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Genes within 1Mb (chr1:74204227:T:C):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -529181 sc-eQTL 6.74e-01 -0.0246 0.0585 0.682 B L1
ENSG00000162623 TYW3 -528925 sc-eQTL 2.92e-01 -0.0867 0.0821 0.682 B L1
ENSG00000254685 FPGT 6015 sc-eQTL 1.78e-05 -0.354 0.0805 0.682 B L1
ENSG00000116791 CRYZ -529181 sc-eQTL 5.60e-01 -0.0352 0.0602 0.682 CD4T L1
ENSG00000162623 TYW3 -528925 sc-eQTL 2.91e-03 -0.212 0.0704 0.682 CD4T L1
ENSG00000254685 FPGT 6015 sc-eQTL 3.12e-08 -0.382 0.0665 0.682 CD4T L1
ENSG00000116791 CRYZ -529181 sc-eQTL 8.50e-01 -0.0119 0.0628 0.682 CD8T L1
ENSG00000162623 TYW3 -528925 sc-eQTL 3.95e-01 -0.0656 0.077 0.682 CD8T L1
ENSG00000254685 FPGT 6015 sc-eQTL 4.52e-06 -0.38 0.0808 0.682 CD8T L1
ENSG00000116791 CRYZ -529181 sc-eQTL 7.64e-01 0.0256 0.0854 0.682 DC L1
ENSG00000162623 TYW3 -528925 sc-eQTL 4.48e-01 0.0642 0.0844 0.682 DC L1
ENSG00000254685 FPGT 6015 sc-eQTL 1.91e-01 -0.113 0.0863 0.682 DC L1
ENSG00000116791 CRYZ -529181 sc-eQTL 7.83e-01 0.0257 0.0931 0.682 Mono L1
ENSG00000162623 TYW3 -528925 sc-eQTL 1.54e-01 -0.12 0.0839 0.682 Mono L1
ENSG00000254685 FPGT 6015 sc-eQTL 4.08e-05 -0.289 0.0688 0.682 Mono L1
ENSG00000116791 CRYZ -529181 sc-eQTL 6.91e-01 0.0264 0.0662 0.682 NK L1
ENSG00000162623 TYW3 -528925 sc-eQTL 3.16e-01 0.0791 0.0788 0.682 NK L1
ENSG00000254685 FPGT 6015 sc-eQTL 1.21e-07 -0.408 0.0745 0.682 NK L1
ENSG00000116791 CRYZ -529181 sc-eQTL 4.27e-01 -0.0639 0.0804 0.682 Other_T L1
ENSG00000162623 TYW3 -528925 sc-eQTL 2.93e-01 -0.0754 0.0715 0.682 Other_T L1
ENSG00000254685 FPGT 6015 sc-eQTL 2.98e-01 -0.0912 0.0875 0.682 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -529181 sc-eQTL 1.67e-01 -0.133 0.0956 0.694 B_Activated L2
ENSG00000162623 TYW3 -528925 sc-eQTL 8.77e-01 -0.0157 0.102 0.694 B_Activated L2
ENSG00000254685 FPGT 6015 sc-eQTL 1.83e-04 -0.337 0.0882 0.694 B_Activated L2
ENSG00000116791 CRYZ -529181 sc-eQTL 3.69e-01 0.0648 0.072 0.68 B_Intermediate L2
ENSG00000162623 TYW3 -528925 sc-eQTL 7.13e-01 -0.0351 0.0954 0.68 B_Intermediate L2
ENSG00000254685 FPGT 6015 sc-eQTL 2.43e-02 -0.199 0.0879 0.68 B_Intermediate L2
ENSG00000116791 CRYZ -529181 sc-eQTL 9.15e-01 -0.00818 0.0767 0.679 B_Memory L2
ENSG00000162623 TYW3 -528925 sc-eQTL 7.60e-01 0.0278 0.0908 0.679 B_Memory L2
ENSG00000254685 FPGT 6015 sc-eQTL 1.90e-01 -0.12 0.0915 0.679 B_Memory L2
ENSG00000116791 CRYZ -529181 sc-eQTL 7.17e-01 -0.0281 0.0774 0.682 B_Naive1 L2
ENSG00000162623 TYW3 -528925 sc-eQTL 8.45e-01 0.0186 0.0948 0.682 B_Naive1 L2
ENSG00000254685 FPGT 6015 sc-eQTL 2.61e-02 -0.196 0.0874 0.682 B_Naive1 L2
ENSG00000116791 CRYZ -529181 sc-eQTL 5.67e-01 -0.0449 0.0783 0.68 B_Naive2 L2
ENSG00000162623 TYW3 -528925 sc-eQTL 4.08e-01 -0.0775 0.0935 0.68 B_Naive2 L2
ENSG00000254685 FPGT 6015 sc-eQTL 2.91e-02 -0.196 0.0891 0.68 B_Naive2 L2
ENSG00000116791 CRYZ -529181 sc-eQTL 8.64e-01 0.0155 0.0903 0.684 CD4_CTL L2
ENSG00000162623 TYW3 -528925 sc-eQTL 7.58e-01 0.0295 0.0953 0.684 CD4_CTL L2
ENSG00000254685 FPGT 6015 sc-eQTL 1.59e-01 -0.116 0.0823 0.684 CD4_CTL L2
ENSG00000116791 CRYZ -529181 sc-eQTL 5.06e-01 -0.0446 0.067 0.682 CD4_Naive L2
ENSG00000162623 TYW3 -528925 sc-eQTL 8.91e-03 -0.21 0.0794 0.682 CD4_Naive L2
ENSG00000254685 FPGT 6015 sc-eQTL 3.20e-05 -0.32 0.0753 0.682 CD4_Naive L2
ENSG00000116791 CRYZ -529181 sc-eQTL 8.56e-01 -0.0124 0.0682 0.682 CD4_TCM L2
ENSG00000162623 TYW3 -528925 sc-eQTL 8.01e-02 -0.15 0.0855 0.682 CD4_TCM L2
ENSG00000254685 FPGT 6015 sc-eQTL 6.02e-04 -0.296 0.0849 0.682 CD4_TCM L2
ENSG00000116791 CRYZ -529181 sc-eQTL 5.45e-01 -0.049 0.0807 0.682 CD4_TEM L2
ENSG00000162623 TYW3 -528925 sc-eQTL 7.95e-01 0.0241 0.093 0.682 CD4_TEM L2
ENSG00000254685 FPGT 6015 sc-eQTL 3.24e-01 -0.0867 0.0877 0.682 CD4_TEM L2
ENSG00000116791 CRYZ -529181 sc-eQTL 7.99e-01 -0.0192 0.075 0.682 CD8_CTL L2
ENSG00000162623 TYW3 -528925 sc-eQTL 8.88e-01 0.013 0.0918 0.682 CD8_CTL L2
ENSG00000254685 FPGT 6015 sc-eQTL 3.60e-04 -0.306 0.0844 0.682 CD8_CTL L2
ENSG00000116791 CRYZ -529181 sc-eQTL 2.25e-01 -0.0888 0.073 0.682 CD8_Naive L2
ENSG00000162623 TYW3 -528925 sc-eQTL 4.92e-01 -0.0566 0.0823 0.682 CD8_Naive L2
ENSG00000254685 FPGT 6015 sc-eQTL 1.63e-03 -0.27 0.0845 0.682 CD8_Naive L2
ENSG00000116791 CRYZ -529181 sc-eQTL 9.41e-01 -0.00617 0.0828 0.692 CD8_TCM L2
ENSG00000162623 TYW3 -528925 sc-eQTL 8.68e-01 -0.0159 0.0956 0.692 CD8_TCM L2
ENSG00000254685 FPGT 6015 sc-eQTL 2.50e-01 -0.099 0.0859 0.692 CD8_TCM L2
ENSG00000116791 CRYZ -529181 sc-eQTL 7.76e-02 0.158 0.0889 0.685 CD8_TEM L2
ENSG00000162623 TYW3 -528925 sc-eQTL 2.58e-01 0.104 0.0914 0.685 CD8_TEM L2
ENSG00000254685 FPGT 6015 sc-eQTL 2.00e-01 -0.106 0.0826 0.685 CD8_TEM L2
ENSG00000116791 CRYZ -529181 sc-eQTL 9.23e-02 -0.136 0.0804 0.686 MAIT L2
ENSG00000162623 TYW3 -528925 sc-eQTL 8.02e-01 0.0241 0.0961 0.686 MAIT L2
ENSG00000254685 FPGT 6015 sc-eQTL 5.95e-01 -0.044 0.0826 0.686 MAIT L2
ENSG00000116791 CRYZ -529181 sc-eQTL 7.48e-01 0.0291 0.0902 0.687 NK_CD56bright L2
ENSG00000162623 TYW3 -528925 sc-eQTL 6.46e-01 0.0446 0.097 0.687 NK_CD56bright L2
ENSG00000254685 FPGT 6015 sc-eQTL 3.65e-01 -0.0769 0.0848 0.687 NK_CD56bright L2
ENSG00000116791 CRYZ -529181 sc-eQTL 1.95e-01 -0.0976 0.0751 0.681 NK_CD56dim L2
ENSG00000162623 TYW3 -528925 sc-eQTL 8.82e-01 0.0127 0.0852 0.681 NK_CD56dim L2
ENSG00000254685 FPGT 6015 sc-eQTL 3.24e-05 -0.357 0.0841 0.681 NK_CD56dim L2
ENSG00000116791 CRYZ -529181 sc-eQTL 7.88e-01 0.0247 0.0916 0.678 NK_HLA L2
ENSG00000162623 TYW3 -528925 sc-eQTL 1.12e-01 0.15 0.0939 0.678 NK_HLA L2
ENSG00000254685 FPGT 6015 sc-eQTL 2.76e-01 -0.0998 0.0914 0.678 NK_HLA L2
ENSG00000116791 CRYZ -529181 sc-eQTL 4.50e-02 0.158 0.0782 0.681 NK_cytokine L2
ENSG00000162623 TYW3 -528925 sc-eQTL 2.81e-01 0.0928 0.0858 0.681 NK_cytokine L2
ENSG00000254685 FPGT 6015 sc-eQTL 2.14e-02 -0.194 0.0835 0.681 NK_cytokine L2
ENSG00000116791 CRYZ -529181 sc-eQTL 3.43e-01 0.114 0.12 0.685 PB L2
ENSG00000162623 TYW3 -528925 sc-eQTL 2.66e-01 0.128 0.115 0.685 PB L2
ENSG00000254685 FPGT 6015 sc-eQTL 3.25e-01 0.113 0.114 0.685 PB L2
ENSG00000116791 CRYZ -529181 sc-eQTL 2.70e-01 -0.102 0.0921 0.685 Pro_T L2
ENSG00000162623 TYW3 -528925 sc-eQTL 4.78e-01 0.0514 0.0723 0.685 Pro_T L2
ENSG00000254685 FPGT 6015 sc-eQTL 4.13e-01 -0.0678 0.0826 0.685 Pro_T L2
ENSG00000116791 CRYZ -529181 sc-eQTL 8.77e-01 0.0134 0.0867 0.682 Treg L2
ENSG00000162623 TYW3 -528925 sc-eQTL 1.69e-01 -0.121 0.0877 0.682 Treg L2
ENSG00000254685 FPGT 6015 sc-eQTL 5.10e-02 -0.168 0.0854 0.682 Treg L2
ENSG00000116791 CRYZ -529181 sc-eQTL 8.19e-01 0.02 0.0874 0.673 cDC L2
ENSG00000162623 TYW3 -528925 sc-eQTL 8.18e-01 0.0202 0.0877 0.673 cDC L2
ENSG00000254685 FPGT 6015 sc-eQTL 9.46e-03 -0.232 0.0884 0.673 cDC L2
ENSG00000116791 CRYZ -529181 sc-eQTL 5.03e-01 0.0614 0.0916 0.682 cMono_IL1B L2
ENSG00000162623 TYW3 -528925 sc-eQTL 5.12e-02 -0.17 0.0866 0.682 cMono_IL1B L2
ENSG00000254685 FPGT 6015 sc-eQTL 6.37e-04 -0.279 0.0805 0.682 cMono_IL1B L2
ENSG00000116791 CRYZ -529181 sc-eQTL 6.13e-01 -0.0456 0.09 0.682 cMono_S100A L2
ENSG00000162623 TYW3 -528925 sc-eQTL 9.53e-01 0.00545 0.0918 0.682 cMono_S100A L2
ENSG00000254685 FPGT 6015 sc-eQTL 1.08e-03 -0.265 0.0801 0.682 cMono_S100A L2
ENSG00000116791 CRYZ -529181 sc-eQTL 8.25e-01 -0.0212 0.0958 0.694 gdT L2
ENSG00000162623 TYW3 -528925 sc-eQTL 2.31e-01 -0.123 0.102 0.694 gdT L2
ENSG00000254685 FPGT 6015 sc-eQTL 4.30e-02 -0.196 0.0957 0.694 gdT L2
ENSG00000116791 CRYZ -529181 sc-eQTL 7.12e-01 0.032 0.0865 0.684 intMono L2
ENSG00000162623 TYW3 -528925 sc-eQTL 1.18e-02 -0.235 0.0926 0.684 intMono L2
ENSG00000254685 FPGT 6015 sc-eQTL 4.23e-01 -0.0701 0.0873 0.684 intMono L2
ENSG00000116791 CRYZ -529181 sc-eQTL 3.97e-01 -0.0723 0.0851 0.681 ncMono L2
ENSG00000162623 TYW3 -528925 sc-eQTL 3.23e-01 -0.0941 0.0949 0.681 ncMono L2
ENSG00000254685 FPGT 6015 sc-eQTL 2.39e-01 -0.0962 0.0815 0.681 ncMono L2
ENSG00000116791 CRYZ -529181 sc-eQTL 2.60e-01 0.109 0.0968 0.678 pDC L2
ENSG00000162623 TYW3 -528925 sc-eQTL 2.18e-01 0.118 0.0953 0.678 pDC L2
ENSG00000254685 FPGT 6015 sc-eQTL 3.72e-01 0.0795 0.0888 0.678 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -529181 sc-eQTL 7.61e-01 0.0197 0.0645 0.682 B_Memory LOneK1K
ENSG00000162623 TYW3 -528925 sc-eQTL 7.76e-01 -0.0265 0.093 0.682 B_Memory LOneK1K
ENSG00000254685 FPGT 6015 sc-eQTL 2.15e-04 -0.33 0.0877 0.682 B_Memory LOneK1K
ENSG00000116791 CRYZ -529181 sc-eQTL 5.05e-01 -0.0465 0.0697 0.682 B_Naive LOneK1K
ENSG00000162623 TYW3 -528925 sc-eQTL 7.53e-01 -0.0289 0.0914 0.682 B_Naive LOneK1K
ENSG00000254685 FPGT 6015 sc-eQTL 3.81e-03 -0.253 0.0865 0.682 B_Naive LOneK1K
ENSG00000116791 CRYZ -529181 sc-eQTL 6.33e-01 0.0443 0.0928 0.682 CD14_Mono LOneK1K
ENSG00000162623 TYW3 -528925 sc-eQTL 2.14e-01 -0.105 0.0841 0.682 CD14_Mono LOneK1K
ENSG00000254685 FPGT 6015 sc-eQTL 3.19e-05 -0.313 0.0736 0.682 CD14_Mono LOneK1K
ENSG00000116791 CRYZ -529181 sc-eQTL 8.21e-01 -0.0202 0.089 0.681 CD16_Mono LOneK1K
ENSG00000162623 TYW3 -528925 sc-eQTL 7.09e-02 -0.163 0.0898 0.681 CD16_Mono LOneK1K
ENSG00000254685 FPGT 6015 sc-eQTL 6.53e-02 -0.153 0.0828 0.681 CD16_Mono LOneK1K
ENSG00000116791 CRYZ -529181 sc-eQTL 6.25e-01 0.0336 0.0685 0.681 NK_CD56dim LOneK1K
ENSG00000162623 TYW3 -528925 sc-eQTL 4.30e-01 0.0637 0.0805 0.681 NK_CD56dim LOneK1K
ENSG00000254685 FPGT 6015 sc-eQTL 5.13e-08 -0.446 0.0789 0.681 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000162620 LRRIQ3 6040 eQTL 2.23e-109 -0.749 0.0294 0.0171 0.0362 0.32
ENSG00000254685 FPGT 6015 eQTL 1.02e-84 -0.337 0.0156 0.0223 0.0357 0.32

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000162620 LRRIQ3 6040 3.98e-05 3.46e-05 6.41e-06 1.61e-05 6.22e-06 1.52e-05 4.75e-05 4.96e-06 3.38e-05 1.63e-05 4.09e-05 1.87e-05 5.15e-05 1.52e-05 7.4e-06 2.07e-05 1.89e-05 2.74e-05 8.23e-06 7.09e-06 1.69e-05 3.64e-05 3.45e-05 9.6e-06 4.72e-05 8.39e-06 1.53e-05 1.39e-05 3.47e-05 2.71e-05 2.17e-05 1.63e-06 2.8e-06 7.41e-06 1.23e-05 5.99e-06 3.22e-06 3.17e-06 5e-06 3.4e-06 1.74e-06 4.06e-05 3.99e-06 3.62e-07 2.67e-06 4.28e-06 4.14e-06 1.69e-06 1.5e-06
ENSG00000254685 FPGT 6015 3.98e-05 3.46e-05 6.41e-06 1.61e-05 6.22e-06 1.52e-05 4.75e-05 4.96e-06 3.38e-05 1.64e-05 4.09e-05 1.87e-05 5.15e-05 1.52e-05 7.4e-06 2.07e-05 1.89e-05 2.74e-05 8.23e-06 7.09e-06 1.69e-05 3.64e-05 3.45e-05 9.6e-06 4.72e-05 8.39e-06 1.53e-05 1.39e-05 3.47e-05 2.71e-05 2.17e-05 1.63e-06 2.8e-06 7.41e-06 1.23e-05 5.98e-06 3.22e-06 3.17e-06 5e-06 3.4e-06 1.74e-06 4.06e-05 3.99e-06 3.62e-07 2.67e-06 4.28e-06 4.23e-06 1.69e-06 1.5e-06