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Genes within 1Mb (chr6:127381168:CT:C):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000093144 ECHDC1 37559 sc-eQTL 1.98e-01 0.0563 0.0436 0.53 B L1
ENSG00000118518 RNF146 114558 sc-eQTL 2.01e-01 -0.0889 0.0694 0.53 B L1
ENSG00000093144 ECHDC1 37559 sc-eQTL 5.84e-01 -0.0299 0.0545 0.53 CD4T L1
ENSG00000118518 RNF146 114558 sc-eQTL 4.05e-01 0.062 0.0744 0.53 CD4T L1
ENSG00000172673 THEMIS -537463 sc-eQTL 7.51e-01 -0.0181 0.0568 0.53 CD4T L1
ENSG00000214338 SOGA3 -138023 sc-eQTL 2.80e-01 -0.0522 0.0482 0.53 CD4T L1
ENSG00000093144 ECHDC1 37559 sc-eQTL 1.82e-01 0.0911 0.0681 0.53 CD8T L1
ENSG00000118518 RNF146 114558 sc-eQTL 2.54e-01 -0.1 0.0876 0.53 CD8T L1
ENSG00000172673 THEMIS -537463 sc-eQTL 3.50e-01 0.0638 0.0681 0.53 CD8T L1
ENSG00000227945 AL590006.1 -646718 sc-eQTL 2.00e-01 0.0875 0.068 0.53 CD8T L1
ENSG00000093144 ECHDC1 37559 sc-eQTL 5.81e-01 0.0413 0.0746 0.538 DC L1
ENSG00000118518 RNF146 114558 sc-eQTL 7.84e-02 -0.16 0.0905 0.538 DC L1
ENSG00000093144 ECHDC1 37559 sc-eQTL 9.20e-01 -0.00544 0.0543 0.53 Mono L1
ENSG00000118518 RNF146 114558 sc-eQTL 5.32e-01 0.0377 0.0602 0.53 Mono L1
ENSG00000093144 ECHDC1 37559 sc-eQTL 1.21e-01 0.103 0.0659 0.53 NK L1
ENSG00000118518 RNF146 114558 sc-eQTL 5.50e-01 -0.0458 0.0765 0.53 NK L1
ENSG00000172673 THEMIS -537463 sc-eQTL 9.49e-01 -0.00553 0.0867 0.53 NK L1
ENSG00000093144 ECHDC1 37559 sc-eQTL 9.10e-01 -0.00689 0.0609 0.53 Other_T L1
ENSG00000118518 RNF146 114558 sc-eQTL 4.76e-01 -0.0623 0.0874 0.53 Other_T L1
ENSG00000172673 THEMIS -537463 sc-eQTL 2.18e-02 0.145 0.0628 0.53 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000093144 ECHDC1 37559 sc-eQTL 1.14e-01 -0.165 0.104 0.528 B_Activated L2
ENSG00000118518 RNF146 114558 sc-eQTL 9.89e-01 -0.00148 0.106 0.528 B_Activated L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 6.70e-01 0.0304 0.0713 0.53 B_Intermediate L2
ENSG00000118518 RNF146 114558 sc-eQTL 2.40e-04 -0.332 0.0887 0.53 B_Intermediate L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 7.48e-01 0.0257 0.0799 0.534 B_Memory L2
ENSG00000118518 RNF146 114558 sc-eQTL 8.98e-01 -0.0119 0.093 0.534 B_Memory L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 4.26e-02 0.106 0.0522 0.53 B_Naive1 L2
ENSG00000118518 RNF146 114558 sc-eQTL 2.71e-01 -0.0913 0.0826 0.53 B_Naive1 L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 8.82e-01 -0.0102 0.0688 0.532 B_Naive2 L2
ENSG00000118518 RNF146 114558 sc-eQTL 3.97e-01 0.0809 0.0953 0.532 B_Naive2 L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 5.10e-01 -0.0636 0.0964 0.536 CD4_CTL L2
ENSG00000118518 RNF146 114558 sc-eQTL 2.45e-01 0.11 0.0942 0.536 CD4_CTL L2
ENSG00000172673 THEMIS -537463 sc-eQTL 5.90e-01 0.0344 0.0637 0.536 CD4_CTL L2
ENSG00000214338 SOGA3 -138023 sc-eQTL 9.58e-01 0.00448 0.0852 0.536 CD4_CTL L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 6.09e-02 -0.125 0.0664 0.53 CD4_Naive L2
ENSG00000118518 RNF146 114558 sc-eQTL 4.43e-01 0.0614 0.0799 0.53 CD4_Naive L2
ENSG00000172673 THEMIS -537463 sc-eQTL 7.46e-01 -0.0186 0.0574 0.53 CD4_Naive L2
ENSG00000214338 SOGA3 -138023 sc-eQTL 4.78e-02 -0.108 0.0542 0.53 CD4_Naive L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 7.55e-02 0.124 0.0693 0.53 CD4_TCM L2
ENSG00000118518 RNF146 114558 sc-eQTL 9.27e-01 0.00835 0.0904 0.53 CD4_TCM L2
ENSG00000172673 THEMIS -537463 sc-eQTL 9.20e-01 -0.00669 0.0667 0.53 CD4_TCM L2
ENSG00000214338 SOGA3 -138023 sc-eQTL 3.97e-01 -0.0582 0.0685 0.53 CD4_TCM L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 2.33e-01 -0.0985 0.0823 0.53 CD4_TEM L2
ENSG00000118518 RNF146 114558 sc-eQTL 1.06e-01 -0.151 0.0933 0.53 CD4_TEM L2
ENSG00000172673 THEMIS -537463 sc-eQTL 1.93e-01 0.0977 0.0748 0.53 CD4_TEM L2
ENSG00000214338 SOGA3 -138023 sc-eQTL 1.16e-01 0.122 0.0772 0.53 CD4_TEM L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 8.38e-01 -0.0171 0.0832 0.53 CD8_CTL L2
ENSG00000118518 RNF146 114558 sc-eQTL 3.79e-01 -0.0866 0.0983 0.53 CD8_CTL L2
ENSG00000172673 THEMIS -537463 sc-eQTL 1.79e-01 0.0954 0.0708 0.53 CD8_CTL L2
ENSG00000227945 AL590006.1 -646718 sc-eQTL 2.67e-01 0.0784 0.0704 0.53 CD8_CTL L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 4.48e-02 0.169 0.0838 0.53 CD8_Naive L2
ENSG00000118518 RNF146 114558 sc-eQTL 6.20e-01 -0.045 0.0906 0.53 CD8_Naive L2
ENSG00000172673 THEMIS -537463 sc-eQTL 7.71e-01 0.0164 0.0565 0.53 CD8_Naive L2
ENSG00000227945 AL590006.1 -646718 sc-eQTL 2.00e-01 0.11 0.0859 0.53 CD8_Naive L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 5.59e-01 -0.051 0.0873 0.528 CD8_TCM L2
ENSG00000118518 RNF146 114558 sc-eQTL 9.09e-01 0.0117 0.101 0.528 CD8_TCM L2
ENSG00000172673 THEMIS -537463 sc-eQTL 2.88e-01 0.094 0.0881 0.528 CD8_TCM L2
ENSG00000227945 AL590006.1 -646718 sc-eQTL 9.27e-01 0.00741 0.0811 0.528 CD8_TCM L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 8.35e-01 0.0188 0.0903 0.53 CD8_TEM L2
ENSG00000118518 RNF146 114558 sc-eQTL 1.92e-01 -0.12 0.0918 0.53 CD8_TEM L2
ENSG00000172673 THEMIS -537463 sc-eQTL 7.87e-01 0.0222 0.0818 0.53 CD8_TEM L2
ENSG00000227945 AL590006.1 -646718 sc-eQTL 1.28e-01 0.107 0.0698 0.53 CD8_TEM L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 6.65e-01 -0.0377 0.087 0.53 MAIT L2
ENSG00000118518 RNF146 114558 sc-eQTL 6.06e-01 -0.0477 0.0922 0.53 MAIT L2
ENSG00000172673 THEMIS -537463 sc-eQTL 7.33e-02 0.131 0.073 0.53 MAIT L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 9.74e-01 0.00296 0.0922 0.536 NK_CD56bright L2
ENSG00000118518 RNF146 114558 sc-eQTL 7.76e-01 0.0275 0.0964 0.536 NK_CD56bright L2
ENSG00000172673 THEMIS -537463 sc-eQTL 8.47e-01 0.0135 0.0701 0.536 NK_CD56bright L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 7.65e-01 0.0222 0.0741 0.53 NK_CD56dim L2
ENSG00000118518 RNF146 114558 sc-eQTL 3.92e-01 0.0727 0.0848 0.53 NK_CD56dim L2
ENSG00000172673 THEMIS -537463 sc-eQTL 3.67e-01 -0.076 0.084 0.53 NK_CD56dim L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 5.35e-01 0.0595 0.0958 0.534 NK_HLA L2
ENSG00000118518 RNF146 114558 sc-eQTL 1.13e-02 -0.249 0.0974 0.534 NK_HLA L2
ENSG00000172673 THEMIS -537463 sc-eQTL 7.24e-01 0.0273 0.0771 0.534 NK_HLA L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 5.03e-01 0.0552 0.0823 0.53 NK_cytokine L2
ENSG00000118518 RNF146 114558 sc-eQTL 1.79e-01 -0.114 0.0846 0.53 NK_cytokine L2
ENSG00000172673 THEMIS -537463 sc-eQTL 7.30e-01 0.0278 0.0804 0.53 NK_cytokine L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 9.04e-01 0.0116 0.0957 0.53 PB L2
ENSG00000118518 RNF146 114558 sc-eQTL 7.66e-02 0.226 0.126 0.53 PB L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 2.41e-01 0.085 0.0724 0.526 Pro_T L2
ENSG00000118518 RNF146 114558 sc-eQTL 8.44e-01 -0.0175 0.0888 0.526 Pro_T L2
ENSG00000172673 THEMIS -537463 sc-eQTL 8.10e-01 0.0149 0.0617 0.526 Pro_T L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 7.97e-01 0.0222 0.0861 0.53 Treg L2
ENSG00000118518 RNF146 114558 sc-eQTL 3.19e-01 0.0932 0.0933 0.53 Treg L2
ENSG00000172673 THEMIS -537463 sc-eQTL 9.86e-01 0.00157 0.0918 0.53 Treg L2
ENSG00000214338 SOGA3 -138023 sc-eQTL 7.95e-02 0.136 0.0773 0.53 Treg L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 7.72e-01 0.0254 0.0874 0.541 cDC L2
ENSG00000118518 RNF146 114558 sc-eQTL 6.97e-02 -0.175 0.0956 0.541 cDC L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 8.76e-01 -0.00954 0.0609 0.53 cMono_IL1B L2
ENSG00000118518 RNF146 114558 sc-eQTL 7.59e-01 -0.0221 0.072 0.53 cMono_IL1B L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 3.39e-01 -0.0681 0.071 0.53 cMono_S100A L2
ENSG00000118518 RNF146 114558 sc-eQTL 5.62e-01 -0.0448 0.0772 0.53 cMono_S100A L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 5.90e-01 -0.0572 0.106 0.545 gdT L2
ENSG00000118518 RNF146 114558 sc-eQTL 3.22e-02 -0.228 0.106 0.545 gdT L2
ENSG00000172673 THEMIS -537463 sc-eQTL 2.27e-01 0.122 0.101 0.545 gdT L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 3.27e-01 0.0789 0.0803 0.531 intMono L2
ENSG00000118518 RNF146 114558 sc-eQTL 9.12e-02 0.143 0.0843 0.531 intMono L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 9.92e-01 0.000844 0.0852 0.532 ncMono L2
ENSG00000118518 RNF146 114558 sc-eQTL 6.31e-01 0.0395 0.0821 0.532 ncMono L2
ENSG00000093144 ECHDC1 37559 sc-eQTL 2.09e-01 0.108 0.0855 0.571 pDC L2
ENSG00000118518 RNF146 114558 sc-eQTL 3.33e-01 -0.106 0.109 0.571 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000093144 ECHDC1 37559 sc-eQTL 7.43e-01 -0.0203 0.0618 0.53 B_Memory LOneK1K
ENSG00000118518 RNF146 114558 sc-eQTL 5.27e-02 -0.171 0.088 0.53 B_Memory LOneK1K
ENSG00000093144 ECHDC1 37559 sc-eQTL 3.23e-02 0.102 0.0474 0.53 B_Naive LOneK1K
ENSG00000118518 RNF146 114558 sc-eQTL 6.25e-01 -0.0402 0.0821 0.53 B_Naive LOneK1K
ENSG00000093144 ECHDC1 37559 sc-eQTL 5.09e-01 -0.0367 0.0556 0.53 CD14_Mono LOneK1K
ENSG00000118518 RNF146 114558 sc-eQTL 5.16e-01 -0.043 0.0662 0.53 CD14_Mono LOneK1K
ENSG00000093144 ECHDC1 37559 sc-eQTL 4.46e-01 0.0582 0.0762 0.532 CD16_Mono LOneK1K
ENSG00000118518 RNF146 114558 sc-eQTL 3.66e-02 0.148 0.0705 0.532 CD16_Mono LOneK1K
ENSG00000093144 ECHDC1 37559 sc-eQTL 1.13e-01 0.111 0.07 0.53 NK_CD56dim LOneK1K
ENSG00000118518 RNF146 114558 sc-eQTL 4.07e-01 -0.0664 0.0799 0.53 NK_CD56dim LOneK1K
ENSG00000172673 THEMIS -537463 sc-eQTL 7.73e-01 -0.0248 0.0861 0.53 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000093144 ECHDC1 37559 eQTL 4.8300000000000004e-36 -0.206 0.0157 0.0 0.0 0.425

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000093144 ECHDC1 37559 7.44e-05 3.82e-05 7.01e-06 9.98e-06 3.82e-06 1.52e-05 5.51e-05 2.14e-06 2.13e-05 6.68e-06 2.88e-05 9.35e-06 4.4e-05 7.53e-06 5.99e-06 1.43e-05 1.33e-05 2.26e-05 5.66e-06 4.19e-06 8.31e-06 3.64e-05 4.68e-05 5.67e-06 3.01e-05 5.29e-06 9.29e-06 6.17e-06 4.58e-05 1.81e-05 1.24e-05 1.03e-06 1.68e-06 3.7e-06 7.28e-06 3.35e-06 1.72e-06 2.15e-06 2.22e-06 3.2e-06 1.11e-06 7.99e-05 4.84e-06 2.27e-07 1.48e-06 2.71e-06 3.33e-06 7.48e-07 1.37e-06