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Genes within 1Mb (chr12:101483568:C:T):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000017427 IGF1 -998176 sc-eQTL 6.63e-01 -0.0156 0.0356 0.44 B L1
ENSG00000075188 NUP37 -636552 sc-eQTL 8.10e-01 -0.0149 0.062 0.44 B L1
ENSG00000111666 CHPT1 -213379 sc-eQTL 7.42e-02 -0.0671 0.0374 0.44 B L1
ENSG00000111670 GNPTAB -347391 sc-eQTL 4.29e-01 0.0432 0.0544 0.44 B L1
ENSG00000120800 UTP20 203463 sc-eQTL 3.54e-01 -0.0575 0.0619 0.44 B L1
ENSG00000120805 ARL1 75796 sc-eQTL 1.79e-01 -0.0715 0.053 0.44 B L1
ENSG00000120860 WASHC3 -578581 sc-eQTL 4.31e-01 -0.0336 0.0426 0.44 B L1
ENSG00000136048 DRAM1 -394012 sc-eQTL 7.60e-02 0.0856 0.048 0.44 B L1
ENSG00000139351 SYCP3 -255904 sc-eQTL 5.73e-01 -0.0434 0.0768 0.44 B L1
ENSG00000185480 PARPBP -636617 sc-eQTL 4.14e-01 -0.0601 0.0735 0.44 B L1
ENSG00000281344 HELLPAR -714017 sc-eQTL 7.06e-01 0.026 0.0686 0.44 B L1
ENSG00000075188 NUP37 -636552 sc-eQTL 8.70e-01 -0.00913 0.0558 0.44 CD4T L1
ENSG00000111666 CHPT1 -213379 sc-eQTL 3.79e-04 -0.264 0.0731 0.44 CD4T L1
ENSG00000111670 GNPTAB -347391 sc-eQTL 7.39e-02 0.0931 0.0518 0.44 CD4T L1
ENSG00000120800 UTP20 203463 sc-eQTL 4.90e-01 -0.0399 0.0577 0.44 CD4T L1
ENSG00000120805 ARL1 75796 sc-eQTL 6.42e-01 0.0263 0.0564 0.44 CD4T L1
ENSG00000120860 WASHC3 -578581 sc-eQTL 3.65e-01 -0.0358 0.0395 0.44 CD4T L1
ENSG00000075188 NUP37 -636552 sc-eQTL 5.70e-01 -0.0401 0.0703 0.44 CD8T L1
ENSG00000111666 CHPT1 -213379 sc-eQTL 2.57e-03 -0.228 0.0747 0.44 CD8T L1
ENSG00000111670 GNPTAB -347391 sc-eQTL 4.69e-01 0.0362 0.05 0.44 CD8T L1
ENSG00000120800 UTP20 203463 sc-eQTL 7.70e-01 0.0185 0.0632 0.44 CD8T L1
ENSG00000120805 ARL1 75796 sc-eQTL 8.18e-01 0.0161 0.0697 0.44 CD8T L1
ENSG00000120860 WASHC3 -578581 sc-eQTL 1.94e-01 -0.0643 0.0493 0.44 CD8T L1
ENSG00000136048 DRAM1 -394012 sc-eQTL 7.03e-01 -0.027 0.071 0.44 CD8T L1
ENSG00000075188 NUP37 -636552 sc-eQTL 1.16e-01 0.125 0.0789 0.441 DC L1
ENSG00000111666 CHPT1 -213379 sc-eQTL 1.19e-02 -0.181 0.0714 0.441 DC L1
ENSG00000111670 GNPTAB -347391 sc-eQTL 8.56e-02 0.137 0.0792 0.441 DC L1
ENSG00000120800 UTP20 203463 sc-eQTL 8.62e-02 0.146 0.0849 0.441 DC L1
ENSG00000120805 ARL1 75796 sc-eQTL 8.96e-01 -0.0116 0.0885 0.441 DC L1
ENSG00000120860 WASHC3 -578581 sc-eQTL 2.17e-01 -0.094 0.0759 0.441 DC L1
ENSG00000136048 DRAM1 -394012 sc-eQTL 2.37e-01 -0.0743 0.0627 0.441 DC L1
ENSG00000139354 GAS2L3 909885 sc-eQTL 4.52e-01 0.0595 0.0789 0.441 DC L1
ENSG00000185480 PARPBP -636617 sc-eQTL 8.02e-01 0.0208 0.0829 0.441 DC L1
ENSG00000075188 NUP37 -636552 sc-eQTL 1.90e-01 0.0864 0.0658 0.44 Mono L1
ENSG00000111666 CHPT1 -213379 sc-eQTL 3.79e-01 -0.0492 0.0558 0.44 Mono L1
ENSG00000111670 GNPTAB -347391 sc-eQTL 9.64e-01 -0.00315 0.0701 0.44 Mono L1
ENSG00000120800 UTP20 203463 sc-eQTL 5.90e-02 0.147 0.0776 0.44 Mono L1
ENSG00000120805 ARL1 75796 sc-eQTL 1.04e-01 0.117 0.0715 0.44 Mono L1
ENSG00000120860 WASHC3 -578581 sc-eQTL 7.96e-01 -0.0164 0.0633 0.44 Mono L1
ENSG00000136048 DRAM1 -394012 sc-eQTL 5.15e-01 0.0336 0.0516 0.44 Mono L1
ENSG00000139354 GAS2L3 909885 sc-eQTL 4.92e-02 0.11 0.0557 0.44 Mono L1
ENSG00000075188 NUP37 -636552 sc-eQTL 8.83e-01 0.0105 0.0709 0.438 NK L1
ENSG00000111666 CHPT1 -213379 sc-eQTL 7.59e-03 -0.175 0.0647 0.438 NK L1
ENSG00000111670 GNPTAB -347391 sc-eQTL 7.45e-01 -0.0155 0.0477 0.438 NK L1
ENSG00000120800 UTP20 203463 sc-eQTL 8.06e-01 -0.0189 0.0768 0.438 NK L1
ENSG00000120805 ARL1 75796 sc-eQTL 6.92e-01 0.028 0.0706 0.438 NK L1
ENSG00000120860 WASHC3 -578581 sc-eQTL 5.01e-01 -0.0358 0.0532 0.438 NK L1
ENSG00000136048 DRAM1 -394012 sc-eQTL 3.47e-02 0.159 0.0749 0.438 NK L1
ENSG00000185480 PARPBP -636617 sc-eQTL 5.26e-01 0.0564 0.0888 0.438 NK L1
ENSG00000017427 IGF1 -998176 sc-eQTL 6.42e-01 -0.0126 0.027 0.44 Other_T L1
ENSG00000075188 NUP37 -636552 sc-eQTL 1.70e-01 0.0707 0.0513 0.44 Other_T L1
ENSG00000111666 CHPT1 -213379 sc-eQTL 1.10e-01 -0.12 0.0748 0.44 Other_T L1
ENSG00000111670 GNPTAB -347391 sc-eQTL 5.08e-02 0.106 0.0538 0.44 Other_T L1
ENSG00000120800 UTP20 203463 sc-eQTL 1.44e-01 -0.124 0.0844 0.44 Other_T L1
ENSG00000120805 ARL1 75796 sc-eQTL 2.82e-01 -0.0666 0.0617 0.44 Other_T L1
ENSG00000120860 WASHC3 -578581 sc-eQTL 2.68e-01 0.0609 0.0548 0.44 Other_T L1
ENSG00000136048 DRAM1 -394012 sc-eQTL 3.87e-01 -0.057 0.0658 0.44 Other_T L1
ENSG00000185480 PARPBP -636617 sc-eQTL 4.45e-01 0.042 0.0549 0.44 Other_T L1
ENSG00000281344 HELLPAR -714017 sc-eQTL 2.41e-01 -0.0749 0.0637 0.44 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000017427 IGF1 -998176 sc-eQTL 7.58e-01 0.00541 0.0175 0.457 B_Activated L2
ENSG00000075188 NUP37 -636552 sc-eQTL 7.24e-01 -0.0321 0.0908 0.457 B_Activated L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 6.87e-01 0.0271 0.0671 0.457 B_Activated L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 5.19e-01 -0.0615 0.0953 0.457 B_Activated L2
ENSG00000120800 UTP20 203463 sc-eQTL 8.18e-02 -0.16 0.0915 0.457 B_Activated L2
ENSG00000120805 ARL1 75796 sc-eQTL 9.42e-01 -0.00693 0.0953 0.457 B_Activated L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 7.88e-01 -0.0244 0.0908 0.457 B_Activated L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 1.06e-01 0.147 0.0905 0.457 B_Activated L2
ENSG00000139351 SYCP3 -255904 sc-eQTL 3.38e-01 -0.0718 0.0747 0.457 B_Activated L2
ENSG00000185480 PARPBP -636617 sc-eQTL 3.72e-01 -0.0673 0.0752 0.457 B_Activated L2
ENSG00000281344 HELLPAR -714017 sc-eQTL 3.54e-01 -0.0656 0.0707 0.457 B_Activated L2
ENSG00000017427 IGF1 -998176 sc-eQTL 5.30e-01 -0.0225 0.0358 0.438 B_Intermediate L2
ENSG00000075188 NUP37 -636552 sc-eQTL 4.63e-01 0.0656 0.0892 0.438 B_Intermediate L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 9.42e-01 -0.00348 0.0479 0.438 B_Intermediate L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 9.45e-01 0.00492 0.0708 0.438 B_Intermediate L2
ENSG00000120800 UTP20 203463 sc-eQTL 1.23e-01 -0.121 0.0783 0.438 B_Intermediate L2
ENSG00000120805 ARL1 75796 sc-eQTL 1.98e-01 0.114 0.0882 0.438 B_Intermediate L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 8.98e-01 0.00937 0.0732 0.438 B_Intermediate L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 2.30e-01 0.0941 0.0783 0.438 B_Intermediate L2
ENSG00000139351 SYCP3 -255904 sc-eQTL 4.73e-01 0.0593 0.0825 0.438 B_Intermediate L2
ENSG00000185480 PARPBP -636617 sc-eQTL 9.50e-01 0.00545 0.0867 0.438 B_Intermediate L2
ENSG00000281344 HELLPAR -714017 sc-eQTL 5.17e-01 0.0539 0.083 0.438 B_Intermediate L2
ENSG00000017427 IGF1 -998176 sc-eQTL 1.01e-01 -0.0534 0.0324 0.444 B_Memory L2
ENSG00000075188 NUP37 -636552 sc-eQTL 3.86e-01 0.0747 0.0861 0.444 B_Memory L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 8.94e-02 -0.0954 0.0559 0.444 B_Memory L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 9.72e-01 -0.00267 0.0771 0.444 B_Memory L2
ENSG00000120800 UTP20 203463 sc-eQTL 6.54e-01 -0.0379 0.0846 0.444 B_Memory L2
ENSG00000120805 ARL1 75796 sc-eQTL 6.81e-01 -0.0346 0.0841 0.444 B_Memory L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 7.31e-01 -0.0259 0.0752 0.444 B_Memory L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 7.29e-01 -0.0274 0.0789 0.444 B_Memory L2
ENSG00000139351 SYCP3 -255904 sc-eQTL 7.91e-01 -0.0215 0.0812 0.444 B_Memory L2
ENSG00000185480 PARPBP -636617 sc-eQTL 1.48e-01 -0.12 0.0827 0.444 B_Memory L2
ENSG00000281344 HELLPAR -714017 sc-eQTL 5.80e-01 0.0419 0.0756 0.444 B_Memory L2
ENSG00000017427 IGF1 -998176 sc-eQTL 9.63e-01 -0.00211 0.045 0.44 B_Naive1 L2
ENSG00000075188 NUP37 -636552 sc-eQTL 8.39e-01 0.0166 0.0815 0.44 B_Naive1 L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 8.76e-01 -0.00663 0.0424 0.44 B_Naive1 L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 6.31e-01 0.0288 0.0599 0.44 B_Naive1 L2
ENSG00000120800 UTP20 203463 sc-eQTL 2.46e-01 -0.0825 0.0709 0.44 B_Naive1 L2
ENSG00000120805 ARL1 75796 sc-eQTL 2.29e-01 -0.0955 0.0791 0.44 B_Naive1 L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 4.34e-01 -0.047 0.06 0.44 B_Naive1 L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 8.15e-01 0.0152 0.0651 0.44 B_Naive1 L2
ENSG00000139351 SYCP3 -255904 sc-eQTL 9.84e-01 -0.00181 0.0885 0.44 B_Naive1 L2
ENSG00000185480 PARPBP -636617 sc-eQTL 4.35e-01 -0.0672 0.086 0.44 B_Naive1 L2
ENSG00000281344 HELLPAR -714017 sc-eQTL 2.24e-02 -0.183 0.0797 0.44 B_Naive1 L2
ENSG00000017427 IGF1 -998176 sc-eQTL 8.59e-02 0.068 0.0394 0.442 B_Naive2 L2
ENSG00000075188 NUP37 -636552 sc-eQTL 6.35e-01 -0.0386 0.0813 0.442 B_Naive2 L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 4.64e-01 -0.0319 0.0435 0.442 B_Naive2 L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 9.65e-01 -0.00299 0.0675 0.442 B_Naive2 L2
ENSG00000120800 UTP20 203463 sc-eQTL 4.68e-01 -0.0567 0.0781 0.442 B_Naive2 L2
ENSG00000120805 ARL1 75796 sc-eQTL 2.13e-02 -0.197 0.0848 0.442 B_Naive2 L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 3.39e-01 -0.0715 0.0746 0.442 B_Naive2 L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 1.40e-01 0.109 0.0737 0.442 B_Naive2 L2
ENSG00000139351 SYCP3 -255904 sc-eQTL 5.53e-01 -0.0463 0.0779 0.442 B_Naive2 L2
ENSG00000185480 PARPBP -636617 sc-eQTL 4.47e-01 0.0684 0.0898 0.442 B_Naive2 L2
ENSG00000281344 HELLPAR -714017 sc-eQTL 4.85e-02 0.152 0.0768 0.442 B_Naive2 L2
ENSG00000075188 NUP37 -636552 sc-eQTL 2.28e-01 0.106 0.0876 0.448 CD4_CTL L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 1.20e-01 -0.137 0.0876 0.448 CD4_CTL L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 1.97e-01 0.0994 0.0767 0.448 CD4_CTL L2
ENSG00000120800 UTP20 203463 sc-eQTL 2.18e-01 -0.104 0.0844 0.448 CD4_CTL L2
ENSG00000120805 ARL1 75796 sc-eQTL 9.14e-01 -0.00966 0.0898 0.448 CD4_CTL L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 2.90e-01 0.0911 0.0859 0.448 CD4_CTL L2
ENSG00000075188 NUP37 -636552 sc-eQTL 2.32e-01 -0.0772 0.0644 0.44 CD4_Naive L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 1.05e-04 -0.284 0.0719 0.44 CD4_Naive L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 3.70e-02 0.119 0.0569 0.44 CD4_Naive L2
ENSG00000120800 UTP20 203463 sc-eQTL 1.62e-01 -0.0874 0.0623 0.44 CD4_Naive L2
ENSG00000120805 ARL1 75796 sc-eQTL 4.14e-01 0.0554 0.0677 0.44 CD4_Naive L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 7.59e-01 -0.0146 0.0474 0.44 CD4_Naive L2
ENSG00000075188 NUP37 -636552 sc-eQTL 9.40e-01 -0.0051 0.0679 0.44 CD4_TCM L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 4.06e-03 -0.223 0.0768 0.44 CD4_TCM L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 5.61e-01 0.0353 0.0606 0.44 CD4_TCM L2
ENSG00000120800 UTP20 203463 sc-eQTL 9.09e-01 -0.00865 0.0758 0.44 CD4_TCM L2
ENSG00000120805 ARL1 75796 sc-eQTL 3.42e-01 -0.0674 0.0708 0.44 CD4_TCM L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 7.90e-02 -0.0816 0.0462 0.44 CD4_TCM L2
ENSG00000075188 NUP37 -636552 sc-eQTL 8.51e-01 -0.0152 0.0811 0.44 CD4_TEM L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 2.82e-03 -0.231 0.0764 0.44 CD4_TEM L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 3.07e-01 0.0768 0.075 0.44 CD4_TEM L2
ENSG00000120800 UTP20 203463 sc-eQTL 5.70e-01 0.0463 0.0813 0.44 CD4_TEM L2
ENSG00000120805 ARL1 75796 sc-eQTL 7.18e-01 0.0278 0.0768 0.44 CD4_TEM L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 6.02e-01 -0.0359 0.0688 0.44 CD4_TEM L2
ENSG00000075188 NUP37 -636552 sc-eQTL 5.77e-01 -0.0422 0.0754 0.44 CD8_CTL L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 2.93e-03 -0.228 0.0758 0.44 CD8_CTL L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 9.83e-01 -0.00131 0.0619 0.44 CD8_CTL L2
ENSG00000120800 UTP20 203463 sc-eQTL 5.19e-01 0.054 0.0837 0.44 CD8_CTL L2
ENSG00000120805 ARL1 75796 sc-eQTL 1.88e-01 0.109 0.0825 0.44 CD8_CTL L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 3.52e-01 -0.0658 0.0705 0.44 CD8_CTL L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 1.86e-01 -0.116 0.0875 0.44 CD8_CTL L2
ENSG00000075188 NUP37 -636552 sc-eQTL 7.58e-01 -0.0245 0.0793 0.44 CD8_Naive L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 1.81e-02 -0.185 0.0778 0.44 CD8_Naive L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 9.18e-01 0.0073 0.0708 0.44 CD8_Naive L2
ENSG00000120800 UTP20 203463 sc-eQTL 5.13e-01 0.0493 0.0752 0.44 CD8_Naive L2
ENSG00000120805 ARL1 75796 sc-eQTL 5.69e-01 0.0466 0.0817 0.44 CD8_Naive L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 8.52e-01 -0.0101 0.0538 0.44 CD8_Naive L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 3.19e-01 0.0828 0.0829 0.44 CD8_Naive L2
ENSG00000075188 NUP37 -636552 sc-eQTL 8.06e-01 0.021 0.0853 0.451 CD8_TCM L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 7.40e-03 -0.203 0.0751 0.451 CD8_TCM L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 4.33e-02 0.159 0.0784 0.451 CD8_TCM L2
ENSG00000120800 UTP20 203463 sc-eQTL 4.12e-01 -0.0709 0.0862 0.451 CD8_TCM L2
ENSG00000120805 ARL1 75796 sc-eQTL 3.15e-01 0.0852 0.0846 0.451 CD8_TCM L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 4.22e-01 -0.0611 0.0758 0.451 CD8_TCM L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 6.52e-01 0.0374 0.0828 0.451 CD8_TCM L2
ENSG00000075188 NUP37 -636552 sc-eQTL 8.11e-01 0.0207 0.0865 0.434 CD8_TEM L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 2.42e-01 -0.0956 0.0815 0.434 CD8_TEM L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 8.38e-01 0.0179 0.0876 0.434 CD8_TEM L2
ENSG00000120800 UTP20 203463 sc-eQTL 9.30e-01 0.00827 0.094 0.434 CD8_TEM L2
ENSG00000120805 ARL1 75796 sc-eQTL 7.06e-01 -0.0339 0.0898 0.434 CD8_TEM L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 1.67e-01 -0.108 0.0782 0.434 CD8_TEM L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 6.34e-01 -0.0413 0.0866 0.434 CD8_TEM L2
ENSG00000017427 IGF1 -998176 sc-eQTL 5.47e-02 0.0565 0.0292 0.442 MAIT L2
ENSG00000075188 NUP37 -636552 sc-eQTL 4.05e-01 0.069 0.0826 0.442 MAIT L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 2.10e-01 -0.101 0.0803 0.442 MAIT L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 1.72e-01 0.0975 0.0712 0.442 MAIT L2
ENSG00000120800 UTP20 203463 sc-eQTL 7.29e-02 -0.153 0.085 0.442 MAIT L2
ENSG00000120805 ARL1 75796 sc-eQTL 2.09e-01 -0.11 0.0871 0.442 MAIT L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 9.21e-01 -0.00719 0.0727 0.442 MAIT L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 4.69e-01 0.0597 0.0823 0.442 MAIT L2
ENSG00000185480 PARPBP -636617 sc-eQTL 3.73e-01 0.0719 0.0806 0.442 MAIT L2
ENSG00000281344 HELLPAR -714017 sc-eQTL 7.37e-01 -0.024 0.0715 0.442 MAIT L2
ENSG00000075188 NUP37 -636552 sc-eQTL 6.89e-01 0.0366 0.0914 0.438 NK_CD56bright L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 6.23e-02 -0.123 0.0656 0.438 NK_CD56bright L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 6.41e-01 -0.0357 0.0764 0.438 NK_CD56bright L2
ENSG00000120800 UTP20 203463 sc-eQTL 9.58e-01 -0.00476 0.0892 0.438 NK_CD56bright L2
ENSG00000120805 ARL1 75796 sc-eQTL 7.17e-01 -0.0316 0.0872 0.438 NK_CD56bright L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 1.58e-01 0.111 0.0784 0.438 NK_CD56bright L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 3.40e-02 0.175 0.082 0.438 NK_CD56bright L2
ENSG00000185480 PARPBP -636617 sc-eQTL 7.96e-01 0.0227 0.0875 0.438 NK_CD56bright L2
ENSG00000075188 NUP37 -636552 sc-eQTL 8.82e-01 -0.0117 0.0782 0.435 NK_CD56dim L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 3.86e-03 -0.219 0.0749 0.435 NK_CD56dim L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 6.21e-01 -0.0286 0.0578 0.435 NK_CD56dim L2
ENSG00000120800 UTP20 203463 sc-eQTL 3.68e-01 -0.0723 0.0801 0.435 NK_CD56dim L2
ENSG00000120805 ARL1 75796 sc-eQTL 1.92e-01 -0.101 0.0773 0.435 NK_CD56dim L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 3.76e-01 -0.0589 0.0664 0.435 NK_CD56dim L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 9.98e-02 0.133 0.0802 0.435 NK_CD56dim L2
ENSG00000185480 PARPBP -636617 sc-eQTL 2.98e-01 0.0947 0.0907 0.435 NK_CD56dim L2
ENSG00000075188 NUP37 -636552 sc-eQTL 6.33e-01 0.0396 0.0828 0.438 NK_HLA L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 1.88e-01 -0.112 0.0847 0.438 NK_HLA L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 8.10e-01 -0.0164 0.0683 0.438 NK_HLA L2
ENSG00000120800 UTP20 203463 sc-eQTL 3.68e-01 -0.0805 0.0892 0.438 NK_HLA L2
ENSG00000120805 ARL1 75796 sc-eQTL 2.65e-02 0.201 0.0902 0.438 NK_HLA L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 7.53e-01 -0.0267 0.0848 0.438 NK_HLA L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 3.92e-01 0.0747 0.087 0.438 NK_HLA L2
ENSG00000185480 PARPBP -636617 sc-eQTL 6.82e-01 -0.0352 0.0857 0.438 NK_HLA L2
ENSG00000075188 NUP37 -636552 sc-eQTL 8.62e-01 -0.0138 0.0794 0.435 NK_cytokine L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 4.40e-02 -0.149 0.0736 0.435 NK_cytokine L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 5.80e-01 0.0313 0.0564 0.435 NK_cytokine L2
ENSG00000120800 UTP20 203463 sc-eQTL 8.12e-01 0.0188 0.0787 0.435 NK_cytokine L2
ENSG00000120805 ARL1 75796 sc-eQTL 1.00e-01 0.13 0.0787 0.435 NK_cytokine L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 8.19e-02 -0.108 0.0619 0.435 NK_cytokine L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 2.15e-01 0.101 0.0809 0.435 NK_cytokine L2
ENSG00000185480 PARPBP -636617 sc-eQTL 4.70e-01 -0.0635 0.0876 0.435 NK_cytokine L2
ENSG00000017427 IGF1 -998176 sc-eQTL 8.96e-01 0.00827 0.0631 0.433 PB L2
ENSG00000075188 NUP37 -636552 sc-eQTL 1.76e-01 -0.115 0.0843 0.433 PB L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 2.68e-01 0.0729 0.0656 0.433 PB L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 2.17e-01 0.117 0.0941 0.433 PB L2
ENSG00000120800 UTP20 203463 sc-eQTL 6.22e-01 -0.0538 0.109 0.433 PB L2
ENSG00000120805 ARL1 75796 sc-eQTL 5.68e-01 0.0383 0.0668 0.433 PB L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 2.20e-01 0.0946 0.0767 0.433 PB L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 1.05e-01 0.126 0.0774 0.433 PB L2
ENSG00000139351 SYCP3 -255904 sc-eQTL 1.04e-01 -0.147 0.0899 0.433 PB L2
ENSG00000185480 PARPBP -636617 sc-eQTL 2.76e-01 -0.0907 0.0829 0.433 PB L2
ENSG00000281344 HELLPAR -714017 sc-eQTL 3.87e-01 0.0667 0.0769 0.433 PB L2
ENSG00000017427 IGF1 -998176 sc-eQTL 5.78e-01 0.0162 0.0291 0.441 Pro_T L2
ENSG00000075188 NUP37 -636552 sc-eQTL 4.43e-01 -0.0451 0.0586 0.441 Pro_T L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 4.21e-01 -0.0626 0.0777 0.441 Pro_T L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 1.36e-01 0.0857 0.0573 0.441 Pro_T L2
ENSG00000120800 UTP20 203463 sc-eQTL 7.20e-01 -0.0295 0.0822 0.441 Pro_T L2
ENSG00000120805 ARL1 75796 sc-eQTL 4.97e-01 0.0422 0.0621 0.441 Pro_T L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 2.64e-01 0.0755 0.0674 0.441 Pro_T L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 1.55e-02 0.139 0.0571 0.441 Pro_T L2
ENSG00000185480 PARPBP -636617 sc-eQTL 5.87e-01 0.0292 0.0537 0.441 Pro_T L2
ENSG00000281344 HELLPAR -714017 sc-eQTL 3.13e-03 -0.172 0.0575 0.441 Pro_T L2
ENSG00000075188 NUP37 -636552 sc-eQTL 3.89e-01 0.0718 0.0832 0.44 Treg L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 2.41e-03 -0.261 0.0848 0.44 Treg L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 2.43e-01 -0.0885 0.0755 0.44 Treg L2
ENSG00000120800 UTP20 203463 sc-eQTL 7.58e-02 0.146 0.0819 0.44 Treg L2
ENSG00000120805 ARL1 75796 sc-eQTL 7.99e-01 -0.0218 0.0853 0.44 Treg L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 9.34e-01 0.00577 0.0693 0.44 Treg L2
ENSG00000075188 NUP37 -636552 sc-eQTL 3.72e-01 0.0691 0.0773 0.441 cDC L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 2.03e-02 -0.174 0.0745 0.441 cDC L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 2.35e-01 0.116 0.0971 0.441 cDC L2
ENSG00000120800 UTP20 203463 sc-eQTL 3.24e-01 0.0871 0.0881 0.441 cDC L2
ENSG00000120805 ARL1 75796 sc-eQTL 9.12e-01 0.0101 0.0916 0.441 cDC L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 4.89e-01 -0.0596 0.0859 0.441 cDC L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 6.05e-01 -0.0347 0.067 0.441 cDC L2
ENSG00000139354 GAS2L3 909885 sc-eQTL 1.94e-01 0.106 0.0816 0.441 cDC L2
ENSG00000185480 PARPBP -636617 sc-eQTL 6.38e-01 -0.036 0.0764 0.441 cDC L2
ENSG00000075188 NUP37 -636552 sc-eQTL 1.29e-01 0.113 0.0742 0.44 cMono_IL1B L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 2.66e-01 -0.0626 0.0561 0.44 cMono_IL1B L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 4.68e-01 -0.0542 0.0746 0.44 cMono_IL1B L2
ENSG00000120800 UTP20 203463 sc-eQTL 3.69e-01 0.0755 0.0838 0.44 cMono_IL1B L2
ENSG00000120805 ARL1 75796 sc-eQTL 1.24e-01 0.115 0.0748 0.44 cMono_IL1B L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 2.64e-01 -0.0725 0.0647 0.44 cMono_IL1B L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 4.54e-01 0.0415 0.0552 0.44 cMono_IL1B L2
ENSG00000139354 GAS2L3 909885 sc-eQTL 2.40e-01 0.0711 0.0603 0.44 cMono_IL1B L2
ENSG00000075188 NUP37 -636552 sc-eQTL 4.50e-01 0.0618 0.0817 0.44 cMono_S100A L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 5.30e-01 -0.0394 0.0626 0.44 cMono_S100A L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 1.42e-01 0.112 0.0759 0.44 cMono_S100A L2
ENSG00000120800 UTP20 203463 sc-eQTL 2.57e-01 0.101 0.0891 0.44 cMono_S100A L2
ENSG00000120805 ARL1 75796 sc-eQTL 4.87e-01 0.0584 0.0839 0.44 cMono_S100A L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 6.78e-01 0.0322 0.0776 0.44 cMono_S100A L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 8.30e-01 -0.013 0.0605 0.44 cMono_S100A L2
ENSG00000139354 GAS2L3 909885 sc-eQTL 6.83e-02 0.138 0.0752 0.44 cMono_S100A L2
ENSG00000075188 NUP37 -636552 sc-eQTL 6.72e-01 0.0457 0.108 0.433 gdT L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 3.46e-02 -0.212 0.0995 0.433 gdT L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 5.04e-01 0.0509 0.076 0.433 gdT L2
ENSG00000120800 UTP20 203463 sc-eQTL 3.32e-01 -0.0976 0.1 0.433 gdT L2
ENSG00000120805 ARL1 75796 sc-eQTL 6.31e-01 -0.0507 0.105 0.433 gdT L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 3.89e-01 -0.0847 0.0981 0.433 gdT L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 2.01e-02 -0.23 0.098 0.433 gdT L2
ENSG00000185480 PARPBP -636617 sc-eQTL 3.79e-03 0.28 0.0953 0.433 gdT L2
ENSG00000281344 HELLPAR -714017 sc-eQTL 2.23e-01 0.11 0.0894 0.433 gdT L2
ENSG00000075188 NUP37 -636552 sc-eQTL 5.34e-01 0.0504 0.0808 0.433 intMono L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 9.56e-01 0.00412 0.0739 0.433 intMono L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 4.65e-02 -0.172 0.086 0.433 intMono L2
ENSG00000120800 UTP20 203463 sc-eQTL 5.43e-01 0.0495 0.0812 0.433 intMono L2
ENSG00000120805 ARL1 75796 sc-eQTL 8.30e-01 0.0181 0.0841 0.433 intMono L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 9.14e-01 0.00876 0.0813 0.433 intMono L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 5.56e-01 -0.0418 0.071 0.433 intMono L2
ENSG00000139354 GAS2L3 909885 sc-eQTL 2.25e-01 0.0954 0.0784 0.433 intMono L2
ENSG00000075188 NUP37 -636552 sc-eQTL 8.57e-01 -0.0151 0.0839 0.43 ncMono L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 1.40e-01 -0.114 0.077 0.43 ncMono L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 6.35e-01 -0.0441 0.0927 0.43 ncMono L2
ENSG00000120800 UTP20 203463 sc-eQTL 6.74e-02 0.148 0.0804 0.43 ncMono L2
ENSG00000120805 ARL1 75796 sc-eQTL 8.93e-01 0.0105 0.078 0.43 ncMono L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 7.04e-01 -0.0285 0.0749 0.43 ncMono L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 1.54e-01 0.0993 0.0694 0.43 ncMono L2
ENSG00000139354 GAS2L3 909885 sc-eQTL 3.36e-01 0.0698 0.0724 0.43 ncMono L2
ENSG00000075188 NUP37 -636552 sc-eQTL 7.77e-01 0.0291 0.103 0.449 pDC L2
ENSG00000111666 CHPT1 -213379 sc-eQTL 2.68e-01 -0.0991 0.0891 0.449 pDC L2
ENSG00000111670 GNPTAB -347391 sc-eQTL 8.83e-01 -0.014 0.0947 0.449 pDC L2
ENSG00000120800 UTP20 203463 sc-eQTL 2.76e-01 0.103 0.094 0.449 pDC L2
ENSG00000120805 ARL1 75796 sc-eQTL 1.39e-01 -0.146 0.0985 0.449 pDC L2
ENSG00000120860 WASHC3 -578581 sc-eQTL 8.51e-01 -0.0162 0.0865 0.449 pDC L2
ENSG00000136048 DRAM1 -394012 sc-eQTL 7.72e-02 -0.118 0.0662 0.449 pDC L2
ENSG00000139354 GAS2L3 909885 sc-eQTL 7.75e-01 -0.0229 0.0799 0.449 pDC L2
ENSG00000185480 PARPBP -636617 sc-eQTL 8.23e-01 0.02 0.0888 0.449 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000017427 IGF1 -998176 sc-eQTL 5.15e-01 -0.0269 0.0413 0.44 B_Memory LOneK1K
ENSG00000075188 NUP37 -636552 sc-eQTL 4.55e-01 0.0621 0.0829 0.44 B_Memory LOneK1K
ENSG00000111666 CHPT1 -213379 sc-eQTL 8.01e-01 -0.011 0.0436 0.44 B_Memory LOneK1K
ENSG00000111670 GNPTAB -347391 sc-eQTL 8.64e-01 -0.0117 0.0686 0.44 B_Memory LOneK1K
ENSG00000120800 UTP20 203463 sc-eQTL 1.87e-01 -0.0931 0.0704 0.44 B_Memory LOneK1K
ENSG00000120805 ARL1 75796 sc-eQTL 3.45e-01 0.0754 0.0797 0.44 B_Memory LOneK1K
ENSG00000120860 WASHC3 -578581 sc-eQTL 8.16e-01 0.0139 0.0597 0.44 B_Memory LOneK1K
ENSG00000136048 DRAM1 -394012 sc-eQTL 1.64e-01 0.0993 0.0711 0.44 B_Memory LOneK1K
ENSG00000139351 SYCP3 -255904 sc-eQTL 5.73e-01 0.0464 0.0823 0.44 B_Memory LOneK1K
ENSG00000185480 PARPBP -636617 sc-eQTL 7.51e-01 -0.0274 0.0862 0.44 B_Memory LOneK1K
ENSG00000281344 HELLPAR -714017 sc-eQTL 3.45e-01 0.0806 0.0853 0.44 B_Memory LOneK1K
ENSG00000017427 IGF1 -998176 sc-eQTL 8.43e-01 0.00946 0.0477 0.44 B_Naive LOneK1K
ENSG00000075188 NUP37 -636552 sc-eQTL 9.92e-01 -0.000751 0.078 0.44 B_Naive LOneK1K
ENSG00000111666 CHPT1 -213379 sc-eQTL 7.50e-01 -0.0123 0.0385 0.44 B_Naive LOneK1K
ENSG00000111670 GNPTAB -347391 sc-eQTL 7.82e-01 0.0153 0.0552 0.44 B_Naive LOneK1K
ENSG00000120800 UTP20 203463 sc-eQTL 3.00e-01 -0.07 0.0674 0.44 B_Naive LOneK1K
ENSG00000120805 ARL1 75796 sc-eQTL 4.40e-02 -0.155 0.0763 0.44 B_Naive LOneK1K
ENSG00000120860 WASHC3 -578581 sc-eQTL 2.11e-01 -0.0722 0.0575 0.44 B_Naive LOneK1K
ENSG00000136048 DRAM1 -394012 sc-eQTL 3.85e-01 0.0526 0.0604 0.44 B_Naive LOneK1K
ENSG00000139351 SYCP3 -255904 sc-eQTL 7.73e-01 -0.0252 0.0873 0.44 B_Naive LOneK1K
ENSG00000185480 PARPBP -636617 sc-eQTL 5.09e-01 -0.0588 0.0888 0.44 B_Naive LOneK1K
ENSG00000281344 HELLPAR -714017 sc-eQTL 6.51e-01 -0.0367 0.0809 0.44 B_Naive LOneK1K
ENSG00000075188 NUP37 -636552 sc-eQTL 1.39e-01 0.102 0.0689 0.44 CD14_Mono LOneK1K
ENSG00000111666 CHPT1 -213379 sc-eQTL 3.17e-01 -0.056 0.0559 0.44 CD14_Mono LOneK1K
ENSG00000111670 GNPTAB -347391 sc-eQTL 6.95e-01 0.0283 0.072 0.44 CD14_Mono LOneK1K
ENSG00000120800 UTP20 203463 sc-eQTL 1.61e-01 0.119 0.0848 0.44 CD14_Mono LOneK1K
ENSG00000120805 ARL1 75796 sc-eQTL 8.63e-02 0.125 0.0724 0.44 CD14_Mono LOneK1K
ENSG00000120860 WASHC3 -578581 sc-eQTL 6.46e-01 -0.0292 0.0634 0.44 CD14_Mono LOneK1K
ENSG00000136048 DRAM1 -394012 sc-eQTL 4.30e-01 0.041 0.0519 0.44 CD14_Mono LOneK1K
ENSG00000139354 GAS2L3 909885 sc-eQTL 1.08e-01 0.0959 0.0594 0.44 CD14_Mono LOneK1K
ENSG00000075188 NUP37 -636552 sc-eQTL 9.18e-01 0.00819 0.0795 0.435 CD16_Mono LOneK1K
ENSG00000111666 CHPT1 -213379 sc-eQTL 6.36e-01 -0.0328 0.0694 0.435 CD16_Mono LOneK1K
ENSG00000111670 GNPTAB -347391 sc-eQTL 2.33e-01 -0.1 0.0837 0.435 CD16_Mono LOneK1K
ENSG00000120800 UTP20 203463 sc-eQTL 1.70e-01 0.111 0.0805 0.435 CD16_Mono LOneK1K
ENSG00000120805 ARL1 75796 sc-eQTL 7.14e-01 0.0294 0.0803 0.435 CD16_Mono LOneK1K
ENSG00000120860 WASHC3 -578581 sc-eQTL 3.48e-01 -0.0654 0.0695 0.435 CD16_Mono LOneK1K
ENSG00000136048 DRAM1 -394012 sc-eQTL 6.81e-01 0.0247 0.0601 0.435 CD16_Mono LOneK1K
ENSG00000139354 GAS2L3 909885 sc-eQTL 1.74e-01 0.0995 0.073 0.435 CD16_Mono LOneK1K
ENSG00000075188 NUP37 -636552 sc-eQTL 7.81e-01 0.0208 0.0749 0.435 NK_CD56dim LOneK1K
ENSG00000111666 CHPT1 -213379 sc-eQTL 5.34e-03 -0.202 0.0717 0.435 NK_CD56dim LOneK1K
ENSG00000111670 GNPTAB -347391 sc-eQTL 7.21e-01 -0.0179 0.05 0.435 NK_CD56dim LOneK1K
ENSG00000120800 UTP20 203463 sc-eQTL 6.44e-01 -0.0355 0.0767 0.435 NK_CD56dim LOneK1K
ENSG00000120805 ARL1 75796 sc-eQTL 5.89e-01 0.0385 0.0712 0.435 NK_CD56dim LOneK1K
ENSG00000120860 WASHC3 -578581 sc-eQTL 1.08e-01 -0.0925 0.0573 0.435 NK_CD56dim LOneK1K
ENSG00000136048 DRAM1 -394012 sc-eQTL 7.11e-02 0.139 0.0769 0.435 NK_CD56dim LOneK1K
ENSG00000185480 PARPBP -636617 sc-eQTL 6.26e-01 0.0444 0.0911 0.435 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000111666 CHPT1 -213379 eQTL 6.54e-04 -0.086 0.0251 0.0 0.0 0.43
ENSG00000120860 WASHC3 -578581 pQTL 0.00156 -0.0293 0.00925 0.0 0.00123 0.445

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000111666 CHPT1 -213379 2.11e-06 2.43e-06 3.23e-07 1.69e-06 4.67e-07 7.84e-07 1.36e-06 6.39e-07 1.74e-06 8.25e-07 1.97e-06 1.34e-06 3.5e-06 1.04e-06 6.96e-07 1.53e-06 9.67e-07 1.92e-06 8.58e-07 1.19e-06 9.86e-07 2.57e-06 2.04e-06 1.08e-06 2.86e-06 1.37e-06 1.22e-06 1.45e-06 1.86e-06 1.66e-06 1.15e-06 3.1e-07 5.19e-07 1.2e-06 1.07e-06 9.73e-07 8.28e-07 4.12e-07 1.12e-06 3.97e-07 1.96e-07 2.83e-06 4.16e-07 2.15e-07 2.94e-07 2.95e-07 7.57e-07 2.44e-07 2.05e-07