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Genes within 1Mb (chr1:74691589:C:T):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -41819 sc-eQTL 9.45e-01 -0.00642 0.0927 0.865 B L1
ENSG00000162623 TYW3 -41563 sc-eQTL 1.39e-03 -0.412 0.127 0.865 B L1
ENSG00000254685 FPGT 493377 sc-eQTL 4.36e-01 0.104 0.133 0.865 B L1
ENSG00000116791 CRYZ -41819 sc-eQTL 5.36e-01 -0.0591 0.0952 0.865 CD4T L1
ENSG00000162623 TYW3 -41563 sc-eQTL 4.07e-01 -0.0943 0.113 0.865 CD4T L1
ENSG00000254685 FPGT 493377 sc-eQTL 1.29e-01 0.171 0.112 0.865 CD4T L1
ENSG00000116791 CRYZ -41819 sc-eQTL 3.87e-01 -0.0859 0.0992 0.865 CD8T L1
ENSG00000162623 TYW3 -41563 sc-eQTL 5.00e-01 -0.0825 0.122 0.865 CD8T L1
ENSG00000254685 FPGT 493377 sc-eQTL 2.93e-01 0.141 0.134 0.865 CD8T L1
ENSG00000116791 CRYZ -41819 sc-eQTL 1.15e-01 -0.221 0.14 0.867 DC L1
ENSG00000162623 TYW3 -41563 sc-eQTL 8.11e-01 -0.0332 0.139 0.867 DC L1
ENSG00000254685 FPGT 493377 sc-eQTL 6.40e-02 0.263 0.141 0.867 DC L1
ENSG00000116791 CRYZ -41819 sc-eQTL 6.72e-01 -0.0631 0.149 0.865 Mono L1
ENSG00000162623 TYW3 -41563 sc-eQTL 6.14e-01 -0.0682 0.135 0.865 Mono L1
ENSG00000254685 FPGT 493377 sc-eQTL 9.57e-01 -0.00622 0.115 0.865 Mono L1
ENSG00000116791 CRYZ -41819 sc-eQTL 4.72e-01 -0.0768 0.107 0.869 NK L1
ENSG00000162623 TYW3 -41563 sc-eQTL 3.08e-01 0.13 0.127 0.869 NK L1
ENSG00000254685 FPGT 493377 sc-eQTL 1.98e-01 0.165 0.128 0.869 NK L1
ENSG00000116791 CRYZ -41819 sc-eQTL 8.50e-01 0.0239 0.127 0.865 Other_T L1
ENSG00000162623 TYW3 -41563 sc-eQTL 4.74e-01 -0.0809 0.113 0.865 Other_T L1
ENSG00000254685 FPGT 493377 sc-eQTL 1.50e-01 -0.198 0.137 0.865 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -41819 sc-eQTL 4.25e-01 -0.121 0.151 0.862 B_Activated L2
ENSG00000162623 TYW3 -41563 sc-eQTL 9.94e-01 0.00119 0.16 0.862 B_Activated L2
ENSG00000254685 FPGT 493377 sc-eQTL 8.58e-01 -0.026 0.145 0.862 B_Activated L2
ENSG00000116791 CRYZ -41819 sc-eQTL 6.70e-01 0.0479 0.112 0.865 B_Intermediate L2
ENSG00000162623 TYW3 -41563 sc-eQTL 1.52e-01 -0.212 0.148 0.865 B_Intermediate L2
ENSG00000254685 FPGT 493377 sc-eQTL 2.00e-01 0.177 0.138 0.865 B_Intermediate L2
ENSG00000116791 CRYZ -41819 sc-eQTL 7.84e-01 -0.0331 0.121 0.866 B_Memory L2
ENSG00000162623 TYW3 -41563 sc-eQTL 2.49e-01 -0.165 0.143 0.866 B_Memory L2
ENSG00000254685 FPGT 493377 sc-eQTL 8.02e-01 0.0363 0.145 0.866 B_Memory L2
ENSG00000116791 CRYZ -41819 sc-eQTL 2.63e-01 0.135 0.121 0.865 B_Naive1 L2
ENSG00000162623 TYW3 -41563 sc-eQTL 3.37e-02 -0.313 0.146 0.865 B_Naive1 L2
ENSG00000254685 FPGT 493377 sc-eQTL 6.69e-01 -0.0592 0.138 0.865 B_Naive1 L2
ENSG00000116791 CRYZ -41819 sc-eQTL 5.17e-01 -0.0789 0.122 0.867 B_Naive2 L2
ENSG00000162623 TYW3 -41563 sc-eQTL 1.24e-02 -0.362 0.143 0.867 B_Naive2 L2
ENSG00000254685 FPGT 493377 sc-eQTL 9.18e-01 -0.0145 0.14 0.867 B_Naive2 L2
ENSG00000116791 CRYZ -41819 sc-eQTL 1.01e-02 0.355 0.137 0.868 CD4_CTL L2
ENSG00000162623 TYW3 -41563 sc-eQTL 2.88e-03 -0.433 0.144 0.868 CD4_CTL L2
ENSG00000254685 FPGT 493377 sc-eQTL 4.86e-01 0.0889 0.127 0.868 CD4_CTL L2
ENSG00000116791 CRYZ -41819 sc-eQTL 4.04e-01 -0.0889 0.106 0.865 CD4_Naive L2
ENSG00000162623 TYW3 -41563 sc-eQTL 4.52e-01 -0.0963 0.128 0.865 CD4_Naive L2
ENSG00000254685 FPGT 493377 sc-eQTL 1.42e-02 0.303 0.123 0.865 CD4_Naive L2
ENSG00000116791 CRYZ -41819 sc-eQTL 3.43e-01 -0.102 0.107 0.865 CD4_TCM L2
ENSG00000162623 TYW3 -41563 sc-eQTL 8.32e-01 -0.0287 0.135 0.865 CD4_TCM L2
ENSG00000254685 FPGT 493377 sc-eQTL 7.39e-01 0.0457 0.137 0.865 CD4_TCM L2
ENSG00000116791 CRYZ -41819 sc-eQTL 6.12e-01 -0.0642 0.126 0.865 CD4_TEM L2
ENSG00000162623 TYW3 -41563 sc-eQTL 7.44e-01 -0.0475 0.146 0.865 CD4_TEM L2
ENSG00000254685 FPGT 493377 sc-eQTL 5.15e-01 -0.0897 0.137 0.865 CD4_TEM L2
ENSG00000116791 CRYZ -41819 sc-eQTL 5.23e-01 -0.075 0.117 0.865 CD8_CTL L2
ENSG00000162623 TYW3 -41563 sc-eQTL 3.89e-01 -0.124 0.143 0.865 CD8_CTL L2
ENSG00000254685 FPGT 493377 sc-eQTL 7.32e-01 -0.0467 0.136 0.865 CD8_CTL L2
ENSG00000116791 CRYZ -41819 sc-eQTL 3.38e-01 -0.11 0.114 0.865 CD8_Naive L2
ENSG00000162623 TYW3 -41563 sc-eQTL 4.07e-01 0.107 0.128 0.865 CD8_Naive L2
ENSG00000254685 FPGT 493377 sc-eQTL 3.43e-01 0.128 0.135 0.865 CD8_Naive L2
ENSG00000116791 CRYZ -41819 sc-eQTL 5.32e-01 0.0822 0.131 0.866 CD8_TCM L2
ENSG00000162623 TYW3 -41563 sc-eQTL 2.42e-01 -0.177 0.151 0.866 CD8_TCM L2
ENSG00000254685 FPGT 493377 sc-eQTL 9.25e-01 -0.0129 0.137 0.866 CD8_TCM L2
ENSG00000116791 CRYZ -41819 sc-eQTL 1.41e-01 -0.203 0.137 0.863 CD8_TEM L2
ENSG00000162623 TYW3 -41563 sc-eQTL 7.12e-01 -0.0523 0.141 0.863 CD8_TEM L2
ENSG00000254685 FPGT 493377 sc-eQTL 5.19e-01 0.0824 0.128 0.863 CD8_TEM L2
ENSG00000116791 CRYZ -41819 sc-eQTL 6.28e-01 -0.0628 0.129 0.868 MAIT L2
ENSG00000162623 TYW3 -41563 sc-eQTL 4.97e-01 0.104 0.154 0.868 MAIT L2
ENSG00000254685 FPGT 493377 sc-eQTL 9.48e-01 -0.00866 0.132 0.868 MAIT L2
ENSG00000116791 CRYZ -41819 sc-eQTL 3.87e-01 -0.126 0.145 0.876 NK_CD56bright L2
ENSG00000162623 TYW3 -41563 sc-eQTL 7.76e-01 -0.0446 0.157 0.876 NK_CD56bright L2
ENSG00000254685 FPGT 493377 sc-eQTL 6.82e-01 -0.0562 0.137 0.876 NK_CD56bright L2
ENSG00000116791 CRYZ -41819 sc-eQTL 1.77e-01 -0.165 0.122 0.871 NK_CD56dim L2
ENSG00000162623 TYW3 -41563 sc-eQTL 5.33e-01 0.0861 0.138 0.871 NK_CD56dim L2
ENSG00000254685 FPGT 493377 sc-eQTL 7.65e-01 0.0424 0.142 0.871 NK_CD56dim L2
ENSG00000116791 CRYZ -41819 sc-eQTL 5.30e-01 -0.0911 0.145 0.868 NK_HLA L2
ENSG00000162623 TYW3 -41563 sc-eQTL 9.55e-01 0.00839 0.15 0.868 NK_HLA L2
ENSG00000254685 FPGT 493377 sc-eQTL 5.53e-01 0.0862 0.145 0.868 NK_HLA L2
ENSG00000116791 CRYZ -41819 sc-eQTL 4.10e-01 0.103 0.124 0.871 NK_cytokine L2
ENSG00000162623 TYW3 -41563 sc-eQTL 6.12e-01 0.069 0.136 0.871 NK_cytokine L2
ENSG00000254685 FPGT 493377 sc-eQTL 5.39e-02 0.256 0.132 0.871 NK_cytokine L2
ENSG00000116791 CRYZ -41819 sc-eQTL 8.04e-01 -0.0426 0.171 0.848 PB L2
ENSG00000162623 TYW3 -41563 sc-eQTL 8.52e-01 0.0309 0.165 0.848 PB L2
ENSG00000254685 FPGT 493377 sc-eQTL 3.68e-02 0.339 0.16 0.848 PB L2
ENSG00000116791 CRYZ -41819 sc-eQTL 9.18e-01 -0.0151 0.146 0.867 Pro_T L2
ENSG00000162623 TYW3 -41563 sc-eQTL 3.39e-01 -0.109 0.114 0.867 Pro_T L2
ENSG00000254685 FPGT 493377 sc-eQTL 5.56e-01 -0.0768 0.13 0.867 Pro_T L2
ENSG00000116791 CRYZ -41819 sc-eQTL 4.14e-01 0.111 0.135 0.865 Treg L2
ENSG00000162623 TYW3 -41563 sc-eQTL 1.55e-01 -0.195 0.137 0.865 Treg L2
ENSG00000254685 FPGT 493377 sc-eQTL 6.57e-01 -0.0598 0.134 0.865 Treg L2
ENSG00000116791 CRYZ -41819 sc-eQTL 2.35e-01 -0.173 0.145 0.868 cDC L2
ENSG00000162623 TYW3 -41563 sc-eQTL 5.14e-01 0.0957 0.146 0.868 cDC L2
ENSG00000254685 FPGT 493377 sc-eQTL 4.04e-02 0.307 0.149 0.868 cDC L2
ENSG00000116791 CRYZ -41819 sc-eQTL 8.12e-01 -0.0351 0.147 0.865 cMono_IL1B L2
ENSG00000162623 TYW3 -41563 sc-eQTL 3.09e-01 -0.143 0.14 0.865 cMono_IL1B L2
ENSG00000254685 FPGT 493377 sc-eQTL 8.96e-01 0.0174 0.133 0.865 cMono_IL1B L2
ENSG00000116791 CRYZ -41819 sc-eQTL 5.87e-01 -0.0781 0.144 0.865 cMono_S100A L2
ENSG00000162623 TYW3 -41563 sc-eQTL 9.27e-01 0.0135 0.146 0.865 cMono_S100A L2
ENSG00000254685 FPGT 493377 sc-eQTL 9.33e-01 0.011 0.131 0.865 cMono_S100A L2
ENSG00000116791 CRYZ -41819 sc-eQTL 9.34e-01 -0.0134 0.162 0.87 gdT L2
ENSG00000162623 TYW3 -41563 sc-eQTL 1.36e-01 -0.259 0.173 0.87 gdT L2
ENSG00000254685 FPGT 493377 sc-eQTL 7.93e-01 -0.0431 0.164 0.87 gdT L2
ENSG00000116791 CRYZ -41819 sc-eQTL 7.24e-02 -0.255 0.141 0.867 intMono L2
ENSG00000162623 TYW3 -41563 sc-eQTL 9.23e-01 0.015 0.155 0.867 intMono L2
ENSG00000254685 FPGT 493377 sc-eQTL 1.40e-01 -0.212 0.143 0.867 intMono L2
ENSG00000116791 CRYZ -41819 sc-eQTL 2.04e-01 -0.18 0.142 0.867 ncMono L2
ENSG00000162623 TYW3 -41563 sc-eQTL 8.68e-01 0.0263 0.159 0.867 ncMono L2
ENSG00000254685 FPGT 493377 sc-eQTL 3.97e-01 0.115 0.136 0.867 ncMono L2
ENSG00000116791 CRYZ -41819 sc-eQTL 5.87e-01 -0.085 0.156 0.867 pDC L2
ENSG00000162623 TYW3 -41563 sc-eQTL 3.84e-01 -0.134 0.154 0.867 pDC L2
ENSG00000254685 FPGT 493377 sc-eQTL 2.50e-01 0.165 0.142 0.867 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -41819 sc-eQTL 6.26e-01 0.0494 0.101 0.865 B_Memory LOneK1K
ENSG00000162623 TYW3 -41563 sc-eQTL 8.26e-02 -0.253 0.145 0.865 B_Memory LOneK1K
ENSG00000254685 FPGT 493377 sc-eQTL 4.38e-01 0.11 0.142 0.865 B_Memory LOneK1K
ENSG00000116791 CRYZ -41819 sc-eQTL 9.04e-01 -0.0132 0.109 0.865 B_Naive LOneK1K
ENSG00000162623 TYW3 -41563 sc-eQTL 2.92e-03 -0.422 0.14 0.865 B_Naive LOneK1K
ENSG00000254685 FPGT 493377 sc-eQTL 9.06e-01 -0.0163 0.138 0.865 B_Naive LOneK1K
ENSG00000116791 CRYZ -41819 sc-eQTL 8.81e-01 -0.0226 0.15 0.865 CD14_Mono LOneK1K
ENSG00000162623 TYW3 -41563 sc-eQTL 4.91e-01 -0.0941 0.136 0.865 CD14_Mono LOneK1K
ENSG00000254685 FPGT 493377 sc-eQTL 9.03e-01 -0.0151 0.124 0.865 CD14_Mono LOneK1K
ENSG00000116791 CRYZ -41819 sc-eQTL 9.58e-02 -0.243 0.145 0.869 CD16_Mono LOneK1K
ENSG00000162623 TYW3 -41563 sc-eQTL 6.48e-01 0.0678 0.148 0.869 CD16_Mono LOneK1K
ENSG00000254685 FPGT 493377 sc-eQTL 4.40e-01 -0.106 0.137 0.869 CD16_Mono LOneK1K
ENSG00000116791 CRYZ -41819 sc-eQTL 4.86e-01 -0.0773 0.111 0.871 NK_CD56dim LOneK1K
ENSG00000162623 TYW3 -41563 sc-eQTL 4.19e-01 0.106 0.13 0.871 NK_CD56dim LOneK1K
ENSG00000254685 FPGT 493377 sc-eQTL 2.70e-01 0.151 0.137 0.871 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000116791 CRYZ -41819 eQTL 8.7e-08 -0.167 0.031 0.0 0.0 0.13
ENSG00000162623 TYW3 -41563 eQTL 0.0424 -0.0413 0.0203 0.0 0.0 0.13
ENSG00000178965 ERICH3 17797 eQTL 0.0397 0.0631 0.0307 0.0 0.0 0.13

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000116791 CRYZ -41819 9.86e-06 9.73e-06 1.43e-06 6.02e-06 2.43e-06 4.65e-06 1.15e-05 1.92e-06 9.1e-06 5.06e-06 1.2e-05 5.26e-06 1.44e-05 3.91e-06 2.59e-06 6.54e-06 4.9e-06 7.78e-06 2.61e-06 2.8e-06 5.55e-06 9.07e-06 8.25e-06 3.54e-06 1.48e-05 3.77e-06 4.65e-06 3.68e-06 1.07e-05 1.14e-05 5.48e-06 9.86e-07 1.11e-06 3.55e-06 4.54e-06 2.67e-06 1.79e-06 1.95e-06 2.15e-06 1.08e-06 1.07e-06 1.25e-05 1.38e-06 2.2e-07 7.6e-07 1.62e-06 1.39e-06 8.09e-07 4.86e-07