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Genes within 1Mb (chr1:74665997:T:C):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -67411 sc-eQTL 3.17e-02 0.132 0.0611 0.299 B L1
ENSG00000162623 TYW3 -67155 sc-eQTL 6.86e-01 0.0352 0.0869 0.299 B L1
ENSG00000254685 FPGT 467785 sc-eQTL 1.55e-01 0.126 0.0884 0.299 B L1
ENSG00000116791 CRYZ -67411 sc-eQTL 1.80e-01 0.0879 0.0654 0.299 CD4T L1
ENSG00000162623 TYW3 -67155 sc-eQTL 1.49e-01 0.113 0.0779 0.299 CD4T L1
ENSG00000254685 FPGT 467785 sc-eQTL 6.66e-01 -0.0336 0.0779 0.299 CD4T L1
ENSG00000116791 CRYZ -67411 sc-eQTL 2.59e-03 0.202 0.0661 0.299 CD8T L1
ENSG00000162623 TYW3 -67155 sc-eQTL 9.97e-01 0.000301 0.083 0.299 CD8T L1
ENSG00000254685 FPGT 467785 sc-eQTL 3.31e-01 0.0888 0.0912 0.299 CD8T L1
ENSG00000116791 CRYZ -67411 sc-eQTL 8.08e-01 -0.0233 0.096 0.302 DC L1
ENSG00000162623 TYW3 -67155 sc-eQTL 8.56e-01 -0.0173 0.0949 0.302 DC L1
ENSG00000254685 FPGT 467785 sc-eQTL 1.24e-01 0.15 0.0968 0.302 DC L1
ENSG00000116791 CRYZ -67411 sc-eQTL 3.77e-02 0.21 0.1 0.299 Mono L1
ENSG00000162623 TYW3 -67155 sc-eQTL 4.36e-02 0.185 0.0909 0.299 Mono L1
ENSG00000254685 FPGT 467785 sc-eQTL 1.73e-01 0.106 0.0777 0.299 Mono L1
ENSG00000116791 CRYZ -67411 sc-eQTL 4.43e-01 0.0543 0.0706 0.3 NK L1
ENSG00000162623 TYW3 -67155 sc-eQTL 7.95e-01 -0.022 0.0843 0.3 NK L1
ENSG00000254685 FPGT 467785 sc-eQTL 7.35e-01 0.0288 0.085 0.3 NK L1
ENSG00000116791 CRYZ -67411 sc-eQTL 3.47e-02 0.179 0.0842 0.299 Other_T L1
ENSG00000162623 TYW3 -67155 sc-eQTL 4.76e-01 0.0541 0.0757 0.299 Other_T L1
ENSG00000254685 FPGT 467785 sc-eQTL 6.02e-01 -0.0485 0.0927 0.299 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -67411 sc-eQTL 4.90e-01 0.0708 0.102 0.309 B_Activated L2
ENSG00000162623 TYW3 -67155 sc-eQTL 4.42e-01 -0.0834 0.108 0.309 B_Activated L2
ENSG00000254685 FPGT 467785 sc-eQTL 3.05e-01 -0.1 0.0976 0.309 B_Activated L2
ENSG00000116791 CRYZ -67411 sc-eQTL 4.95e-01 0.052 0.0761 0.3 B_Intermediate L2
ENSG00000162623 TYW3 -67155 sc-eQTL 5.74e-01 -0.0566 0.101 0.3 B_Intermediate L2
ENSG00000254685 FPGT 467785 sc-eQTL 8.87e-02 0.159 0.0932 0.3 B_Intermediate L2
ENSG00000116791 CRYZ -67411 sc-eQTL 7.22e-01 0.0288 0.081 0.3 B_Memory L2
ENSG00000162623 TYW3 -67155 sc-eQTL 1.53e-01 0.137 0.0955 0.3 B_Memory L2
ENSG00000254685 FPGT 467785 sc-eQTL 3.94e-01 0.0828 0.0969 0.3 B_Memory L2
ENSG00000116791 CRYZ -67411 sc-eQTL 7.31e-02 0.148 0.0824 0.299 B_Naive1 L2
ENSG00000162623 TYW3 -67155 sc-eQTL 6.02e-01 -0.0531 0.102 0.299 B_Naive1 L2
ENSG00000254685 FPGT 467785 sc-eQTL 7.03e-01 0.0362 0.0949 0.299 B_Naive1 L2
ENSG00000116791 CRYZ -67411 sc-eQTL 7.28e-02 0.149 0.0824 0.3 B_Naive2 L2
ENSG00000162623 TYW3 -67155 sc-eQTL 7.26e-01 0.0348 0.0992 0.3 B_Naive2 L2
ENSG00000254685 FPGT 467785 sc-eQTL 9.15e-01 0.0102 0.0955 0.3 B_Naive2 L2
ENSG00000116791 CRYZ -67411 sc-eQTL 2.28e-01 0.117 0.0964 0.307 CD4_CTL L2
ENSG00000162623 TYW3 -67155 sc-eQTL 4.14e-01 -0.0835 0.102 0.307 CD4_CTL L2
ENSG00000254685 FPGT 467785 sc-eQTL 6.69e-02 0.162 0.0879 0.307 CD4_CTL L2
ENSG00000116791 CRYZ -67411 sc-eQTL 1.76e-01 0.101 0.074 0.299 CD4_Naive L2
ENSG00000162623 TYW3 -67155 sc-eQTL 1.19e-01 0.139 0.0888 0.299 CD4_Naive L2
ENSG00000254685 FPGT 467785 sc-eQTL 3.87e-01 0.0751 0.0867 0.299 CD4_Naive L2
ENSG00000116791 CRYZ -67411 sc-eQTL 1.67e-01 0.101 0.073 0.299 CD4_TCM L2
ENSG00000162623 TYW3 -67155 sc-eQTL 3.94e-02 0.19 0.0917 0.299 CD4_TCM L2
ENSG00000254685 FPGT 467785 sc-eQTL 2.70e-01 -0.103 0.0936 0.299 CD4_TCM L2
ENSG00000116791 CRYZ -67411 sc-eQTL 6.14e-01 0.0433 0.0859 0.299 CD4_TEM L2
ENSG00000162623 TYW3 -67155 sc-eQTL 7.92e-01 0.0261 0.0989 0.299 CD4_TEM L2
ENSG00000254685 FPGT 467785 sc-eQTL 4.61e-01 -0.069 0.0934 0.299 CD4_TEM L2
ENSG00000116791 CRYZ -67411 sc-eQTL 3.60e-03 0.23 0.0781 0.299 CD8_CTL L2
ENSG00000162623 TYW3 -67155 sc-eQTL 7.17e-01 -0.0354 0.0974 0.299 CD8_CTL L2
ENSG00000254685 FPGT 467785 sc-eQTL 6.05e-01 -0.0478 0.0923 0.299 CD8_CTL L2
ENSG00000116791 CRYZ -67411 sc-eQTL 8.47e-02 0.136 0.0783 0.299 CD8_Naive L2
ENSG00000162623 TYW3 -67155 sc-eQTL 4.20e-01 0.0716 0.0885 0.299 CD8_Naive L2
ENSG00000254685 FPGT 467785 sc-eQTL 1.82e-01 0.124 0.0927 0.299 CD8_Naive L2
ENSG00000116791 CRYZ -67411 sc-eQTL 6.52e-01 0.0398 0.0882 0.308 CD8_TCM L2
ENSG00000162623 TYW3 -67155 sc-eQTL 3.28e-01 -0.0998 0.102 0.308 CD8_TCM L2
ENSG00000254685 FPGT 467785 sc-eQTL 9.22e-01 0.00901 0.0918 0.308 CD8_TCM L2
ENSG00000116791 CRYZ -67411 sc-eQTL 9.84e-01 0.00193 0.0962 0.304 CD8_TEM L2
ENSG00000162623 TYW3 -67155 sc-eQTL 3.64e-01 0.0893 0.0982 0.304 CD8_TEM L2
ENSG00000254685 FPGT 467785 sc-eQTL 5.68e-01 0.0509 0.089 0.304 CD8_TEM L2
ENSG00000116791 CRYZ -67411 sc-eQTL 2.69e-01 0.0961 0.0866 0.303 MAIT L2
ENSG00000162623 TYW3 -67155 sc-eQTL 1.53e-01 0.147 0.103 0.303 MAIT L2
ENSG00000254685 FPGT 467785 sc-eQTL 5.68e-01 0.0506 0.0885 0.303 MAIT L2
ENSG00000116791 CRYZ -67411 sc-eQTL 5.01e-02 0.187 0.0947 0.298 NK_CD56bright L2
ENSG00000162623 TYW3 -67155 sc-eQTL 4.14e-01 0.084 0.103 0.298 NK_CD56bright L2
ENSG00000254685 FPGT 467785 sc-eQTL 3.29e-01 -0.0879 0.0898 0.298 NK_CD56bright L2
ENSG00000116791 CRYZ -67411 sc-eQTL 7.48e-01 -0.026 0.081 0.302 NK_CD56dim L2
ENSG00000162623 TYW3 -67155 sc-eQTL 5.26e-01 -0.0581 0.0914 0.302 NK_CD56dim L2
ENSG00000254685 FPGT 467785 sc-eQTL 8.08e-01 -0.0229 0.0942 0.302 NK_CD56dim L2
ENSG00000116791 CRYZ -67411 sc-eQTL 3.07e-02 0.217 0.0997 0.297 NK_HLA L2
ENSG00000162623 TYW3 -67155 sc-eQTL 9.56e-01 0.0058 0.104 0.297 NK_HLA L2
ENSG00000254685 FPGT 467785 sc-eQTL 4.55e-01 -0.0755 0.101 0.297 NK_HLA L2
ENSG00000116791 CRYZ -67411 sc-eQTL 6.72e-01 0.0357 0.0841 0.302 NK_cytokine L2
ENSG00000162623 TYW3 -67155 sc-eQTL 3.25e-01 -0.0903 0.0915 0.302 NK_cytokine L2
ENSG00000254685 FPGT 467785 sc-eQTL 5.33e-02 0.174 0.0893 0.302 NK_cytokine L2
ENSG00000116791 CRYZ -67411 sc-eQTL 1.80e-02 0.292 0.122 0.281 PB L2
ENSG00000162623 TYW3 -67155 sc-eQTL 5.15e-01 0.0784 0.12 0.281 PB L2
ENSG00000254685 FPGT 467785 sc-eQTL 6.89e-01 0.0478 0.119 0.281 PB L2
ENSG00000116791 CRYZ -67411 sc-eQTL 1.70e-01 0.14 0.101 0.3 Pro_T L2
ENSG00000162623 TYW3 -67155 sc-eQTL 9.70e-01 0.00302 0.0798 0.3 Pro_T L2
ENSG00000254685 FPGT 467785 sc-eQTL 7.27e-01 -0.0319 0.0911 0.3 Pro_T L2
ENSG00000116791 CRYZ -67411 sc-eQTL 1.15e-02 0.232 0.0911 0.299 Treg L2
ENSG00000162623 TYW3 -67155 sc-eQTL 3.73e-01 -0.0837 0.0938 0.299 Treg L2
ENSG00000254685 FPGT 467785 sc-eQTL 1.21e-01 -0.142 0.0914 0.299 Treg L2
ENSG00000116791 CRYZ -67411 sc-eQTL 3.82e-01 0.0888 0.101 0.302 cDC L2
ENSG00000162623 TYW3 -67155 sc-eQTL 5.90e-01 0.055 0.102 0.302 cDC L2
ENSG00000254685 FPGT 467785 sc-eQTL 7.71e-02 0.184 0.104 0.302 cDC L2
ENSG00000116791 CRYZ -67411 sc-eQTL 9.46e-03 0.258 0.0985 0.299 cMono_IL1B L2
ENSG00000162623 TYW3 -67155 sc-eQTL 4.46e-02 0.191 0.0945 0.299 cMono_IL1B L2
ENSG00000254685 FPGT 467785 sc-eQTL 1.87e-01 0.119 0.09 0.299 cMono_IL1B L2
ENSG00000116791 CRYZ -67411 sc-eQTL 4.28e-01 0.0781 0.0984 0.299 cMono_S100A L2
ENSG00000162623 TYW3 -67155 sc-eQTL 5.80e-01 0.0556 0.1 0.299 cMono_S100A L2
ENSG00000254685 FPGT 467785 sc-eQTL 2.17e-01 0.111 0.0895 0.299 cMono_S100A L2
ENSG00000116791 CRYZ -67411 sc-eQTL 4.57e-01 -0.0779 0.105 0.318 gdT L2
ENSG00000162623 TYW3 -67155 sc-eQTL 2.99e-01 -0.117 0.112 0.318 gdT L2
ENSG00000254685 FPGT 467785 sc-eQTL 8.75e-01 0.0167 0.106 0.318 gdT L2
ENSG00000116791 CRYZ -67411 sc-eQTL 3.48e-01 0.0905 0.0963 0.3 intMono L2
ENSG00000162623 TYW3 -67155 sc-eQTL 2.26e-01 0.127 0.105 0.3 intMono L2
ENSG00000254685 FPGT 467785 sc-eQTL 6.71e-01 -0.0415 0.0975 0.3 intMono L2
ENSG00000116791 CRYZ -67411 sc-eQTL 3.32e-02 0.206 0.096 0.296 ncMono L2
ENSG00000162623 TYW3 -67155 sc-eQTL 2.25e-01 0.131 0.108 0.296 ncMono L2
ENSG00000254685 FPGT 467785 sc-eQTL 6.40e-01 0.0436 0.093 0.296 ncMono L2
ENSG00000116791 CRYZ -67411 sc-eQTL 7.27e-01 -0.0378 0.108 0.314 pDC L2
ENSG00000162623 TYW3 -67155 sc-eQTL 1.35e-01 0.159 0.106 0.314 pDC L2
ENSG00000254685 FPGT 467785 sc-eQTL 9.27e-01 0.00908 0.0989 0.314 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -67411 sc-eQTL 2.29e-01 0.0823 0.0682 0.299 B_Memory LOneK1K
ENSG00000162623 TYW3 -67155 sc-eQTL 7.99e-01 0.0251 0.0987 0.299 B_Memory LOneK1K
ENSG00000254685 FPGT 467785 sc-eQTL 1.36e-01 0.143 0.0956 0.299 B_Memory LOneK1K
ENSG00000116791 CRYZ -67411 sc-eQTL 4.88e-02 0.147 0.0744 0.299 B_Naive LOneK1K
ENSG00000162623 TYW3 -67155 sc-eQTL 8.31e-01 0.021 0.0985 0.299 B_Naive LOneK1K
ENSG00000254685 FPGT 467785 sc-eQTL 9.22e-01 -0.00926 0.095 0.299 B_Naive LOneK1K
ENSG00000116791 CRYZ -67411 sc-eQTL 5.22e-02 0.197 0.101 0.299 CD14_Mono LOneK1K
ENSG00000162623 TYW3 -67155 sc-eQTL 4.37e-02 0.186 0.0917 0.299 CD14_Mono LOneK1K
ENSG00000254685 FPGT 467785 sc-eQTL 9.99e-02 0.138 0.0835 0.299 CD14_Mono LOneK1K
ENSG00000116791 CRYZ -67411 sc-eQTL 1.55e-01 0.141 0.0985 0.3 CD16_Mono LOneK1K
ENSG00000162623 TYW3 -67155 sc-eQTL 4.65e-02 0.2 0.0997 0.3 CD16_Mono LOneK1K
ENSG00000254685 FPGT 467785 sc-eQTL 8.33e-01 -0.0196 0.0928 0.3 CD16_Mono LOneK1K
ENSG00000116791 CRYZ -67411 sc-eQTL 6.88e-01 0.0294 0.0729 0.302 NK_CD56dim LOneK1K
ENSG00000162623 TYW3 -67155 sc-eQTL 4.31e-01 -0.0677 0.0857 0.302 NK_CD56dim LOneK1K
ENSG00000254685 FPGT 467785 sc-eQTL 6.97e-01 0.0351 0.0901 0.302 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000116791 CRYZ -67411 eQTL 1.07e-06 0.119 0.0242 0.0 0.0 0.293
ENSG00000162623 TYW3 -67155 eQTL 0.000245 0.0579 0.0157 0.0 0.0 0.293

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000116791 CRYZ -67411 6.46e-06 7.73e-06 1.34e-06 3.85e-06 2.25e-06 2.81e-06 9.53e-06 1.69e-06 6.04e-06 4.1e-06 8.8e-06 3.89e-06 1.13e-05 3.14e-06 1.69e-06 5.69e-06 3.71e-06 4.76e-06 2.64e-06 2.63e-06 4.38e-06 7.66e-06 6.46e-06 3.21e-06 1.03e-05 3.11e-06 4.07e-06 2.61e-06 7.52e-06 7.77e-06 3.88e-06 9.05e-07 1.29e-06 2.99e-06 2.8e-06 2.21e-06 1.73e-06 1.74e-06 1.63e-06 1e-06 1.01e-06 8.16e-06 8.97e-07 2.03e-07 8.18e-07 1.32e-06 1.23e-06 7.76e-07 4.14e-07
ENSG00000162623 TYW3 -67155 6.54e-06 7.75e-06 1.32e-06 3.85e-06 2.25e-06 2.96e-06 9.53e-06 1.69e-06 6.04e-06 4.12e-06 8.89e-06 3.9e-06 1.13e-05 3.14e-06 1.69e-06 5.77e-06 3.71e-06 4.84e-06 2.66e-06 2.59e-06 4.39e-06 7.66e-06 6.55e-06 3.21e-06 1.03e-05 3.11e-06 4.15e-06 2.61e-06 7.52e-06 7.78e-06 3.88e-06 8.89e-07 1.27e-06 3e-06 2.8e-06 2.21e-06 1.73e-06 1.75e-06 1.68e-06 1e-06 1.01e-06 8.07e-06 9.29e-07 2.03e-07 8.18e-07 1.32e-06 1.23e-06 8.03e-07 4.27e-07