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Genes within 1Mb (chr6:134300864:C:T):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000028839 TBPL1 348694 sc-eQTL 3.84e-01 -0.0797 0.0913 0.297 B L1
ENSG00000112339 HBS1L -802192 sc-eQTL 4.82e-01 0.0394 0.056 0.297 B L1
ENSG00000118515 SGK1 -17248 sc-eQTL 4.63e-03 -0.179 0.0627 0.297 B L1
ENSG00000028839 TBPL1 348694 sc-eQTL 1.31e-01 0.1 0.066 0.297 CD4T L1
ENSG00000112339 HBS1L -802192 sc-eQTL 2.49e-01 0.0555 0.048 0.297 CD4T L1
ENSG00000118513 MYB -880444 sc-eQTL 2.87e-01 -0.0567 0.0531 0.297 CD4T L1
ENSG00000118515 SGK1 -17248 sc-eQTL 1.61e-03 -0.17 0.0533 0.297 CD4T L1
ENSG00000028839 TBPL1 348694 sc-eQTL 5.82e-01 0.0362 0.0657 0.297 CD8T L1
ENSG00000112339 HBS1L -802192 sc-eQTL 5.48e-01 -0.0341 0.0566 0.297 CD8T L1
ENSG00000118513 MYB -880444 sc-eQTL 5.61e-01 -0.0365 0.0627 0.297 CD8T L1
ENSG00000118515 SGK1 -17248 sc-eQTL 2.13e-02 -0.0966 0.0416 0.297 CD8T L1
ENSG00000028839 TBPL1 348694 sc-eQTL 4.52e-01 -0.0777 0.103 0.291 DC L1
ENSG00000112339 HBS1L -802192 sc-eQTL 8.00e-02 0.157 0.0894 0.291 DC L1
ENSG00000118513 MYB -880444 sc-eQTL 8.33e-01 -0.0138 0.0655 0.291 DC L1
ENSG00000118515 SGK1 -17248 sc-eQTL 9.23e-03 -0.154 0.0588 0.291 DC L1
ENSG00000286887 AL355881.1 4563 sc-eQTL 1.90e-02 -0.216 0.0912 0.291 DC L1
ENSG00000028839 TBPL1 348694 sc-eQTL 3.66e-01 0.0627 0.0692 0.297 Mono L1
ENSG00000112339 HBS1L -802192 sc-eQTL 2.65e-01 0.0766 0.0686 0.297 Mono L1
ENSG00000118515 SGK1 -17248 sc-eQTL 7.67e-08 -0.266 0.0478 0.297 Mono L1
ENSG00000286887 AL355881.1 4563 sc-eQTL 1.29e-06 -0.332 0.0667 0.297 Mono L1
ENSG00000028839 TBPL1 348694 sc-eQTL 9.24e-01 0.00725 0.0761 0.298 NK L1
ENSG00000112339 HBS1L -802192 sc-eQTL 8.21e-01 -0.0141 0.0623 0.298 NK L1
ENSG00000118515 SGK1 -17248 sc-eQTL 5.85e-03 -0.183 0.0658 0.298 NK L1
ENSG00000028839 TBPL1 348694 sc-eQTL 8.05e-02 0.156 0.0887 0.297 Other_T L1
ENSG00000112339 HBS1L -802192 sc-eQTL 6.08e-01 0.0304 0.0591 0.297 Other_T L1
ENSG00000118515 SGK1 -17248 sc-eQTL 8.37e-03 -0.162 0.061 0.297 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000028839 TBPL1 348694 sc-eQTL 9.56e-01 0.0061 0.11 0.293 B_Activated L2
ENSG00000112339 HBS1L -802192 sc-eQTL 4.61e-02 0.227 0.113 0.293 B_Activated L2
ENSG00000118515 SGK1 -17248 sc-eQTL 1.16e-03 -0.307 0.093 0.293 B_Activated L2
ENSG00000028839 TBPL1 348694 sc-eQTL 8.60e-01 0.0177 0.0999 0.296 B_Intermediate L2
ENSG00000112339 HBS1L -802192 sc-eQTL 3.48e-01 0.0831 0.0882 0.296 B_Intermediate L2
ENSG00000118515 SGK1 -17248 sc-eQTL 5.71e-04 -0.311 0.089 0.296 B_Intermediate L2
ENSG00000028839 TBPL1 348694 sc-eQTL 5.89e-01 -0.0529 0.0978 0.295 B_Memory L2
ENSG00000112339 HBS1L -802192 sc-eQTL 5.94e-01 -0.047 0.088 0.295 B_Memory L2
ENSG00000118515 SGK1 -17248 sc-eQTL 4.41e-01 -0.063 0.0817 0.295 B_Memory L2
ENSG00000028839 TBPL1 348694 sc-eQTL 7.32e-01 -0.0313 0.0911 0.297 B_Naive1 L2
ENSG00000112339 HBS1L -802192 sc-eQTL 6.58e-02 0.145 0.0785 0.297 B_Naive1 L2
ENSG00000118515 SGK1 -17248 sc-eQTL 3.44e-02 -0.16 0.0749 0.297 B_Naive1 L2
ENSG00000028839 TBPL1 348694 sc-eQTL 9.26e-01 -0.00894 0.0959 0.296 B_Naive2 L2
ENSG00000112339 HBS1L -802192 sc-eQTL 8.35e-01 -0.0184 0.0884 0.296 B_Naive2 L2
ENSG00000118515 SGK1 -17248 sc-eQTL 1.49e-01 -0.126 0.0871 0.296 B_Naive2 L2
ENSG00000028839 TBPL1 348694 sc-eQTL 9.98e-01 0.000179 0.0945 0.305 CD4_CTL L2
ENSG00000112339 HBS1L -802192 sc-eQTL 7.26e-01 -0.034 0.097 0.305 CD4_CTL L2
ENSG00000118513 MYB -880444 sc-eQTL 3.80e-02 -0.135 0.0648 0.305 CD4_CTL L2
ENSG00000118515 SGK1 -17248 sc-eQTL 1.63e-02 -0.181 0.0748 0.305 CD4_CTL L2
ENSG00000028839 TBPL1 348694 sc-eQTL 1.55e-01 0.108 0.0754 0.297 CD4_Naive L2
ENSG00000112339 HBS1L -802192 sc-eQTL 6.25e-01 0.0259 0.0528 0.297 CD4_Naive L2
ENSG00000118513 MYB -880444 sc-eQTL 1.06e-01 -0.0898 0.0553 0.297 CD4_Naive L2
ENSG00000118515 SGK1 -17248 sc-eQTL 2.20e-02 -0.125 0.054 0.297 CD4_Naive L2
ENSG00000028839 TBPL1 348694 sc-eQTL 4.89e-01 0.0563 0.0812 0.297 CD4_TCM L2
ENSG00000112339 HBS1L -802192 sc-eQTL 3.97e-01 0.0557 0.0657 0.297 CD4_TCM L2
ENSG00000118513 MYB -880444 sc-eQTL 3.85e-01 -0.0557 0.0641 0.297 CD4_TCM L2
ENSG00000118515 SGK1 -17248 sc-eQTL 2.98e-06 -0.267 0.0555 0.297 CD4_TCM L2
ENSG00000028839 TBPL1 348694 sc-eQTL 4.76e-01 0.0668 0.0937 0.297 CD4_TEM L2
ENSG00000112339 HBS1L -802192 sc-eQTL 5.32e-01 0.0495 0.0792 0.297 CD4_TEM L2
ENSG00000118513 MYB -880444 sc-eQTL 6.97e-01 0.0271 0.0696 0.297 CD4_TEM L2
ENSG00000118515 SGK1 -17248 sc-eQTL 9.47e-06 -0.275 0.0606 0.297 CD4_TEM L2
ENSG00000028839 TBPL1 348694 sc-eQTL 6.32e-01 0.0402 0.0837 0.297 CD8_CTL L2
ENSG00000112339 HBS1L -802192 sc-eQTL 8.29e-01 0.017 0.0784 0.297 CD8_CTL L2
ENSG00000118513 MYB -880444 sc-eQTL 8.00e-01 -0.0175 0.0691 0.297 CD8_CTL L2
ENSG00000118515 SGK1 -17248 sc-eQTL 3.35e-02 -0.17 0.0795 0.297 CD8_CTL L2
ENSG00000028839 TBPL1 348694 sc-eQTL 6.36e-01 0.0424 0.0894 0.297 CD8_Naive L2
ENSG00000112339 HBS1L -802192 sc-eQTL 2.00e-01 -0.0909 0.0706 0.297 CD8_Naive L2
ENSG00000118513 MYB -880444 sc-eQTL 7.95e-01 0.0173 0.0665 0.297 CD8_Naive L2
ENSG00000118515 SGK1 -17248 sc-eQTL 1.07e-01 -0.095 0.0587 0.297 CD8_Naive L2
ENSG00000028839 TBPL1 348694 sc-eQTL 5.69e-01 0.0571 0.1 0.292 CD8_TCM L2
ENSG00000112339 HBS1L -802192 sc-eQTL 9.06e-01 -0.0101 0.0858 0.292 CD8_TCM L2
ENSG00000118513 MYB -880444 sc-eQTL 8.77e-01 -0.0125 0.0807 0.292 CD8_TCM L2
ENSG00000118515 SGK1 -17248 sc-eQTL 8.91e-03 -0.193 0.073 0.292 CD8_TCM L2
ENSG00000028839 TBPL1 348694 sc-eQTL 6.58e-01 0.0405 0.0912 0.297 CD8_TEM L2
ENSG00000112339 HBS1L -802192 sc-eQTL 8.97e-01 -0.0122 0.0939 0.297 CD8_TEM L2
ENSG00000118513 MYB -880444 sc-eQTL 2.02e-01 -0.0953 0.0744 0.297 CD8_TEM L2
ENSG00000118515 SGK1 -17248 sc-eQTL 1.91e-01 -0.114 0.0869 0.297 CD8_TEM L2
ENSG00000028839 TBPL1 348694 sc-eQTL 7.79e-01 0.0267 0.095 0.297 MAIT L2
ENSG00000112339 HBS1L -802192 sc-eQTL 6.71e-02 0.157 0.0854 0.297 MAIT L2
ENSG00000118515 SGK1 -17248 sc-eQTL 3.30e-02 -0.135 0.0629 0.297 MAIT L2
ENSG00000028839 TBPL1 348694 sc-eQTL 2.17e-01 0.125 0.101 0.307 NK_CD56bright L2
ENSG00000112339 HBS1L -802192 sc-eQTL 6.94e-01 -0.0349 0.0885 0.307 NK_CD56bright L2
ENSG00000118515 SGK1 -17248 sc-eQTL 1.68e-03 -0.247 0.0776 0.307 NK_CD56bright L2
ENSG00000028839 TBPL1 348694 sc-eQTL 5.71e-01 -0.0462 0.0814 0.3 NK_CD56dim L2
ENSG00000112339 HBS1L -802192 sc-eQTL 5.43e-01 0.0454 0.0746 0.3 NK_CD56dim L2
ENSG00000118515 SGK1 -17248 sc-eQTL 3.06e-01 -0.0839 0.0818 0.3 NK_CD56dim L2
ENSG00000028839 TBPL1 348694 sc-eQTL 6.48e-01 -0.0478 0.105 0.304 NK_HLA L2
ENSG00000112339 HBS1L -802192 sc-eQTL 1.89e-01 -0.126 0.0959 0.304 NK_HLA L2
ENSG00000118515 SGK1 -17248 sc-eQTL 9.27e-01 -0.00818 0.0887 0.304 NK_HLA L2
ENSG00000028839 TBPL1 348694 sc-eQTL 2.65e-01 0.0943 0.0843 0.3 NK_cytokine L2
ENSG00000112339 HBS1L -802192 sc-eQTL 9.31e-01 -0.00717 0.0822 0.3 NK_cytokine L2
ENSG00000118515 SGK1 -17248 sc-eQTL 2.92e-01 -0.0876 0.0829 0.3 NK_cytokine L2
ENSG00000028839 TBPL1 348694 sc-eQTL 4.50e-01 0.0911 0.12 0.296 PB L2
ENSG00000112339 HBS1L -802192 sc-eQTL 2.12e-01 0.119 0.0949 0.296 PB L2
ENSG00000118515 SGK1 -17248 sc-eQTL 2.69e-01 -0.106 0.0957 0.296 PB L2
ENSG00000028839 TBPL1 348694 sc-eQTL 7.62e-02 0.17 0.0952 0.298 Pro_T L2
ENSG00000112339 HBS1L -802192 sc-eQTL 1.04e-01 -0.123 0.0756 0.298 Pro_T L2
ENSG00000118515 SGK1 -17248 sc-eQTL 1.94e-01 -0.0904 0.0694 0.298 Pro_T L2
ENSG00000028839 TBPL1 348694 sc-eQTL 3.80e-01 0.0844 0.0961 0.297 Treg L2
ENSG00000112339 HBS1L -802192 sc-eQTL 8.72e-01 -0.0135 0.0832 0.297 Treg L2
ENSG00000118513 MYB -880444 sc-eQTL 8.36e-01 0.0149 0.072 0.297 Treg L2
ENSG00000118515 SGK1 -17248 sc-eQTL 1.40e-03 -0.225 0.0694 0.297 Treg L2
ENSG00000028839 TBPL1 348694 sc-eQTL 6.85e-01 -0.0415 0.102 0.295 cDC L2
ENSG00000112339 HBS1L -802192 sc-eQTL 2.08e-01 0.128 0.101 0.295 cDC L2
ENSG00000118513 MYB -880444 sc-eQTL 2.25e-01 -0.0888 0.0729 0.295 cDC L2
ENSG00000118515 SGK1 -17248 sc-eQTL 1.61e-04 -0.281 0.073 0.295 cDC L2
ENSG00000286887 AL355881.1 4563 sc-eQTL 1.32e-01 -0.132 0.0872 0.295 cDC L2
ENSG00000028839 TBPL1 348694 sc-eQTL 8.21e-01 0.0179 0.0793 0.297 cMono_IL1B L2
ENSG00000112339 HBS1L -802192 sc-eQTL 1.72e-02 0.184 0.0764 0.297 cMono_IL1B L2
ENSG00000118515 SGK1 -17248 sc-eQTL 4.72e-07 -0.278 0.0535 0.297 cMono_IL1B L2
ENSG00000286887 AL355881.1 4563 sc-eQTL 2.06e-05 -0.319 0.0733 0.297 cMono_IL1B L2
ENSG00000028839 TBPL1 348694 sc-eQTL 7.24e-01 -0.0319 0.09 0.297 cMono_S100A L2
ENSG00000112339 HBS1L -802192 sc-eQTL 8.55e-01 -0.0154 0.0845 0.297 cMono_S100A L2
ENSG00000118515 SGK1 -17248 sc-eQTL 3.58e-07 -0.235 0.0447 0.297 cMono_S100A L2
ENSG00000286887 AL355881.1 4563 sc-eQTL 3.61e-03 -0.217 0.0738 0.297 cMono_S100A L2
ENSG00000028839 TBPL1 348694 sc-eQTL 3.46e-01 0.117 0.124 0.303 gdT L2
ENSG00000112339 HBS1L -802192 sc-eQTL 7.23e-02 0.196 0.109 0.303 gdT L2
ENSG00000118515 SGK1 -17248 sc-eQTL 5.03e-01 -0.0571 0.085 0.303 gdT L2
ENSG00000028839 TBPL1 348694 sc-eQTL 9.82e-01 -0.00208 0.0924 0.296 intMono L2
ENSG00000112339 HBS1L -802192 sc-eQTL 6.93e-01 -0.0383 0.0969 0.296 intMono L2
ENSG00000118515 SGK1 -17248 sc-eQTL 1.19e-04 -0.247 0.063 0.296 intMono L2
ENSG00000286887 AL355881.1 4563 sc-eQTL 5.54e-01 -0.0537 0.0906 0.296 intMono L2
ENSG00000028839 TBPL1 348694 sc-eQTL 9.42e-01 -0.00702 0.0969 0.296 ncMono L2
ENSG00000112339 HBS1L -802192 sc-eQTL 2.41e-01 -0.104 0.0884 0.296 ncMono L2
ENSG00000118515 SGK1 -17248 sc-eQTL 2.16e-03 -0.19 0.0612 0.296 ncMono L2
ENSG00000286887 AL355881.1 4563 sc-eQTL 1.79e-03 -0.255 0.0807 0.296 ncMono L2
ENSG00000028839 TBPL1 348694 sc-eQTL 3.60e-01 -0.106 0.115 0.294 pDC L2
ENSG00000112339 HBS1L -802192 sc-eQTL 8.13e-01 -0.0224 0.0944 0.294 pDC L2
ENSG00000118513 MYB -880444 sc-eQTL 5.71e-01 -0.0462 0.0813 0.294 pDC L2
ENSG00000118515 SGK1 -17248 sc-eQTL 5.28e-02 -0.126 0.0648 0.294 pDC L2
ENSG00000286887 AL355881.1 4563 sc-eQTL 1.59e-01 -0.114 0.0806 0.294 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000028839 TBPL1 348694 sc-eQTL 8.54e-01 -0.0178 0.097 0.297 B_Memory LOneK1K
ENSG00000112339 HBS1L -802192 sc-eQTL 5.98e-01 0.0429 0.0811 0.297 B_Memory LOneK1K
ENSG00000118515 SGK1 -17248 sc-eQTL 5.48e-04 -0.257 0.0731 0.297 B_Memory LOneK1K
ENSG00000028839 TBPL1 348694 sc-eQTL 4.47e-01 -0.0694 0.091 0.297 B_Naive LOneK1K
ENSG00000112339 HBS1L -802192 sc-eQTL 3.07e-01 0.0765 0.0748 0.297 B_Naive LOneK1K
ENSG00000118515 SGK1 -17248 sc-eQTL 2.27e-02 -0.169 0.0737 0.297 B_Naive LOneK1K
ENSG00000028839 TBPL1 348694 sc-eQTL 6.52e-01 0.0324 0.0718 0.297 CD14_Mono LOneK1K
ENSG00000112339 HBS1L -802192 sc-eQTL 9.91e-02 0.115 0.0697 0.297 CD14_Mono LOneK1K
ENSG00000118515 SGK1 -17248 sc-eQTL 1.78e-07 -0.266 0.0492 0.297 CD14_Mono LOneK1K
ENSG00000286887 AL355881.1 4563 sc-eQTL 1.44e-06 -0.337 0.068 0.297 CD14_Mono LOneK1K
ENSG00000028839 TBPL1 348694 sc-eQTL 7.21e-01 0.0337 0.0943 0.297 CD16_Mono LOneK1K
ENSG00000112339 HBS1L -802192 sc-eQTL 9.94e-01 -0.000689 0.0856 0.297 CD16_Mono LOneK1K
ENSG00000118515 SGK1 -17248 sc-eQTL 1.12e-04 -0.209 0.053 0.297 CD16_Mono LOneK1K
ENSG00000286887 AL355881.1 4563 sc-eQTL 2.32e-02 -0.18 0.0787 0.297 CD16_Mono LOneK1K
ENSG00000028839 TBPL1 348694 sc-eQTL 8.00e-01 -0.019 0.0748 0.3 NK_CD56dim LOneK1K
ENSG00000112339 HBS1L -802192 sc-eQTL 8.83e-01 -0.00985 0.0669 0.3 NK_CD56dim LOneK1K
ENSG00000118515 SGK1 -17248 sc-eQTL 2.55e-01 -0.0854 0.0748 0.3 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000118515 SGK1 -17248 eQTL 0.00211 -0.076 0.0247 0.00428 0.00242 0.292
ENSG00000220378 KRT8P42 2169 eQTL 0.00666 -0.0894 0.0329 0.00292 0.0013 0.292

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000118515 SGK1 -17248 2.22e-05 2.67e-05 4.04e-06 1.3e-05 3.53e-06 1.09e-05 3.09e-05 3.5e-06 2.01e-05 1.04e-05 2.82e-05 1.08e-05 3.69e-05 1e-05 5.59e-06 1.2e-05 1.12e-05 1.75e-05 6.06e-06 4.89e-06 9.62e-06 2.19e-05 2.27e-05 6.42e-06 3.32e-05 5.73e-06 8.89e-06 8.93e-06 2.33e-05 1.95e-05 1.35e-05 1.42e-06 1.9e-06 5.65e-06 9.01e-06 4.57e-06 2.31e-06 2.76e-06 3.48e-06 2.54e-06 1.48e-06 2.73e-05 2.67e-06 2.62e-07 1.91e-06 2.87e-06 3.39e-06 1.38e-06 1.06e-06