logo

Genes within 1Mb (chr6:127121947:T:C):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000093144 ECHDC1 -221662 sc-eQTL 6.55e-01 0.0191 0.0427 0.558 B L1
ENSG00000118518 RNF146 -144663 sc-eQTL 8.34e-01 -0.0142 0.0681 0.558 B L1
ENSG00000203760 CENPW 781773 sc-eQTL 3.93e-01 -0.0574 0.0671 0.558 B L1
ENSG00000093144 ECHDC1 -221662 sc-eQTL 4.30e-01 -0.0413 0.0522 0.558 CD4T L1
ENSG00000118518 RNF146 -144663 sc-eQTL 9.21e-01 -0.00707 0.0714 0.558 CD4T L1
ENSG00000172673 THEMIS -796684 sc-eQTL 1.77e-01 -0.0735 0.0543 0.558 CD4T L1
ENSG00000214338 SOGA3 -397244 sc-eQTL 2.86e-01 -0.0494 0.0462 0.558 CD4T L1
ENSG00000093144 ECHDC1 -221662 sc-eQTL 9.96e-01 0.0003 0.0632 0.558 CD8T L1
ENSG00000118518 RNF146 -144663 sc-eQTL 6.46e-01 0.0374 0.0812 0.558 CD8T L1
ENSG00000172673 THEMIS -796684 sc-eQTL 1.27e-01 -0.096 0.0627 0.558 CD8T L1
ENSG00000227945 AL590006.1 -905939 sc-eQTL 1.75e-01 0.0856 0.0628 0.558 CD8T L1
ENSG00000093144 ECHDC1 -221662 sc-eQTL 9.46e-01 0.00481 0.0706 0.556 DC L1
ENSG00000118518 RNF146 -144663 sc-eQTL 4.81e-01 -0.0608 0.0861 0.556 DC L1
ENSG00000203760 CENPW 781773 sc-eQTL 4.80e-01 0.0571 0.0806 0.556 DC L1
ENSG00000093144 ECHDC1 -221662 sc-eQTL 2.89e-01 0.0542 0.051 0.558 Mono L1
ENSG00000118518 RNF146 -144663 sc-eQTL 9.72e-01 -0.00202 0.0568 0.558 Mono L1
ENSG00000203760 CENPW 781773 sc-eQTL 5.43e-02 0.133 0.0687 0.558 Mono L1
ENSG00000093144 ECHDC1 -221662 sc-eQTL 7.13e-01 -0.0231 0.0626 0.56 NK L1
ENSG00000118518 RNF146 -144663 sc-eQTL 1.09e-01 -0.116 0.072 0.56 NK L1
ENSG00000172673 THEMIS -796684 sc-eQTL 7.88e-01 -0.0221 0.082 0.56 NK L1
ENSG00000093144 ECHDC1 -221662 sc-eQTL 4.94e-02 0.112 0.0565 0.558 Other_T L1
ENSG00000118518 RNF146 -144663 sc-eQTL 6.58e-01 -0.0364 0.0819 0.558 Other_T L1
ENSG00000172673 THEMIS -796684 sc-eQTL 4.65e-01 0.0435 0.0595 0.558 Other_T L1
ENSG00000203760 CENPW 781773 sc-eQTL 7.74e-01 -0.0138 0.048 0.558 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000093144 ECHDC1 -221662 sc-eQTL 2.65e-01 -0.111 0.0988 0.564 B_Activated L2
ENSG00000118518 RNF146 -144663 sc-eQTL 2.20e-02 0.229 0.0992 0.564 B_Activated L2
ENSG00000203760 CENPW 781773 sc-eQTL 8.97e-01 -0.00909 0.07 0.564 B_Activated L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 9.55e-01 -0.00385 0.0677 0.56 B_Intermediate L2
ENSG00000118518 RNF146 -144663 sc-eQTL 5.35e-01 0.054 0.0868 0.56 B_Intermediate L2
ENSG00000203760 CENPW 781773 sc-eQTL 7.24e-01 0.0307 0.0869 0.56 B_Intermediate L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 7.25e-01 -0.0266 0.0756 0.558 B_Memory L2
ENSG00000118518 RNF146 -144663 sc-eQTL 1.33e-01 -0.132 0.0875 0.558 B_Memory L2
ENSG00000203760 CENPW 781773 sc-eQTL 3.93e-01 -0.0705 0.0824 0.558 B_Memory L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 4.15e-01 -0.0417 0.051 0.558 B_Naive1 L2
ENSG00000118518 RNF146 -144663 sc-eQTL 5.30e-01 -0.0505 0.0802 0.558 B_Naive1 L2
ENSG00000203760 CENPW 781773 sc-eQTL 6.37e-01 -0.0409 0.0863 0.558 B_Naive1 L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 5.97e-01 0.0348 0.0657 0.558 B_Naive2 L2
ENSG00000118518 RNF146 -144663 sc-eQTL 1.17e-01 0.143 0.0906 0.558 B_Naive2 L2
ENSG00000203760 CENPW 781773 sc-eQTL 9.79e-01 -0.00205 0.0789 0.558 B_Naive2 L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 2.53e-01 0.104 0.0906 0.557 CD4_CTL L2
ENSG00000118518 RNF146 -144663 sc-eQTL 4.05e-01 0.0742 0.0889 0.557 CD4_CTL L2
ENSG00000172673 THEMIS -796684 sc-eQTL 2.07e-01 0.0758 0.0598 0.557 CD4_CTL L2
ENSG00000214338 SOGA3 -397244 sc-eQTL 8.67e-01 0.0134 0.0803 0.557 CD4_CTL L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 2.98e-01 -0.0663 0.0636 0.558 CD4_Naive L2
ENSG00000118518 RNF146 -144663 sc-eQTL 1.54e-01 -0.109 0.0758 0.558 CD4_Naive L2
ENSG00000172673 THEMIS -796684 sc-eQTL 4.59e-01 -0.0405 0.0547 0.558 CD4_Naive L2
ENSG00000214338 SOGA3 -397244 sc-eQTL 4.37e-01 -0.0405 0.052 0.558 CD4_Naive L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 9.54e-01 0.00381 0.0665 0.558 CD4_TCM L2
ENSG00000118518 RNF146 -144663 sc-eQTL 3.52e-01 0.0802 0.0859 0.558 CD4_TCM L2
ENSG00000172673 THEMIS -796684 sc-eQTL 1.05e-01 -0.103 0.0631 0.558 CD4_TCM L2
ENSG00000214338 SOGA3 -397244 sc-eQTL 9.65e-01 0.00285 0.0653 0.558 CD4_TCM L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 7.89e-01 0.0205 0.0768 0.558 CD4_TEM L2
ENSG00000118518 RNF146 -144663 sc-eQTL 6.11e-01 0.0444 0.0873 0.558 CD4_TEM L2
ENSG00000172673 THEMIS -796684 sc-eQTL 8.81e-01 0.0105 0.0699 0.558 CD4_TEM L2
ENSG00000214338 SOGA3 -397244 sc-eQTL 8.33e-03 -0.189 0.0711 0.558 CD4_TEM L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 4.36e-02 0.156 0.0767 0.558 CD8_CTL L2
ENSG00000118518 RNF146 -144663 sc-eQTL 8.25e-02 0.159 0.0911 0.558 CD8_CTL L2
ENSG00000172673 THEMIS -796684 sc-eQTL 3.48e-01 -0.0622 0.0661 0.558 CD8_CTL L2
ENSG00000227945 AL590006.1 -905939 sc-eQTL 8.32e-01 -0.014 0.0658 0.558 CD8_CTL L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 3.23e-01 -0.0781 0.0788 0.558 CD8_Naive L2
ENSG00000118518 RNF146 -144663 sc-eQTL 7.90e-01 0.0225 0.0846 0.558 CD8_Naive L2
ENSG00000172673 THEMIS -796684 sc-eQTL 2.66e-02 -0.116 0.0521 0.558 CD8_Naive L2
ENSG00000227945 AL590006.1 -905939 sc-eQTL 2.11e-01 0.101 0.0802 0.558 CD8_Naive L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 7.75e-01 0.0233 0.0816 0.556 CD8_TCM L2
ENSG00000118518 RNF146 -144663 sc-eQTL 9.84e-01 0.00194 0.0947 0.556 CD8_TCM L2
ENSG00000172673 THEMIS -796684 sc-eQTL 5.81e-01 -0.0456 0.0825 0.556 CD8_TCM L2
ENSG00000227945 AL590006.1 -905939 sc-eQTL 7.96e-01 0.0196 0.0757 0.556 CD8_TCM L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 5.57e-01 0.0521 0.0887 0.548 CD8_TEM L2
ENSG00000118518 RNF146 -144663 sc-eQTL 3.40e-01 -0.0864 0.0903 0.548 CD8_TEM L2
ENSG00000172673 THEMIS -796684 sc-eQTL 2.98e-02 -0.174 0.0794 0.548 CD8_TEM L2
ENSG00000227945 AL590006.1 -905939 sc-eQTL 6.22e-01 0.034 0.0689 0.548 CD8_TEM L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 4.85e-01 0.0567 0.0811 0.558 MAIT L2
ENSG00000118518 RNF146 -144663 sc-eQTL 6.01e-01 -0.045 0.086 0.558 MAIT L2
ENSG00000172673 THEMIS -796684 sc-eQTL 5.29e-01 0.0432 0.0685 0.558 MAIT L2
ENSG00000203760 CENPW 781773 sc-eQTL 3.68e-01 -0.0624 0.0692 0.558 MAIT L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 3.17e-01 -0.0882 0.088 0.56 NK_CD56bright L2
ENSG00000118518 RNF146 -144663 sc-eQTL 4.94e-01 -0.0632 0.0922 0.56 NK_CD56bright L2
ENSG00000172673 THEMIS -796684 sc-eQTL 5.63e-03 -0.184 0.0659 0.56 NK_CD56bright L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 6.20e-01 -0.035 0.0705 0.56 NK_CD56dim L2
ENSG00000118518 RNF146 -144663 sc-eQTL 2.34e-01 -0.0962 0.0806 0.56 NK_CD56dim L2
ENSG00000172673 THEMIS -796684 sc-eQTL 7.72e-01 -0.0233 0.0801 0.56 NK_CD56dim L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 4.34e-01 0.0713 0.0909 0.562 NK_HLA L2
ENSG00000118518 RNF146 -144663 sc-eQTL 3.64e-01 -0.0853 0.0937 0.562 NK_HLA L2
ENSG00000172673 THEMIS -796684 sc-eQTL 4.02e-01 0.0613 0.0731 0.562 NK_HLA L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 3.23e-01 -0.0762 0.077 0.56 NK_cytokine L2
ENSG00000118518 RNF146 -144663 sc-eQTL 8.31e-01 -0.017 0.0796 0.56 NK_cytokine L2
ENSG00000172673 THEMIS -796684 sc-eQTL 9.03e-01 0.00921 0.0753 0.56 NK_cytokine L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 5.94e-02 0.182 0.0955 0.589 PB L2
ENSG00000118518 RNF146 -144663 sc-eQTL 1.89e-01 -0.171 0.129 0.589 PB L2
ENSG00000203760 CENPW 781773 sc-eQTL 5.79e-01 -0.0484 0.0869 0.589 PB L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 2.93e-01 0.074 0.0702 0.559 Pro_T L2
ENSG00000118518 RNF146 -144663 sc-eQTL 4.74e-01 0.0617 0.0859 0.559 Pro_T L2
ENSG00000172673 THEMIS -796684 sc-eQTL 4.30e-01 0.0472 0.0597 0.559 Pro_T L2
ENSG00000203760 CENPW 781773 sc-eQTL 6.04e-01 -0.0241 0.0465 0.559 Pro_T L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 4.32e-01 0.0648 0.0823 0.558 Treg L2
ENSG00000118518 RNF146 -144663 sc-eQTL 5.01e-01 0.0603 0.0894 0.558 Treg L2
ENSG00000172673 THEMIS -796684 sc-eQTL 3.04e-03 -0.258 0.086 0.558 Treg L2
ENSG00000214338 SOGA3 -397244 sc-eQTL 3.43e-01 0.0708 0.0744 0.558 Treg L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 5.94e-01 -0.0452 0.0845 0.561 cDC L2
ENSG00000118518 RNF146 -144663 sc-eQTL 3.99e-01 -0.0788 0.0932 0.561 cDC L2
ENSG00000203760 CENPW 781773 sc-eQTL 5.35e-01 0.0548 0.0882 0.561 cDC L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 7.43e-01 0.0189 0.0575 0.558 cMono_IL1B L2
ENSG00000118518 RNF146 -144663 sc-eQTL 4.93e-01 -0.0466 0.0679 0.558 cMono_IL1B L2
ENSG00000203760 CENPW 781773 sc-eQTL 7.70e-01 0.022 0.0749 0.558 cMono_IL1B L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 3.25e-01 0.0668 0.0676 0.558 cMono_S100A L2
ENSG00000118518 RNF146 -144663 sc-eQTL 7.00e-01 0.0283 0.0735 0.558 cMono_S100A L2
ENSG00000203760 CENPW 781773 sc-eQTL 1.39e-01 0.121 0.0818 0.558 cMono_S100A L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 8.81e-01 -0.0149 0.0994 0.545 gdT L2
ENSG00000118518 RNF146 -144663 sc-eQTL 4.02e-01 0.0844 0.1 0.545 gdT L2
ENSG00000172673 THEMIS -796684 sc-eQTL 2.93e-01 0.0997 0.0945 0.545 gdT L2
ENSG00000203760 CENPW 781773 sc-eQTL 8.18e-02 -0.163 0.0932 0.545 gdT L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 2.94e-01 0.0828 0.0786 0.56 intMono L2
ENSG00000118518 RNF146 -144663 sc-eQTL 4.38e-02 0.167 0.0824 0.56 intMono L2
ENSG00000203760 CENPW 781773 sc-eQTL 1.22e-01 0.137 0.0879 0.56 intMono L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 1.61e-01 0.112 0.0794 0.554 ncMono L2
ENSG00000118518 RNF146 -144663 sc-eQTL 9.27e-01 0.00705 0.077 0.554 ncMono L2
ENSG00000203760 CENPW 781773 sc-eQTL 2.40e-01 -0.0981 0.0832 0.554 ncMono L2
ENSG00000093144 ECHDC1 -221662 sc-eQTL 7.48e-01 0.0255 0.0793 0.556 pDC L2
ENSG00000118518 RNF146 -144663 sc-eQTL 3.97e-01 -0.0853 0.1 0.556 pDC L2
ENSG00000203760 CENPW 781773 sc-eQTL 4.83e-01 -0.0689 0.098 0.556 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000093144 ECHDC1 -221662 sc-eQTL 9.69e-01 -0.00229 0.0585 0.558 B_Memory LOneK1K
ENSG00000118518 RNF146 -144663 sc-eQTL 9.92e-01 -0.000858 0.084 0.558 B_Memory LOneK1K
ENSG00000203760 CENPW 781773 sc-eQTL 7.53e-01 -0.0279 0.0888 0.558 B_Memory LOneK1K
ENSG00000093144 ECHDC1 -221662 sc-eQTL 9.50e-01 0.00292 0.0463 0.558 B_Naive LOneK1K
ENSG00000118518 RNF146 -144663 sc-eQTL 5.94e-01 0.0424 0.0793 0.558 B_Naive LOneK1K
ENSG00000203760 CENPW 781773 sc-eQTL 7.10e-01 0.0314 0.0845 0.558 B_Naive LOneK1K
ENSG00000093144 ECHDC1 -221662 sc-eQTL 4.59e-01 0.0391 0.0526 0.558 CD14_Mono LOneK1K
ENSG00000118518 RNF146 -144663 sc-eQTL 6.48e-01 -0.0287 0.0628 0.558 CD14_Mono LOneK1K
ENSG00000203760 CENPW 781773 sc-eQTL 2.06e-01 0.0968 0.0763 0.558 CD14_Mono LOneK1K
ENSG00000093144 ECHDC1 -221662 sc-eQTL 4.08e-02 0.147 0.0715 0.558 CD16_Mono LOneK1K
ENSG00000118518 RNF146 -144663 sc-eQTL 2.66e-01 0.0749 0.0673 0.558 CD16_Mono LOneK1K
ENSG00000203760 CENPW 781773 sc-eQTL 7.66e-01 0.023 0.0771 0.558 CD16_Mono LOneK1K
ENSG00000093144 ECHDC1 -221662 sc-eQTL 6.77e-01 -0.0276 0.0661 0.56 NK_CD56dim LOneK1K
ENSG00000118518 RNF146 -144663 sc-eQTL 2.62e-01 -0.0842 0.0749 0.56 NK_CD56dim LOneK1K
ENSG00000172673 THEMIS -796684 sc-eQTL 8.38e-01 -0.0165 0.0808 0.56 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000093144 ECHDC1 -221662 eQTL 0.00335 -0.0487 0.0166 0.00217 0.0 0.487
ENSG00000118518 RNF146 -144663 eQTL 0.00749 -0.0317 0.0118 0.0 0.0 0.487

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000118518 RNF146 -144663 1.09e-05 1.24e-05 2.64e-06 8.21e-06 2.58e-06 5.23e-06 1.22e-05 2.2e-06 1.27e-05 5.43e-06 1.44e-05 6.46e-06 2e-05 5.48e-06 4.27e-06 9.06e-06 6.4e-06 1.03e-05 3.58e-06 3.14e-06 6.52e-06 1.08e-05 1.1e-05 3.69e-06 2.29e-05 4.36e-06 7.48e-06 5.35e-06 1.29e-05 8.34e-06 7.63e-06 9.49e-07 1.25e-06 3.3e-06 6.48e-06 3.37e-06 1.83e-06 2e-06 2.05e-06 2.1e-06 9.87e-07 1.88e-05 2.68e-06 3.05e-07 9.39e-07 2.32e-06 1.75e-06 1.06e-06 6.19e-07