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Genes within 1Mb (chr6:127175081:C:G):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000093144 ECHDC1 -168528 sc-eQTL 8.83e-01 0.00618 0.042 0.519 B L1
ENSG00000118518 RNF146 -91529 sc-eQTL 9.24e-01 0.00639 0.0669 0.519 B L1
ENSG00000203760 CENPW 834907 sc-eQTL 5.47e-01 -0.0399 0.066 0.519 B L1
ENSG00000093144 ECHDC1 -168528 sc-eQTL 7.86e-01 -0.0139 0.0513 0.519 CD4T L1
ENSG00000118518 RNF146 -91529 sc-eQTL 9.80e-01 -0.00179 0.0701 0.519 CD4T L1
ENSG00000172673 THEMIS -743550 sc-eQTL 1.14e-01 -0.0845 0.0532 0.519 CD4T L1
ENSG00000214338 SOGA3 -344110 sc-eQTL 7.90e-01 -0.0121 0.0455 0.519 CD4T L1
ENSG00000093144 ECHDC1 -168528 sc-eQTL 6.89e-01 -0.0251 0.0625 0.519 CD8T L1
ENSG00000118518 RNF146 -91529 sc-eQTL 4.44e-01 0.0615 0.0803 0.519 CD8T L1
ENSG00000172673 THEMIS -743550 sc-eQTL 1.98e-01 -0.0803 0.0622 0.519 CD8T L1
ENSG00000227945 AL590006.1 -852805 sc-eQTL 7.65e-02 0.11 0.062 0.519 CD8T L1
ENSG00000093144 ECHDC1 -168528 sc-eQTL 8.48e-01 0.0134 0.0697 0.518 DC L1
ENSG00000118518 RNF146 -91529 sc-eQTL 9.41e-01 -0.0063 0.0852 0.518 DC L1
ENSG00000203760 CENPW 834907 sc-eQTL 9.93e-01 -0.00072 0.0798 0.518 DC L1
ENSG00000093144 ECHDC1 -168528 sc-eQTL 6.21e-02 0.094 0.0501 0.519 Mono L1
ENSG00000118518 RNF146 -91529 sc-eQTL 1.80e-01 -0.0752 0.0559 0.519 Mono L1
ENSG00000203760 CENPW 834907 sc-eQTL 1.17e-01 0.107 0.0681 0.519 Mono L1
ENSG00000093144 ECHDC1 -168528 sc-eQTL 5.21e-01 -0.0397 0.0617 0.521 NK L1
ENSG00000118518 RNF146 -91529 sc-eQTL 1.85e-02 -0.167 0.0704 0.521 NK L1
ENSG00000172673 THEMIS -743550 sc-eQTL 5.96e-01 -0.0428 0.0807 0.521 NK L1
ENSG00000093144 ECHDC1 -168528 sc-eQTL 5.07e-02 0.111 0.0565 0.519 Other_T L1
ENSG00000118518 RNF146 -91529 sc-eQTL 6.67e-01 -0.0353 0.0819 0.519 Other_T L1
ENSG00000172673 THEMIS -743550 sc-eQTL 4.96e-01 0.0405 0.0595 0.519 Other_T L1
ENSG00000203760 CENPW 834907 sc-eQTL 3.31e-01 -0.0467 0.0479 0.519 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000093144 ECHDC1 -168528 sc-eQTL 1.51e-01 -0.14 0.0973 0.528 B_Activated L2
ENSG00000118518 RNF146 -91529 sc-eQTL 9.44e-03 0.256 0.0974 0.528 B_Activated L2
ENSG00000203760 CENPW 834907 sc-eQTL 4.19e-01 -0.0558 0.0689 0.528 B_Activated L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 7.74e-01 -0.0193 0.0672 0.521 B_Intermediate L2
ENSG00000118518 RNF146 -91529 sc-eQTL 5.74e-01 0.0485 0.0862 0.521 B_Intermediate L2
ENSG00000203760 CENPW 834907 sc-eQTL 5.86e-01 0.047 0.0861 0.521 B_Intermediate L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 8.73e-01 0.012 0.0749 0.517 B_Memory L2
ENSG00000118518 RNF146 -91529 sc-eQTL 1.74e-01 -0.118 0.0868 0.517 B_Memory L2
ENSG00000203760 CENPW 834907 sc-eQTL 1.95e-01 -0.106 0.0814 0.517 B_Memory L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 4.90e-01 -0.0348 0.0503 0.519 B_Naive1 L2
ENSG00000118518 RNF146 -91529 sc-eQTL 6.00e-01 -0.0415 0.0791 0.519 B_Naive1 L2
ENSG00000203760 CENPW 834907 sc-eQTL 9.78e-01 -0.00239 0.0852 0.519 B_Naive1 L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 7.09e-01 0.0242 0.065 0.517 B_Naive2 L2
ENSG00000118518 RNF146 -91529 sc-eQTL 4.48e-02 0.18 0.0893 0.517 B_Naive2 L2
ENSG00000203760 CENPW 834907 sc-eQTL 8.51e-01 -0.0146 0.078 0.517 B_Naive2 L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 1.08e-01 0.144 0.0888 0.518 CD4_CTL L2
ENSG00000118518 RNF146 -91529 sc-eQTL 3.97e-01 0.0741 0.0874 0.518 CD4_CTL L2
ENSG00000172673 THEMIS -743550 sc-eQTL 7.94e-01 0.0154 0.059 0.518 CD4_CTL L2
ENSG00000214338 SOGA3 -344110 sc-eQTL 1.88e-01 -0.104 0.0786 0.518 CD4_CTL L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 7.87e-01 -0.0169 0.0626 0.519 CD4_Naive L2
ENSG00000118518 RNF146 -91529 sc-eQTL 2.75e-01 -0.0817 0.0746 0.519 CD4_Naive L2
ENSG00000172673 THEMIS -743550 sc-eQTL 2.70e-01 -0.0593 0.0536 0.519 CD4_Naive L2
ENSG00000214338 SOGA3 -344110 sc-eQTL 9.86e-01 0.000894 0.0511 0.519 CD4_Naive L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 9.81e-01 -0.00155 0.0658 0.519 CD4_TCM L2
ENSG00000118518 RNF146 -91529 sc-eQTL 4.22e-01 0.0684 0.0852 0.519 CD4_TCM L2
ENSG00000172673 THEMIS -743550 sc-eQTL 2.05e-01 -0.0797 0.0626 0.519 CD4_TCM L2
ENSG00000214338 SOGA3 -344110 sc-eQTL 4.88e-01 0.0449 0.0646 0.519 CD4_TCM L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 7.86e-01 -0.0205 0.0755 0.519 CD4_TEM L2
ENSG00000118518 RNF146 -91529 sc-eQTL 7.78e-01 0.0243 0.0859 0.519 CD4_TEM L2
ENSG00000172673 THEMIS -743550 sc-eQTL 9.05e-01 -0.00819 0.0687 0.519 CD4_TEM L2
ENSG00000214338 SOGA3 -344110 sc-eQTL 2.50e-02 -0.159 0.0702 0.519 CD4_TEM L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 7.11e-02 0.138 0.0759 0.519 CD8_CTL L2
ENSG00000118518 RNF146 -91529 sc-eQTL 6.74e-02 0.165 0.0898 0.519 CD8_CTL L2
ENSG00000172673 THEMIS -743550 sc-eQTL 4.37e-01 -0.0509 0.0653 0.519 CD8_CTL L2
ENSG00000227945 AL590006.1 -852805 sc-eQTL 7.20e-01 -0.0233 0.0649 0.519 CD8_CTL L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 3.79e-01 -0.0683 0.0774 0.519 CD8_Naive L2
ENSG00000118518 RNF146 -91529 sc-eQTL 9.39e-01 0.00637 0.0831 0.519 CD8_Naive L2
ENSG00000172673 THEMIS -743550 sc-eQTL 8.13e-02 -0.09 0.0514 0.519 CD8_Naive L2
ENSG00000227945 AL590006.1 -852805 sc-eQTL 7.55e-02 0.14 0.0784 0.519 CD8_Naive L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 9.95e-01 -0.000481 0.0805 0.514 CD8_TCM L2
ENSG00000118518 RNF146 -91529 sc-eQTL 3.42e-01 0.0887 0.0932 0.514 CD8_TCM L2
ENSG00000172673 THEMIS -743550 sc-eQTL 8.17e-01 -0.0189 0.0814 0.514 CD8_TCM L2
ENSG00000227945 AL590006.1 -852805 sc-eQTL 7.52e-01 0.0236 0.0746 0.514 CD8_TCM L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 4.41e-01 0.0694 0.0899 0.514 CD8_TEM L2
ENSG00000118518 RNF146 -91529 sc-eQTL 2.98e-01 -0.0957 0.0916 0.514 CD8_TEM L2
ENSG00000172673 THEMIS -743550 sc-eQTL 1.83e-02 -0.191 0.0804 0.514 CD8_TEM L2
ENSG00000227945 AL590006.1 -852805 sc-eQTL 5.25e-01 -0.0445 0.0699 0.514 CD8_TEM L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 5.79e-01 0.0449 0.0809 0.522 MAIT L2
ENSG00000118518 RNF146 -91529 sc-eQTL 5.79e-01 -0.0476 0.0858 0.522 MAIT L2
ENSG00000172673 THEMIS -743550 sc-eQTL 8.80e-01 0.0103 0.0684 0.522 MAIT L2
ENSG00000203760 CENPW 834907 sc-eQTL 9.36e-02 -0.116 0.0687 0.522 MAIT L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 1.71e-01 -0.12 0.0874 0.524 NK_CD56bright L2
ENSG00000118518 RNF146 -91529 sc-eQTL 2.29e-01 -0.111 0.0916 0.524 NK_CD56bright L2
ENSG00000172673 THEMIS -743550 sc-eQTL 3.31e-02 -0.142 0.0661 0.524 NK_CD56bright L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 7.43e-01 -0.0228 0.0695 0.524 NK_CD56dim L2
ENSG00000118518 RNF146 -91529 sc-eQTL 1.26e-01 -0.122 0.0793 0.524 NK_CD56dim L2
ENSG00000172673 THEMIS -743550 sc-eQTL 3.03e-01 -0.0813 0.0788 0.524 NK_CD56dim L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 7.17e-01 -0.0329 0.0906 0.525 NK_HLA L2
ENSG00000118518 RNF146 -91529 sc-eQTL 4.60e-02 -0.186 0.0926 0.525 NK_HLA L2
ENSG00000172673 THEMIS -743550 sc-eQTL 6.32e-01 0.0349 0.0728 0.525 NK_HLA L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 6.03e-01 -0.0394 0.0756 0.524 NK_cytokine L2
ENSG00000118518 RNF146 -91529 sc-eQTL 6.25e-01 -0.0382 0.0781 0.524 NK_cytokine L2
ENSG00000172673 THEMIS -743550 sc-eQTL 8.99e-01 -0.00942 0.0739 0.524 NK_cytokine L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 3.13e-01 0.0934 0.0921 0.552 PB L2
ENSG00000118518 RNF146 -91529 sc-eQTL 4.28e-01 -0.0984 0.124 0.552 PB L2
ENSG00000203760 CENPW 834907 sc-eQTL 9.97e-01 -0.00035 0.083 0.552 PB L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 5.82e-01 0.0384 0.0697 0.522 Pro_T L2
ENSG00000118518 RNF146 -91529 sc-eQTL 4.14e-01 0.0697 0.0851 0.522 Pro_T L2
ENSG00000172673 THEMIS -743550 sc-eQTL 2.43e-01 0.0691 0.059 0.522 Pro_T L2
ENSG00000203760 CENPW 834907 sc-eQTL 4.63e-01 -0.0338 0.046 0.522 Pro_T L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 2.91e-01 0.0856 0.0808 0.519 Treg L2
ENSG00000118518 RNF146 -91529 sc-eQTL 6.59e-01 0.0388 0.0879 0.519 Treg L2
ENSG00000172673 THEMIS -743550 sc-eQTL 2.84e-03 -0.255 0.0845 0.519 Treg L2
ENSG00000214338 SOGA3 -344110 sc-eQTL 9.51e-01 -0.00454 0.0733 0.519 Treg L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 7.33e-01 -0.0283 0.0829 0.524 cDC L2
ENSG00000118518 RNF146 -91529 sc-eQTL 3.19e-01 -0.0914 0.0914 0.524 cDC L2
ENSG00000203760 CENPW 834907 sc-eQTL 9.38e-01 -0.00669 0.0866 0.524 cDC L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 5.67e-01 0.0323 0.0563 0.519 cMono_IL1B L2
ENSG00000118518 RNF146 -91529 sc-eQTL 6.60e-02 -0.122 0.0661 0.519 cMono_IL1B L2
ENSG00000203760 CENPW 834907 sc-eQTL 9.27e-01 -0.00674 0.0734 0.519 cMono_IL1B L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 7.68e-02 0.117 0.066 0.519 cMono_S100A L2
ENSG00000118518 RNF146 -91529 sc-eQTL 8.73e-01 -0.0115 0.0722 0.519 cMono_S100A L2
ENSG00000203760 CENPW 834907 sc-eQTL 1.09e-01 0.129 0.0802 0.519 cMono_S100A L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 9.30e-01 -0.00872 0.0992 0.5 gdT L2
ENSG00000118518 RNF146 -91529 sc-eQTL 3.74e-01 0.0891 0.1 0.5 gdT L2
ENSG00000172673 THEMIS -743550 sc-eQTL 7.16e-01 0.0345 0.0946 0.5 gdT L2
ENSG00000203760 CENPW 834907 sc-eQTL 1.12e-01 -0.149 0.0932 0.5 gdT L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 4.24e-01 0.0612 0.0763 0.524 intMono L2
ENSG00000118518 RNF146 -91529 sc-eQTL 7.41e-02 0.144 0.08 0.524 intMono L2
ENSG00000203760 CENPW 834907 sc-eQTL 2.14e-01 0.106 0.0854 0.524 intMono L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 2.83e-02 0.175 0.0791 0.518 ncMono L2
ENSG00000118518 RNF146 -91529 sc-eQTL 5.75e-01 -0.0433 0.0771 0.518 ncMono L2
ENSG00000203760 CENPW 834907 sc-eQTL 2.15e-01 -0.104 0.0834 0.518 ncMono L2
ENSG00000093144 ECHDC1 -168528 sc-eQTL 8.86e-01 -0.0113 0.0785 0.511 pDC L2
ENSG00000118518 RNF146 -91529 sc-eQTL 7.13e-01 0.0366 0.0995 0.511 pDC L2
ENSG00000203760 CENPW 834907 sc-eQTL 3.79e-01 -0.0854 0.0968 0.511 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000093144 ECHDC1 -168528 sc-eQTL 8.84e-01 0.00845 0.0577 0.519 B_Memory LOneK1K
ENSG00000118518 RNF146 -91529 sc-eQTL 9.38e-01 0.00641 0.0829 0.519 B_Memory LOneK1K
ENSG00000203760 CENPW 834907 sc-eQTL 2.94e-01 -0.0919 0.0874 0.519 B_Memory LOneK1K
ENSG00000093144 ECHDC1 -168528 sc-eQTL 9.15e-01 0.00487 0.0457 0.519 B_Naive LOneK1K
ENSG00000118518 RNF146 -91529 sc-eQTL 5.23e-01 0.0501 0.0783 0.519 B_Naive LOneK1K
ENSG00000203760 CENPW 834907 sc-eQTL 5.14e-01 0.0545 0.0834 0.519 B_Naive LOneK1K
ENSG00000093144 ECHDC1 -168528 sc-eQTL 1.30e-01 0.0784 0.0516 0.519 CD14_Mono LOneK1K
ENSG00000118518 RNF146 -91529 sc-eQTL 1.11e-01 -0.0983 0.0614 0.519 CD14_Mono LOneK1K
ENSG00000203760 CENPW 834907 sc-eQTL 4.03e-01 0.063 0.0752 0.519 CD14_Mono LOneK1K
ENSG00000093144 ECHDC1 -168528 sc-eQTL 1.51e-02 0.172 0.0704 0.519 CD16_Mono LOneK1K
ENSG00000118518 RNF146 -91529 sc-eQTL 7.07e-01 0.0251 0.0666 0.519 CD16_Mono LOneK1K
ENSG00000203760 CENPW 834907 sc-eQTL 5.49e-01 0.0457 0.0762 0.519 CD16_Mono LOneK1K
ENSG00000093144 ECHDC1 -168528 sc-eQTL 5.55e-01 -0.0385 0.0651 0.524 NK_CD56dim LOneK1K
ENSG00000118518 RNF146 -91529 sc-eQTL 7.36e-02 -0.132 0.0735 0.524 NK_CD56dim LOneK1K
ENSG00000172673 THEMIS -743550 sc-eQTL 5.36e-01 -0.0493 0.0796 0.524 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000093144 ECHDC1 -168528 eQTL 0.0189 -0.0391 0.0166 0.00267 0.0 0.488
ENSG00000118518 RNF146 -91529 eQTL 0.02 -0.0276 0.0118 0.0 0.0 0.488

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000118518 RNF146 -91529 6.66e-06 9.39e-06 6.33e-07 3.85e-06 1.66e-06 2.03e-06 8.84e-06 1.29e-06 5.48e-06 3.3e-06 8.89e-06 3.68e-06 1.06e-05 3.14e-06 9.41e-07 4.63e-06 3.67e-06 3.81e-06 1.65e-06 1.77e-06 2.66e-06 7.57e-06 5.44e-06 1.92e-06 1.02e-05 2.34e-06 3.25e-06 1.86e-06 6.12e-06 7.09e-06 3.57e-06 4.96e-07 7.21e-07 2.22e-06 2.59e-06 1.11e-06 1.09e-06 4.5e-07 1.05e-06 6.39e-07 6.7e-07 8.83e-06 8.3e-07 1.58e-07 7.57e-07 1.07e-06 1.13e-06 7.35e-07 4.54e-07