 4.29e-01 -0.0752 0.0949 0.1 CD8_Naive L2
ENSG00000162434 JAK1 -378637 sc-eQTL 4.20e-01 0.0923 0.114 0.1 CD8_Naive L2
ENSG00000213625 LEPROT -731470 sc-eQTL 3.92e-01 -0.12 0.14 0.1 CD8_Naive L2
ENSG00000116678 LEPR -731535 sc-eQTL 4.30e-01 -0.107 0.136 0.102 CD8_TCM L2
ENSG00000158966 CACHD1 218988 sc-eQTL 3.21e-01 -0.0728 0.0731 0.102 CD8_TCM L2
ENSG00000162434 JAK1 -378637 sc-eQTL 6.40e-01 0.0552 0.118 0.102 CD8_TCM L2
ENSG00000213625 LEPROT -731470 sc-eQTL 8.93e-01 0.0198 0.147 0.102 CD8_TCM L2
ENSG00000116678 LEPR -731535 sc-eQTL 9.59e-01 0.0063 0.124 0.105 CD8_TEM L2
ENSG00000158966 CACHD1 218988 sc-eQTL 8.10e-05 0.115 0.0285 0.105 CD8_TEM L2
ENSG00000162434 JAK1 -378637 sc-eQTL 9.13e-01 -0.0153 0.14 0.105 CD8_TEM L2
ENSG00000213625 LEPROT -731470 sc-eQTL 5.28e-01 -0.0912 0.144 0.105 CD8_TEM L2
ENSG00000162434 JAK1 -378637 sc-eQTL 2.16e-01 -0.153 0.124 0.102 MAIT L2
ENSG00000162437 RAVER2 -55978 sc-eQTL 8.72e-01 -0.0213 0.132 0.102 MAIT L2
ENSG00000213625 LEPROT -731470 sc-eQTL 8.88e-01 -0.0202 0.143 0.102 MAIT L2
ENSG00000116678 LEPR -731535 sc-eQTL 2.82e-01 -0.144 0.134 0.104 NK_CD56bright L2
ENSG00000162434 JAK1 -378637 sc-eQTL 7.71e-01 0.0268 0.0917 0.104 NK_CD56bright L2
ENSG00000213625 LEPROT -731470 sc-eQTL 2.88e-01 0.16 0.15 0.104 NK_CD56bright L2
ENSG00000116678 LEPR -731535 sc-eQTL 6.31e-01 0.0678 0.141 0.101 NK_CD56dim L2
ENSG00000162434 JAK1 -378637 sc-eQTL 2.17e-01 -0.091 0.0735 0.101 NK_CD56dim L2
ENSG00000213625 LEPROT -731470 sc-eQTL 8.12e-01 0.0355 0.149 0.101 NK_CD56dim L2
ENSG00000116678 LEPR -731535 sc-eQTL 8.61e-01 -0.0219 0.125 0.098 NK_HLA L2
ENSG00000162434 JAK1 -378637 sc-eQTL 9.59e-01 0.00505 0.0977 0.098 NK_HLA L2
ENSG00000213625 LEPROT -731470 sc-eQTL 8.52e-01 0.0284 0.151 0.098 NK_HLA L2
ENSG00000116678 LEPR -731535 sc-eQTL 7.02e-01 0.0521 0.136 0.101 NK_cytokine L2
ENSG00000162434 JAK1 -378637 sc-eQTL 6.18e-01 -0.0395 0.0792 0.101 NK_cytokine L2
ENSG00000213625 LEPROT -731470 sc-eQTL 5.73e-01 -0.0813 0.144 0.101 NK_cytokine L2
ENSG00000162434 JAK1 -378637 sc-eQTL 8.20e-01 0.0315 0.138 0.078 PB L2
ENSG00000213625 LEPROT -731470 sc-eQTL 4.56e-01 -0.145 0.193 0.078 PB L2
ENSG00000162434 JAK1 -378637 sc-eQTL 8.68e-02 -0.16 0.0932 0.102 Pro_T L2
ENSG00000162437 RAVER2 -55978 sc-eQTL 2.79e-01 0.134 0.124 0.102 Pro_T L2
ENSG00000213625 LEPROT -731470 sc-eQTL 2.70e-01 -0.161 0.146 0.102 Pro_T L2
ENSG00000158966 CACHD1 218988 sc-eQTL 5.59e-01 0.0643 0.11 0.1 Treg L2
ENSG00000162434 JAK1 -378637 sc-eQTL 3.98e-01 -0.0992 0.117 0.1 Treg L2
ENSG00000213625 LEPROT -731470 sc-eQTL 2.82e-01 -0.164 0.152 0.1 Treg L2
ENSG00000116678 LEPR -731535 sc-eQTL 8.62e-01 -0.0255 0.146 0.102 cDC L2
ENSG00000162433 AK4 -458432 sc-eQTL 1.64e-01 0.18 0.129 0.102 cDC L2
ENSG00000162434 JAK1 -378637 sc-eQTL 4.80e-01 -0.0852 0.121 0.102 cDC L2
ENSG00000162437 RAVER2 -55978 sc-eQTL 7.80e-01 0.0371 0.133 0.102 cDC L2
ENSG00000213625 LEPROT -731470 sc-eQTL 3.12e-01 -0.149 0.147 0.102 cDC L2
ENSG00000116678 LEPR -731535 sc-eQTL 9.22e-01 0.0139 0.142 0.1 cMono_IL1B L2
ENSG00000162433 AK4 -458432 sc-eQTL 1.12e-02 0.329 0.128 0.1 cMono_IL1B L2
ENSG00000162434 JAK1 -378637 sc-eQTL 1.41e-01 -0.175 0.118 0.1 cMono_IL1B L2
ENSG00000213625 LEPROT -731470 sc-eQTL 6.35e-01 -0.0456 0.0958 0.1 cMono_IL1B L2
ENSG00000116678 LEPR -731535 sc-eQTL 5.58e-01 -0.0835 0.142 0.1 cMono_S100A L2
ENSG00000162433 AK4 -458432 sc-eQTL 9.10e-02 0.228 0.134 0.1 cMono_S100A L2
ENSG00000162434 JAK1 -378637 sc-eQTL 8.70e-01 -0.0204 0.125 0.1 cMono_S100A L2
ENSG00000213625 LEPROT -731470 sc-eQTL 6.31e-01 0.056 0.116 0.1 cMono_S100A L2
ENSG00000162434 JAK1 -378637 sc-eQTL 1.41e-01 -0.238 0.161 0.124 gdT L2
ENSG00000162437 RAVER2 -55978 sc-eQTL 2.05e-01 0.18 0.142 0.124 gdT L2
ENSG00000213625 LEPROT -731470 sc-eQTL 9.05e-01 -0.0204 0.171 0.124 gdT L2
ENSG00000116678 LEPR -731535 sc-eQTL 7.31e-01 -0.0488 0.142 0.096 intMono L2
ENSG00000162433 AK4 -458432 sc-eQTL 5.25e-01 0.0849 0.133 0.096 intMono L2
ENSG00000162434 JAK1 -378637 sc-eQTL 8.59e-01 0.022 0.123 0.096 intMono L2
ENSG00000213625 LEPROT -731470 sc-eQTL 7.01e-01 -0.0456 0.119 0.096 intMono L2
ENSG00000116678 LEPR -731535 sc-eQTL 4.30e-01 -0.104 0.132 0.104 ncMono L2
ENSG00000162433 AK4 -458432 sc-eQTL 9.61e-01 0.00572 0.118 0.104 ncMono L2
ENSG00000162434 JAK1 -378637 sc-eQTL 3.73e-01 -0.085 0.0952 0.104 ncMono L2
ENSG00000213625 LEPROT -731470 sc-eQTL 6.99e-01 -0.0524 0.135 0.104 ncMono L2
ENSG00000116678 LEPR -731535 sc-eQTL 8.06e-02 -0.271 0.154 0.096 pDC L2
ENSG00000162433 AK4 -458432 sc-eQTL 7.36e-01 0.0343 0.101 0.096 pDC L2
ENSG00000162434 JAK1 -378637 sc-eQTL 4.80e-01 0.0958 0.135 0.096 pDC L2
ENSG00000162437 RAVER2 -55978 sc-eQTL 6.78e-01 0.0635 0.153 0.096 pDC L2
ENSG00000213625 LEPROT -731470 sc-eQTL 3.83e-01 0.147 0.168 0.096 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 -378637 sc-eQTL 3.96e-01 -0.0927 0.109 0.1 B_Memory LOneK1K
ENSG00000213625 LEPROT -731470 sc-eQTL 2.83e-01 -0.151 0.14 0.1 B_Memory LOneK1K
ENSG00000162434 JAK1 -378637 sc-eQTL 8.09e-01 0.0258 0.107 0.1 B_Naive LOneK1K
ENSG00000213625 LEPROT -731470 sc-eQTL 5.67e-02 -0.256 0.134 0.1 B_Naive LOneK1K
ENSG00000116678 LEPR -731535 sc-eQTL 5.86e-01 -0.076 0.139 0.1 CD14_Mono LOneK1K
ENSG00000162433 AK4 -458432 sc-eQTL 1.30e-03 0.424 0.13 0.1 CD14_Mono LOneK1K
ENSG00000162434 JAK1 -378637 sc-eQTL 4.41e-01 -0.086 0.111 0.1 CD14_Mono LOneK1K
ENSG00000213625 LEPROT -731470 sc-eQTL 9.19e-01 -0.00954 0.0935 0.1 CD14_Mono LOneK1K
ENSG00000116678 LEPR -731535 sc-eQTL 2.55e-01 -0.156 0.136 0.101 CD16_Mono LOneK1K
ENSG00000162433 AK4 -458432 sc-eQTL 7.27e-01 -0.0432 0.124 0.101 CD16_Mono LOneK1K
ENSG00000162434 JAK1 -378637 sc-eQTL 8.58e-01 -0.0149 0.0833 0.101 CD16_Mono LOneK1K
ENSG00000213625 LEPROT -731470 sc-eQTL 6.52e-01 -0.0524 0.116 0.101 CD16_Mono LOneK1K
ENSG00000116678 LEPR -731535 sc-eQTL 5.69e-01 0.079 0.138 0.101 NK_CD56dim LOneK1K
ENSG00000162434 JAK1 -378637 sc-eQTL 2.64e-01 -0.0725 0.0647 0.101 NK_CD56dim LOneK1K
ENSG00000213625 LEPROT -731470 sc-eQTL 8.00e-01 -0.0364 0.144 0.101 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000116678 LEPR -731535 eQTL 0.0474 -0.0748 0.0377 0.0 0.0 0.108
ENSG00000162437 RAVER2 -55978 eQTL 0.0188 0.0856 0.0364 0.0 0.0 0.108
ENSG00000233877 AL606517.1 -252862 eQTL 0.0259 -0.117 0.0524 0.0 0.0 0.108

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000116678 LEPR -731535 3.07e-07 1.25e-07 5.93e-08 1.82e-07 8.83e-08 9.91e-08 1.99e-07 5.21e-08 1.45e-07 4.74e-08 1.6e-07 7.75e-08 1.52e-07 7.13e-08 5.99e-08 7.53e-08 3.94e-08 1.21e-07 7.09e-08 3.88e-08 1.22e-07 1.26e-07 1.69e-07 4.26e-08 1.55e-07 1.14e-07 1.06e-07 9.57e-08 1.23e-07 9.49e-08 9.91e-08 3.52e-08 3.26e-08 8.68e-08 8.93e-08 3.97e-08 4.95e-08 9.25e-08 7.2e-08 3.59e-08 3.25e-08 1.33e-07 5.27e-08 1.74e-07 8.79e-08 1.86e-08 1.21e-07 4.2e-09 4.85e-08
ENSG00000233877 AL606517.1 -252862 3.53e-06 2.61e-06 8.15e-07 1.28e-06 4.39e-07 9.27e-07 2.43e-06 2.71e-07 2.22e-06 8.15e-07 2.07e-06 1.14e-06 3.48e-06 1.43e-06 8.95e-07 1.7e-06 1.06e-06 2.23e-06 1.48e-06 6.97e-07 1.81e-06 3.35e-06 3.38e-06 7.1e-07 4.08e-06 1.37e-06 1.05e-06 1.01e-06 4.09e-06 1.61e-06 7.74e-07 6.42e-08 2e-07 6.19e-07 5.25e-07 4.82e-07 1.11e-07 2.73e-07 4.94e-07 3.21e-07 2.11e-07 5.65e-06 5.88e-07 1.13e-06 3.43e-07 3.96e-07 7.76e-07 1.43e-07 1.97e-07