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Genes within 1Mb (chr12:101484339:A:G):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000017427 IGF1 -997405 sc-eQTL 6.63e-01 -0.0156 0.0356 0.44 B L1
ENSG00000075188 NUP37 -635781 sc-eQTL 8.10e-01 -0.0149 0.062 0.44 B L1
ENSG00000111666 CHPT1 -212608 sc-eQTL 7.42e-02 -0.0671 0.0374 0.44 B L1
ENSG00000111670 GNPTAB -346620 sc-eQTL 4.29e-01 0.0432 0.0544 0.44 B L1
ENSG00000120800 UTP20 204234 sc-eQTL 3.54e-01 -0.0575 0.0619 0.44 B L1
ENSG00000120805 ARL1 76567 sc-eQTL 1.79e-01 -0.0715 0.053 0.44 B L1
ENSG00000120860 WASHC3 -577810 sc-eQTL 4.31e-01 -0.0336 0.0426 0.44 B L1
ENSG00000136048 DRAM1 -393241 sc-eQTL 7.60e-02 0.0856 0.048 0.44 B L1
ENSG00000139351 SYCP3 -255133 sc-eQTL 5.73e-01 -0.0434 0.0768 0.44 B L1
ENSG00000185480 PARPBP -635846 sc-eQTL 4.14e-01 -0.0601 0.0735 0.44 B L1
ENSG00000281344 HELLPAR -713246 sc-eQTL 7.06e-01 0.026 0.0686 0.44 B L1
ENSG00000075188 NUP37 -635781 sc-eQTL 8.70e-01 -0.00913 0.0558 0.44 CD4T L1
ENSG00000111666 CHPT1 -212608 sc-eQTL 3.79e-04 -0.264 0.0731 0.44 CD4T L1
ENSG00000111670 GNPTAB -346620 sc-eQTL 7.39e-02 0.0931 0.0518 0.44 CD4T L1
ENSG00000120800 UTP20 204234 sc-eQTL 4.90e-01 -0.0399 0.0577 0.44 CD4T L1
ENSG00000120805 ARL1 76567 sc-eQTL 6.42e-01 0.0263 0.0564 0.44 CD4T L1
ENSG00000120860 WASHC3 -577810 sc-eQTL 3.65e-01 -0.0358 0.0395 0.44 CD4T L1
ENSG00000075188 NUP37 -635781 sc-eQTL 5.70e-01 -0.0401 0.0703 0.44 CD8T L1
ENSG00000111666 CHPT1 -212608 sc-eQTL 2.57e-03 -0.228 0.0747 0.44 CD8T L1
ENSG00000111670 GNPTAB -346620 sc-eQTL 4.69e-01 0.0362 0.05 0.44 CD8T L1
ENSG00000120800 UTP20 204234 sc-eQTL 7.70e-01 0.0185 0.0632 0.44 CD8T L1
ENSG00000120805 ARL1 76567 sc-eQTL 8.18e-01 0.0161 0.0697 0.44 CD8T L1
ENSG00000120860 WASHC3 -577810 sc-eQTL 1.94e-01 -0.0643 0.0493 0.44 CD8T L1
ENSG00000136048 DRAM1 -393241 sc-eQTL 7.03e-01 -0.027 0.071 0.44 CD8T L1
ENSG00000075188 NUP37 -635781 sc-eQTL 1.16e-01 0.125 0.0789 0.441 DC L1
ENSG00000111666 CHPT1 -212608 sc-eQTL 1.19e-02 -0.181 0.0714 0.441 DC L1
ENSG00000111670 GNPTAB -346620 sc-eQTL 8.56e-02 0.137 0.0792 0.441 DC L1
ENSG00000120800 UTP20 204234 sc-eQTL 8.62e-02 0.146 0.0849 0.441 DC L1
ENSG00000120805 ARL1 76567 sc-eQTL 8.96e-01 -0.0116 0.0885 0.441 DC L1
ENSG00000120860 WASHC3 -577810 sc-eQTL 2.17e-01 -0.094 0.0759 0.441 DC L1
ENSG00000136048 DRAM1 -393241 sc-eQTL 2.37e-01 -0.0743 0.0627 0.441 DC L1
ENSG00000139354 GAS2L3 910656 sc-eQTL 4.52e-01 0.0595 0.0789 0.441 DC L1
ENSG00000185480 PARPBP -635846 sc-eQTL 8.02e-01 0.0208 0.0829 0.441 DC L1
ENSG00000075188 NUP37 -635781 sc-eQTL 1.90e-01 0.0864 0.0658 0.44 Mono L1
ENSG00000111666 CHPT1 -212608 sc-eQTL 3.79e-01 -0.0492 0.0558 0.44 Mono L1
ENSG00000111670 GNPTAB -346620 sc-eQTL 9.64e-01 -0.00315 0.0701 0.44 Mono L1
ENSG00000120800 UTP20 204234 sc-eQTL 5.90e-02 0.147 0.0776 0.44 Mono L1
ENSG00000120805 ARL1 76567 sc-eQTL 1.04e-01 0.117 0.0715 0.44 Mono L1
ENSG00000120860 WASHC3 -577810 sc-eQTL 7.96e-01 -0.0164 0.0633 0.44 Mono L1
ENSG00000136048 DRAM1 -393241 sc-eQTL 5.15e-01 0.0336 0.0516 0.44 Mono L1
ENSG00000139354 GAS2L3 910656 sc-eQTL 4.92e-02 0.11 0.0557 0.44 Mono L1
ENSG00000075188 NUP37 -635781 sc-eQTL 8.83e-01 0.0105 0.0709 0.438 NK L1
ENSG00000111666 CHPT1 -212608 sc-eQTL 7.59e-03 -0.175 0.0647 0.438 NK L1
ENSG00000111670 GNPTAB -346620 sc-eQTL 7.45e-01 -0.0155 0.0477 0.438 NK L1
ENSG00000120800 UTP20 204234 sc-eQTL 8.06e-01 -0.0189 0.0768 0.438 NK L1
ENSG00000120805 ARL1 76567 sc-eQTL 6.92e-01 0.028 0.0706 0.438 NK L1
ENSG00000120860 WASHC3 -577810 sc-eQTL 5.01e-01 -0.0358 0.0532 0.438 NK L1
ENSG00000136048 DRAM1 -393241 sc-eQTL 3.47e-02 0.159 0.0749 0.438 NK L1
ENSG00000185480 PARPBP -635846 sc-eQTL 5.26e-01 0.0564 0.0888 0.438 NK L1
ENSG00000017427 IGF1 -997405 sc-eQTL 6.42e-01 -0.0126 0.027 0.44 Other_T L1
ENSG00000075188 NUP37 -635781 sc-eQTL 1.70e-01 0.0707 0.0513 0.44 Other_T L1
ENSG00000111666 CHPT1 -212608 sc-eQTL 1.10e-01 -0.12 0.0748 0.44 Other_T L1
ENSG00000111670 GNPTAB -346620 sc-eQTL 5.08e-02 0.106 0.0538 0.44 Other_T L1
ENSG00000120800 UTP20 204234 sc-eQTL 1.44e-01 -0.124 0.0844 0.44 Other_T L1
ENSG00000120805 ARL1 76567 sc-eQTL 2.82e-01 -0.0666 0.0617 0.44 Other_T L1
ENSG00000120860 WASHC3 -577810 sc-eQTL 2.68e-01 0.0609 0.0548 0.44 Other_T L1
ENSG00000136048 DRAM1 -393241 sc-eQTL 3.87e-01 -0.057 0.0658 0.44 Other_T L1
ENSG00000185480 PARPBP -635846 sc-eQTL 4.45e-01 0.042 0.0549 0.44 Other_T L1
ENSG00000281344 HELLPAR -713246 sc-eQTL 2.41e-01 -0.0749 0.0637 0.44 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000017427 IGF1 -997405 sc-eQTL 7.58e-01 0.00541 0.0175 0.457 B_Activated L2
ENSG00000075188 NUP37 -635781 sc-eQTL 7.24e-01 -0.0321 0.0908 0.457 B_Activated L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 6.87e-01 0.0271 0.0671 0.457 B_Activated L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 5.19e-01 -0.0615 0.0953 0.457 B_Activated L2
ENSG00000120800 UTP20 204234 sc-eQTL 8.18e-02 -0.16 0.0915 0.457 B_Activated L2
ENSG00000120805 ARL1 76567 sc-eQTL 9.42e-01 -0.00693 0.0953 0.457 B_Activated L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 7.88e-01 -0.0244 0.0908 0.457 B_Activated L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 1.06e-01 0.147 0.0905 0.457 B_Activated L2
ENSG00000139351 SYCP3 -255133 sc-eQTL 3.38e-01 -0.0718 0.0747 0.457 B_Activated L2
ENSG00000185480 PARPBP -635846 sc-eQTL 3.72e-01 -0.0673 0.0752 0.457 B_Activated L2
ENSG00000281344 HELLPAR -713246 sc-eQTL 3.54e-01 -0.0656 0.0707 0.457 B_Activated L2
ENSG00000017427 IGF1 -997405 sc-eQTL 5.30e-01 -0.0225 0.0358 0.438 B_Intermediate L2
ENSG00000075188 NUP37 -635781 sc-eQTL 4.63e-01 0.0656 0.0892 0.438 B_Intermediate L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 9.42e-01 -0.00348 0.0479 0.438 B_Intermediate L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 9.45e-01 0.00492 0.0708 0.438 B_Intermediate L2
ENSG00000120800 UTP20 204234 sc-eQTL 1.23e-01 -0.121 0.0783 0.438 B_Intermediate L2
ENSG00000120805 ARL1 76567 sc-eQTL 1.98e-01 0.114 0.0882 0.438 B_Intermediate L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 8.98e-01 0.00937 0.0732 0.438 B_Intermediate L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 2.30e-01 0.0941 0.0783 0.438 B_Intermediate L2
ENSG00000139351 SYCP3 -255133 sc-eQTL 4.73e-01 0.0593 0.0825 0.438 B_Intermediate L2
ENSG00000185480 PARPBP -635846 sc-eQTL 9.50e-01 0.00545 0.0867 0.438 B_Intermediate L2
ENSG00000281344 HELLPAR -713246 sc-eQTL 5.17e-01 0.0539 0.083 0.438 B_Intermediate L2
ENSG00000017427 IGF1 -997405 sc-eQTL 1.01e-01 -0.0534 0.0324 0.444 B_Memory L2
ENSG00000075188 NUP37 -635781 sc-eQTL 3.86e-01 0.0747 0.0861 0.444 B_Memory L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 8.94e-02 -0.0954 0.0559 0.444 B_Memory L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 9.72e-01 -0.00267 0.0771 0.444 B_Memory L2
ENSG00000120800 UTP20 204234 sc-eQTL 6.54e-01 -0.0379 0.0846 0.444 B_Memory L2
ENSG00000120805 ARL1 76567 sc-eQTL 6.81e-01 -0.0346 0.0841 0.444 B_Memory L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 7.31e-01 -0.0259 0.0752 0.444 B_Memory L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 7.29e-01 -0.0274 0.0789 0.444 B_Memory L2
ENSG00000139351 SYCP3 -255133 sc-eQTL 7.91e-01 -0.0215 0.0812 0.444 B_Memory L2
ENSG00000185480 PARPBP -635846 sc-eQTL 1.48e-01 -0.12 0.0827 0.444 B_Memory L2
ENSG00000281344 HELLPAR -713246 sc-eQTL 5.80e-01 0.0419 0.0756 0.444 B_Memory L2
ENSG00000017427 IGF1 -997405 sc-eQTL 9.63e-01 -0.00211 0.045 0.44 B_Naive1 L2
ENSG00000075188 NUP37 -635781 sc-eQTL 8.39e-01 0.0166 0.0815 0.44 B_Naive1 L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 8.76e-01 -0.00663 0.0424 0.44 B_Naive1 L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 6.31e-01 0.0288 0.0599 0.44 B_Naive1 L2
ENSG00000120800 UTP20 204234 sc-eQTL 2.46e-01 -0.0825 0.0709 0.44 B_Naive1 L2
ENSG00000120805 ARL1 76567 sc-eQTL 2.29e-01 -0.0955 0.0791 0.44 B_Naive1 L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 4.34e-01 -0.047 0.06 0.44 B_Naive1 L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 8.15e-01 0.0152 0.0651 0.44 B_Naive1 L2
ENSG00000139351 SYCP3 -255133 sc-eQTL 9.84e-01 -0.00181 0.0885 0.44 B_Naive1 L2
ENSG00000185480 PARPBP -635846 sc-eQTL 4.35e-01 -0.0672 0.086 0.44 B_Naive1 L2
ENSG00000281344 HELLPAR -713246 sc-eQTL 2.24e-02 -0.183 0.0797 0.44 B_Naive1 L2
ENSG00000017427 IGF1 -997405 sc-eQTL 8.59e-02 0.068 0.0394 0.442 B_Naive2 L2
ENSG00000075188 NUP37 -635781 sc-eQTL 6.35e-01 -0.0386 0.0813 0.442 B_Naive2 L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 4.64e-01 -0.0319 0.0435 0.442 B_Naive2 L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 9.65e-01 -0.00299 0.0675 0.442 B_Naive2 L2
ENSG00000120800 UTP20 204234 sc-eQTL 4.68e-01 -0.0567 0.0781 0.442 B_Naive2 L2
ENSG00000120805 ARL1 76567 sc-eQTL 2.13e-02 -0.197 0.0848 0.442 B_Naive2 L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 3.39e-01 -0.0715 0.0746 0.442 B_Naive2 L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 1.40e-01 0.109 0.0737 0.442 B_Naive2 L2
ENSG00000139351 SYCP3 -255133 sc-eQTL 5.53e-01 -0.0463 0.0779 0.442 B_Naive2 L2
ENSG00000185480 PARPBP -635846 sc-eQTL 4.47e-01 0.0684 0.0898 0.442 B_Naive2 L2
ENSG00000281344 HELLPAR -713246 sc-eQTL 4.85e-02 0.152 0.0768 0.442 B_Naive2 L2
ENSG00000075188 NUP37 -635781 sc-eQTL 2.28e-01 0.106 0.0876 0.448 CD4_CTL L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 1.20e-01 -0.137 0.0876 0.448 CD4_CTL L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 1.97e-01 0.0994 0.0767 0.448 CD4_CTL L2
ENSG00000120800 UTP20 204234 sc-eQTL 2.18e-01 -0.104 0.0844 0.448 CD4_CTL L2
ENSG00000120805 ARL1 76567 sc-eQTL 9.14e-01 -0.00966 0.0898 0.448 CD4_CTL L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 2.90e-01 0.0911 0.0859 0.448 CD4_CTL L2
ENSG00000075188 NUP37 -635781 sc-eQTL 2.32e-01 -0.0772 0.0644 0.44 CD4_Naive L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 1.05e-04 -0.284 0.0719 0.44 CD4_Naive L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 3.70e-02 0.119 0.0569 0.44 CD4_Naive L2
ENSG00000120800 UTP20 204234 sc-eQTL 1.62e-01 -0.0874 0.0623 0.44 CD4_Naive L2
ENSG00000120805 ARL1 76567 sc-eQTL 4.14e-01 0.0554 0.0677 0.44 CD4_Naive L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 7.59e-01 -0.0146 0.0474 0.44 CD4_Naive L2
ENSG00000075188 NUP37 -635781 sc-eQTL 9.40e-01 -0.0051 0.0679 0.44 CD4_TCM L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 4.06e-03 -0.223 0.0768 0.44 CD4_TCM L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 5.61e-01 0.0353 0.0606 0.44 CD4_TCM L2
ENSG00000120800 UTP20 204234 sc-eQTL 9.09e-01 -0.00865 0.0758 0.44 CD4_TCM L2
ENSG00000120805 ARL1 76567 sc-eQTL 3.42e-01 -0.0674 0.0708 0.44 CD4_TCM L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 7.90e-02 -0.0816 0.0462 0.44 CD4_TCM L2
ENSG00000075188 NUP37 -635781 sc-eQTL 8.51e-01 -0.0152 0.0811 0.44 CD4_TEM L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 2.82e-03 -0.231 0.0764 0.44 CD4_TEM L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 3.07e-01 0.0768 0.075 0.44 CD4_TEM L2
ENSG00000120800 UTP20 204234 sc-eQTL 5.70e-01 0.0463 0.0813 0.44 CD4_TEM L2
ENSG00000120805 ARL1 76567 sc-eQTL 7.18e-01 0.0278 0.0768 0.44 CD4_TEM L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 6.02e-01 -0.0359 0.0688 0.44 CD4_TEM L2
ENSG00000075188 NUP37 -635781 sc-eQTL 5.77e-01 -0.0422 0.0754 0.44 CD8_CTL L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 2.93e-03 -0.228 0.0758 0.44 CD8_CTL L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 9.83e-01 -0.00131 0.0619 0.44 CD8_CTL L2
ENSG00000120800 UTP20 204234 sc-eQTL 5.19e-01 0.054 0.0837 0.44 CD8_CTL L2
ENSG00000120805 ARL1 76567 sc-eQTL 1.88e-01 0.109 0.0825 0.44 CD8_CTL L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 3.52e-01 -0.0658 0.0705 0.44 CD8_CTL L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 1.86e-01 -0.116 0.0875 0.44 CD8_CTL L2
ENSG00000075188 NUP37 -635781 sc-eQTL 7.58e-01 -0.0245 0.0793 0.44 CD8_Naive L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 1.81e-02 -0.185 0.0778 0.44 CD8_Naive L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 9.18e-01 0.0073 0.0708 0.44 CD8_Naive L2
ENSG00000120800 UTP20 204234 sc-eQTL 5.13e-01 0.0493 0.0752 0.44 CD8_Naive L2
ENSG00000120805 ARL1 76567 sc-eQTL 5.69e-01 0.0466 0.0817 0.44 CD8_Naive L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 8.52e-01 -0.0101 0.0538 0.44 CD8_Naive L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 3.19e-01 0.0828 0.0829 0.44 CD8_Naive L2
ENSG00000075188 NUP37 -635781 sc-eQTL 8.06e-01 0.021 0.0853 0.451 CD8_TCM L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 7.40e-03 -0.203 0.0751 0.451 CD8_TCM L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 4.33e-02 0.159 0.0784 0.451 CD8_TCM L2
ENSG00000120800 UTP20 204234 sc-eQTL 4.12e-01 -0.0709 0.0862 0.451 CD8_TCM L2
ENSG00000120805 ARL1 76567 sc-eQTL 3.15e-01 0.0852 0.0846 0.451 CD8_TCM L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 4.22e-01 -0.0611 0.0758 0.451 CD8_TCM L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 6.52e-01 0.0374 0.0828 0.451 CD8_TCM L2
ENSG00000075188 NUP37 -635781 sc-eQTL 8.11e-01 0.0207 0.0865 0.434 CD8_TEM L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 2.42e-01 -0.0956 0.0815 0.434 CD8_TEM L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 8.38e-01 0.0179 0.0876 0.434 CD8_TEM L2
ENSG00000120800 UTP20 204234 sc-eQTL 9.30e-01 0.00827 0.094 0.434 CD8_TEM L2
ENSG00000120805 ARL1 76567 sc-eQTL 7.06e-01 -0.0339 0.0898 0.434 CD8_TEM L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 1.67e-01 -0.108 0.0782 0.434 CD8_TEM L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 6.34e-01 -0.0413 0.0866 0.434 CD8_TEM L2
ENSG00000017427 IGF1 -997405 sc-eQTL 5.47e-02 0.0565 0.0292 0.442 MAIT L2
ENSG00000075188 NUP37 -635781 sc-eQTL 4.05e-01 0.069 0.0826 0.442 MAIT L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 2.10e-01 -0.101 0.0803 0.442 MAIT L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 1.72e-01 0.0975 0.0712 0.442 MAIT L2
ENSG00000120800 UTP20 204234 sc-eQTL 7.29e-02 -0.153 0.085 0.442 MAIT L2
ENSG00000120805 ARL1 76567 sc-eQTL 2.09e-01 -0.11 0.0871 0.442 MAIT L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 9.21e-01 -0.00719 0.0727 0.442 MAIT L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 4.69e-01 0.0597 0.0823 0.442 MAIT L2
ENSG00000185480 PARPBP -635846 sc-eQTL 3.73e-01 0.0719 0.0806 0.442 MAIT L2
ENSG00000281344 HELLPAR -713246 sc-eQTL 7.37e-01 -0.024 0.0715 0.442 MAIT L2
ENSG00000075188 NUP37 -635781 sc-eQTL 6.89e-01 0.0366 0.0914 0.438 NK_CD56bright L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 6.23e-02 -0.123 0.0656 0.438 NK_CD56bright L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 6.41e-01 -0.0357 0.0764 0.438 NK_CD56bright L2
ENSG00000120800 UTP20 204234 sc-eQTL 9.58e-01 -0.00476 0.0892 0.438 NK_CD56bright L2
ENSG00000120805 ARL1 76567 sc-eQTL 7.17e-01 -0.0316 0.0872 0.438 NK_CD56bright L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 1.58e-01 0.111 0.0784 0.438 NK_CD56bright L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 3.40e-02 0.175 0.082 0.438 NK_CD56bright L2
ENSG00000185480 PARPBP -635846 sc-eQTL 7.96e-01 0.0227 0.0875 0.438 NK_CD56bright L2
ENSG00000075188 NUP37 -635781 sc-eQTL 8.82e-01 -0.0117 0.0782 0.435 NK_CD56dim L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 3.86e-03 -0.219 0.0749 0.435 NK_CD56dim L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 6.21e-01 -0.0286 0.0578 0.435 NK_CD56dim L2
ENSG00000120800 UTP20 204234 sc-eQTL 3.68e-01 -0.0723 0.0801 0.435 NK_CD56dim L2
ENSG00000120805 ARL1 76567 sc-eQTL 1.92e-01 -0.101 0.0773 0.435 NK_CD56dim L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 3.76e-01 -0.0589 0.0664 0.435 NK_CD56dim L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 9.98e-02 0.133 0.0802 0.435 NK_CD56dim L2
ENSG00000185480 PARPBP -635846 sc-eQTL 2.98e-01 0.0947 0.0907 0.435 NK_CD56dim L2
ENSG00000075188 NUP37 -635781 sc-eQTL 6.33e-01 0.0396 0.0828 0.438 NK_HLA L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 1.88e-01 -0.112 0.0847 0.438 NK_HLA L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 8.10e-01 -0.0164 0.0683 0.438 NK_HLA L2
ENSG00000120800 UTP20 204234 sc-eQTL 3.68e-01 -0.0805 0.0892 0.438 NK_HLA L2
ENSG00000120805 ARL1 76567 sc-eQTL 2.65e-02 0.201 0.0902 0.438 NK_HLA L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 7.53e-01 -0.0267 0.0848 0.438 NK_HLA L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 3.92e-01 0.0747 0.087 0.438 NK_HLA L2
ENSG00000185480 PARPBP -635846 sc-eQTL 6.82e-01 -0.0352 0.0857 0.438 NK_HLA L2
ENSG00000075188 NUP37 -635781 sc-eQTL 8.62e-01 -0.0138 0.0794 0.435 NK_cytokine L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 4.40e-02 -0.149 0.0736 0.435 NK_cytokine L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 5.80e-01 0.0313 0.0564 0.435 NK_cytokine L2
ENSG00000120800 UTP20 204234 sc-eQTL 8.12e-01 0.0188 0.0787 0.435 NK_cytokine L2
ENSG00000120805 ARL1 76567 sc-eQTL 1.00e-01 0.13 0.0787 0.435 NK_cytokine L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 8.19e-02 -0.108 0.0619 0.435 NK_cytokine L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 2.15e-01 0.101 0.0809 0.435 NK_cytokine L2
ENSG00000185480 PARPBP -635846 sc-eQTL 4.70e-01 -0.0635 0.0876 0.435 NK_cytokine L2
ENSG00000017427 IGF1 -997405 sc-eQTL 8.96e-01 0.00827 0.0631 0.433 PB L2
ENSG00000075188 NUP37 -635781 sc-eQTL 1.76e-01 -0.115 0.0843 0.433 PB L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 2.68e-01 0.0729 0.0656 0.433 PB L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 2.17e-01 0.117 0.0941 0.433 PB L2
ENSG00000120800 UTP20 204234 sc-eQTL 6.22e-01 -0.0538 0.109 0.433 PB L2
ENSG00000120805 ARL1 76567 sc-eQTL 5.68e-01 0.0383 0.0668 0.433 PB L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 2.20e-01 0.0946 0.0767 0.433 PB L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 1.05e-01 0.126 0.0774 0.433 PB L2
ENSG00000139351 SYCP3 -255133 sc-eQTL 1.04e-01 -0.147 0.0899 0.433 PB L2
ENSG00000185480 PARPBP -635846 sc-eQTL 2.76e-01 -0.0907 0.0829 0.433 PB L2
ENSG00000281344 HELLPAR -713246 sc-eQTL 3.87e-01 0.0667 0.0769 0.433 PB L2
ENSG00000017427 IGF1 -997405 sc-eQTL 5.78e-01 0.0162 0.0291 0.441 Pro_T L2
ENSG00000075188 NUP37 -635781 sc-eQTL 4.43e-01 -0.0451 0.0586 0.441 Pro_T L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 4.21e-01 -0.0626 0.0777 0.441 Pro_T L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 1.36e-01 0.0857 0.0573 0.441 Pro_T L2
ENSG00000120800 UTP20 204234 sc-eQTL 7.20e-01 -0.0295 0.0822 0.441 Pro_T L2
ENSG00000120805 ARL1 76567 sc-eQTL 4.97e-01 0.0422 0.0621 0.441 Pro_T L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 2.64e-01 0.0755 0.0674 0.441 Pro_T L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 1.55e-02 0.139 0.0571 0.441 Pro_T L2
ENSG00000185480 PARPBP -635846 sc-eQTL 5.87e-01 0.0292 0.0537 0.441 Pro_T L2
ENSG00000281344 HELLPAR -713246 sc-eQTL 3.13e-03 -0.172 0.0575 0.441 Pro_T L2
ENSG00000075188 NUP37 -635781 sc-eQTL 3.89e-01 0.0718 0.0832 0.44 Treg L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 2.41e-03 -0.261 0.0848 0.44 Treg L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 2.43e-01 -0.0885 0.0755 0.44 Treg L2
ENSG00000120800 UTP20 204234 sc-eQTL 7.58e-02 0.146 0.0819 0.44 Treg L2
ENSG00000120805 ARL1 76567 sc-eQTL 7.99e-01 -0.0218 0.0853 0.44 Treg L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 9.34e-01 0.00577 0.0693 0.44 Treg L2
ENSG00000075188 NUP37 -635781 sc-eQTL 3.72e-01 0.0691 0.0773 0.441 cDC L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 2.03e-02 -0.174 0.0745 0.441 cDC L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 2.35e-01 0.116 0.0971 0.441 cDC L2
ENSG00000120800 UTP20 204234 sc-eQTL 3.24e-01 0.0871 0.0881 0.441 cDC L2
ENSG00000120805 ARL1 76567 sc-eQTL 9.12e-01 0.0101 0.0916 0.441 cDC L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 4.89e-01 -0.0596 0.0859 0.441 cDC L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 6.05e-01 -0.0347 0.067 0.441 cDC L2
ENSG00000139354 GAS2L3 910656 sc-eQTL 1.94e-01 0.106 0.0816 0.441 cDC L2
ENSG00000185480 PARPBP -635846 sc-eQTL 6.38e-01 -0.036 0.0764 0.441 cDC L2
ENSG00000075188 NUP37 -635781 sc-eQTL 1.29e-01 0.113 0.0742 0.44 cMono_IL1B L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 2.66e-01 -0.0626 0.0561 0.44 cMono_IL1B L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 4.68e-01 -0.0542 0.0746 0.44 cMono_IL1B L2
ENSG00000120800 UTP20 204234 sc-eQTL 3.69e-01 0.0755 0.0838 0.44 cMono_IL1B L2
ENSG00000120805 ARL1 76567 sc-eQTL 1.24e-01 0.115 0.0748 0.44 cMono_IL1B L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 2.64e-01 -0.0725 0.0647 0.44 cMono_IL1B L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 4.54e-01 0.0415 0.0552 0.44 cMono_IL1B L2
ENSG00000139354 GAS2L3 910656 sc-eQTL 2.40e-01 0.0711 0.0603 0.44 cMono_IL1B L2
ENSG00000075188 NUP37 -635781 sc-eQTL 4.50e-01 0.0618 0.0817 0.44 cMono_S100A L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 5.30e-01 -0.0394 0.0626 0.44 cMono_S100A L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 1.42e-01 0.112 0.0759 0.44 cMono_S100A L2
ENSG00000120800 UTP20 204234 sc-eQTL 2.57e-01 0.101 0.0891 0.44 cMono_S100A L2
ENSG00000120805 ARL1 76567 sc-eQTL 4.87e-01 0.0584 0.0839 0.44 cMono_S100A L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 6.78e-01 0.0322 0.0776 0.44 cMono_S100A L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 8.30e-01 -0.013 0.0605 0.44 cMono_S100A L2
ENSG00000139354 GAS2L3 910656 sc-eQTL 6.83e-02 0.138 0.0752 0.44 cMono_S100A L2
ENSG00000075188 NUP37 -635781 sc-eQTL 6.72e-01 0.0457 0.108 0.433 gdT L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 3.46e-02 -0.212 0.0995 0.433 gdT L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 5.04e-01 0.0509 0.076 0.433 gdT L2
ENSG00000120800 UTP20 204234 sc-eQTL 3.32e-01 -0.0976 0.1 0.433 gdT L2
ENSG00000120805 ARL1 76567 sc-eQTL 6.31e-01 -0.0507 0.105 0.433 gdT L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 3.89e-01 -0.0847 0.0981 0.433 gdT L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 2.01e-02 -0.23 0.098 0.433 gdT L2
ENSG00000185480 PARPBP -635846 sc-eQTL 3.79e-03 0.28 0.0953 0.433 gdT L2
ENSG00000281344 HELLPAR -713246 sc-eQTL 2.23e-01 0.11 0.0894 0.433 gdT L2
ENSG00000075188 NUP37 -635781 sc-eQTL 5.34e-01 0.0504 0.0808 0.433 intMono L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 9.56e-01 0.00412 0.0739 0.433 intMono L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 4.65e-02 -0.172 0.086 0.433 intMono L2
ENSG00000120800 UTP20 204234 sc-eQTL 5.43e-01 0.0495 0.0812 0.433 intMono L2
ENSG00000120805 ARL1 76567 sc-eQTL 8.30e-01 0.0181 0.0841 0.433 intMono L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 9.14e-01 0.00876 0.0813 0.433 intMono L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 5.56e-01 -0.0418 0.071 0.433 intMono L2
ENSG00000139354 GAS2L3 910656 sc-eQTL 2.25e-01 0.0954 0.0784 0.433 intMono L2
ENSG00000075188 NUP37 -635781 sc-eQTL 8.57e-01 -0.0151 0.0839 0.43 ncMono L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 1.40e-01 -0.114 0.077 0.43 ncMono L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 6.35e-01 -0.0441 0.0927 0.43 ncMono L2
ENSG00000120800 UTP20 204234 sc-eQTL 6.74e-02 0.148 0.0804 0.43 ncMono L2
ENSG00000120805 ARL1 76567 sc-eQTL 8.93e-01 0.0105 0.078 0.43 ncMono L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 7.04e-01 -0.0285 0.0749 0.43 ncMono L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 1.54e-01 0.0993 0.0694 0.43 ncMono L2
ENSG00000139354 GAS2L3 910656 sc-eQTL 3.36e-01 0.0698 0.0724 0.43 ncMono L2
ENSG00000075188 NUP37 -635781 sc-eQTL 7.77e-01 0.0291 0.103 0.449 pDC L2
ENSG00000111666 CHPT1 -212608 sc-eQTL 2.68e-01 -0.0991 0.0891 0.449 pDC L2
ENSG00000111670 GNPTAB -346620 sc-eQTL 8.83e-01 -0.014 0.0947 0.449 pDC L2
ENSG00000120800 UTP20 204234 sc-eQTL 2.76e-01 0.103 0.094 0.449 pDC L2
ENSG00000120805 ARL1 76567 sc-eQTL 1.39e-01 -0.146 0.0985 0.449 pDC L2
ENSG00000120860 WASHC3 -577810 sc-eQTL 8.51e-01 -0.0162 0.0865 0.449 pDC L2
ENSG00000136048 DRAM1 -393241 sc-eQTL 7.72e-02 -0.118 0.0662 0.449 pDC L2
ENSG00000139354 GAS2L3 910656 sc-eQTL 7.75e-01 -0.0229 0.0799 0.449 pDC L2
ENSG00000185480 PARPBP -635846 sc-eQTL 8.23e-01 0.02 0.0888 0.449 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000017427 IGF1 -997405 sc-eQTL 5.15e-01 -0.0269 0.0413 0.44 B_Memory LOneK1K
ENSG00000075188 NUP37 -635781 sc-eQTL 4.55e-01 0.0621 0.0829 0.44 B_Memory LOneK1K
ENSG00000111666 CHPT1 -212608 sc-eQTL 8.01e-01 -0.011 0.0436 0.44 B_Memory LOneK1K
ENSG00000111670 GNPTAB -346620 sc-eQTL 8.64e-01 -0.0117 0.0686 0.44 B_Memory LOneK1K
ENSG00000120800 UTP20 204234 sc-eQTL 1.87e-01 -0.0931 0.0704 0.44 B_Memory LOneK1K
ENSG00000120805 ARL1 76567 sc-eQTL 3.45e-01 0.0754 0.0797 0.44 B_Memory LOneK1K
ENSG00000120860 WASHC3 -577810 sc-eQTL 8.16e-01 0.0139 0.0597 0.44 B_Memory LOneK1K
ENSG00000136048 DRAM1 -393241 sc-eQTL 1.64e-01 0.0993 0.0711 0.44 B_Memory LOneK1K
ENSG00000139351 SYCP3 -255133 sc-eQTL 5.73e-01 0.0464 0.0823 0.44 B_Memory LOneK1K
ENSG00000185480 PARPBP -635846 sc-eQTL 7.51e-01 -0.0274 0.0862 0.44 B_Memory LOneK1K
ENSG00000281344 HELLPAR -713246 sc-eQTL 3.45e-01 0.0806 0.0853 0.44 B_Memory LOneK1K
ENSG00000017427 IGF1 -997405 sc-eQTL 8.43e-01 0.00946 0.0477 0.44 B_Naive LOneK1K
ENSG00000075188 NUP37 -635781 sc-eQTL 9.92e-01 -0.000751 0.078 0.44 B_Naive LOneK1K
ENSG00000111666 CHPT1 -212608 sc-eQTL 7.50e-01 -0.0123 0.0385 0.44 B_Naive LOneK1K
ENSG00000111670 GNPTAB -346620 sc-eQTL 7.82e-01 0.0153 0.0552 0.44 B_Naive LOneK1K
ENSG00000120800 UTP20 204234 sc-eQTL 3.00e-01 -0.07 0.0674 0.44 B_Naive LOneK1K
ENSG00000120805 ARL1 76567 sc-eQTL 4.40e-02 -0.155 0.0763 0.44 B_Naive LOneK1K
ENSG00000120860 WASHC3 -577810 sc-eQTL 2.11e-01 -0.0722 0.0575 0.44 B_Naive LOneK1K
ENSG00000136048 DRAM1 -393241 sc-eQTL 3.85e-01 0.0526 0.0604 0.44 B_Naive LOneK1K
ENSG00000139351 SYCP3 -255133 sc-eQTL 7.73e-01 -0.0252 0.0873 0.44 B_Naive LOneK1K
ENSG00000185480 PARPBP -635846 sc-eQTL 5.09e-01 -0.0588 0.0888 0.44 B_Naive LOneK1K
ENSG00000281344 HELLPAR -713246 sc-eQTL 6.51e-01 -0.0367 0.0809 0.44 B_Naive LOneK1K
ENSG00000075188 NUP37 -635781 sc-eQTL 1.39e-01 0.102 0.0689 0.44 CD14_Mono LOneK1K
ENSG00000111666 CHPT1 -212608 sc-eQTL 3.17e-01 -0.056 0.0559 0.44 CD14_Mono LOneK1K
ENSG00000111670 GNPTAB -346620 sc-eQTL 6.95e-01 0.0283 0.072 0.44 CD14_Mono LOneK1K
ENSG00000120800 UTP20 204234 sc-eQTL 1.61e-01 0.119 0.0848 0.44 CD14_Mono LOneK1K
ENSG00000120805 ARL1 76567 sc-eQTL 8.63e-02 0.125 0.0724 0.44 CD14_Mono LOneK1K
ENSG00000120860 WASHC3 -577810 sc-eQTL 6.46e-01 -0.0292 0.0634 0.44 CD14_Mono LOneK1K
ENSG00000136048 DRAM1 -393241 sc-eQTL 4.30e-01 0.041 0.0519 0.44 CD14_Mono LOneK1K
ENSG00000139354 GAS2L3 910656 sc-eQTL 1.08e-01 0.0959 0.0594 0.44 CD14_Mono LOneK1K
ENSG00000075188 NUP37 -635781 sc-eQTL 9.18e-01 0.00819 0.0795 0.435 CD16_Mono LOneK1K
ENSG00000111666 CHPT1 -212608 sc-eQTL 6.36e-01 -0.0328 0.0694 0.435 CD16_Mono LOneK1K
ENSG00000111670 GNPTAB -346620 sc-eQTL 2.33e-01 -0.1 0.0837 0.435 CD16_Mono LOneK1K
ENSG00000120800 UTP20 204234 sc-eQTL 1.70e-01 0.111 0.0805 0.435 CD16_Mono LOneK1K
ENSG00000120805 ARL1 76567 sc-eQTL 7.14e-01 0.0294 0.0803 0.435 CD16_Mono LOneK1K
ENSG00000120860 WASHC3 -577810 sc-eQTL 3.48e-01 -0.0654 0.0695 0.435 CD16_Mono LOneK1K
ENSG00000136048 DRAM1 -393241 sc-eQTL 6.81e-01 0.0247 0.0601 0.435 CD16_Mono LOneK1K
ENSG00000139354 GAS2L3 910656 sc-eQTL 1.74e-01 0.0995 0.073 0.435 CD16_Mono LOneK1K
ENSG00000075188 NUP37 -635781 sc-eQTL 7.81e-01 0.0208 0.0749 0.435 NK_CD56dim LOneK1K
ENSG00000111666 CHPT1 -212608 sc-eQTL 5.34e-03 -0.202 0.0717 0.435 NK_CD56dim LOneK1K
ENSG00000111670 GNPTAB -346620 sc-eQTL 7.21e-01 -0.0179 0.05 0.435 NK_CD56dim LOneK1K
ENSG00000120800 UTP20 204234 sc-eQTL 6.44e-01 -0.0355 0.0767 0.435 NK_CD56dim LOneK1K
ENSG00000120805 ARL1 76567 sc-eQTL 5.89e-01 0.0385 0.0712 0.435 NK_CD56dim LOneK1K
ENSG00000120860 WASHC3 -577810 sc-eQTL 1.08e-01 -0.0925 0.0573 0.435 NK_CD56dim LOneK1K
ENSG00000136048 DRAM1 -393241 sc-eQTL 7.11e-02 0.139 0.0769 0.435 NK_CD56dim LOneK1K
ENSG00000185480 PARPBP -635846 sc-eQTL 6.26e-01 0.0444 0.0911 0.435 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000111666 CHPT1 -212608 eQTL 5.60e-04 -0.087 0.0251 0.0 0.0 0.429
ENSG00000120860 WASHC3 -577810 pQTL 0.00145 -0.0295 0.00924 0.0 0.00125 0.444

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000111666 CHPT1 -212608 1.59e-06 1.57e-06 2.9e-07 1.25e-06 4.2e-07 6.68e-07 1.25e-06 3.77e-07 1.7e-06 7.14e-07 1.97e-06 1.14e-06 2.69e-06 3.58e-07 3.95e-07 1.03e-06 1.16e-06 1.16e-06 5.99e-07 4.81e-07 7.33e-07 1.93e-06 1.46e-06 6.61e-07 2.41e-06 8.9e-07 1.02e-06 8.36e-07 1.65e-06 1.36e-06 7.63e-07 2.8e-07 3.32e-07 5.79e-07 6.86e-07 5.24e-07 7.24e-07 3.6e-07 5.18e-07 2.42e-07 3.68e-07 2.13e-06 3.01e-07 1.66e-07 3.14e-07 2.14e-07 3.02e-07 1.49e-07 2.57e-07