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Genes within 1Mb (chr1:74200590:C:T):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -532818 sc-eQTL 7.94e-01 -0.0152 0.0583 0.684 B L1
ENSG00000162623 TYW3 -532562 sc-eQTL 3.58e-01 -0.0753 0.0818 0.684 B L1
ENSG00000254685 FPGT 2378 sc-eQTL 5.51e-06 -0.372 0.0798 0.684 B L1
ENSG00000116791 CRYZ -532818 sc-eQTL 5.74e-01 -0.0339 0.0601 0.684 CD4T L1
ENSG00000162623 TYW3 -532562 sc-eQTL 2.76e-03 -0.213 0.0702 0.684 CD4T L1
ENSG00000254685 FPGT 2378 sc-eQTL 1.45e-08 -0.39 0.0661 0.684 CD4T L1
ENSG00000116791 CRYZ -532818 sc-eQTL 9.55e-01 -0.00357 0.0627 0.684 CD8T L1
ENSG00000162623 TYW3 -532562 sc-eQTL 3.94e-01 -0.0657 0.0769 0.684 CD8T L1
ENSG00000254685 FPGT 2378 sc-eQTL 5.74e-06 -0.376 0.0808 0.684 CD8T L1
ENSG00000116791 CRYZ -532818 sc-eQTL 7.56e-01 0.0266 0.0854 0.685 DC L1
ENSG00000162623 TYW3 -532562 sc-eQTL 5.05e-01 0.0563 0.0844 0.685 DC L1
ENSG00000254685 FPGT 2378 sc-eQTL 1.64e-01 -0.121 0.0862 0.685 DC L1
ENSG00000116791 CRYZ -532818 sc-eQTL 7.29e-01 0.0323 0.0931 0.684 Mono L1
ENSG00000162623 TYW3 -532562 sc-eQTL 1.80e-01 -0.113 0.084 0.684 Mono L1
ENSG00000254685 FPGT 2378 sc-eQTL 5.05e-05 -0.285 0.0689 0.684 Mono L1
ENSG00000116791 CRYZ -532818 sc-eQTL 7.66e-01 0.0197 0.066 0.685 NK L1
ENSG00000162623 TYW3 -532562 sc-eQTL 4.90e-01 0.0544 0.0786 0.685 NK L1
ENSG00000254685 FPGT 2378 sc-eQTL 9.69e-08 -0.41 0.0742 0.685 NK L1
ENSG00000116791 CRYZ -532818 sc-eQTL 4.35e-01 -0.0627 0.0802 0.684 Other_T L1
ENSG00000162623 TYW3 -532562 sc-eQTL 2.10e-01 -0.0897 0.0713 0.684 Other_T L1
ENSG00000254685 FPGT 2378 sc-eQTL 3.58e-01 -0.0805 0.0874 0.684 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -532818 sc-eQTL 9.92e-02 -0.158 0.0951 0.696 B_Activated L2
ENSG00000162623 TYW3 -532562 sc-eQTL 9.86e-01 -0.00177 0.101 0.696 B_Activated L2
ENSG00000254685 FPGT 2378 sc-eQTL 3.73e-04 -0.321 0.0883 0.696 B_Activated L2
ENSG00000116791 CRYZ -532818 sc-eQTL 2.89e-01 0.0764 0.0719 0.682 B_Intermediate L2
ENSG00000162623 TYW3 -532562 sc-eQTL 9.83e-01 0.00207 0.0954 0.682 B_Intermediate L2
ENSG00000254685 FPGT 2378 sc-eQTL 2.46e-02 -0.199 0.0878 0.682 B_Intermediate L2
ENSG00000116791 CRYZ -532818 sc-eQTL 7.73e-01 0.0221 0.0765 0.681 B_Memory L2
ENSG00000162623 TYW3 -532562 sc-eQTL 7.17e-01 0.0329 0.0907 0.681 B_Memory L2
ENSG00000254685 FPGT 2378 sc-eQTL 9.94e-02 -0.151 0.0911 0.681 B_Memory L2
ENSG00000116791 CRYZ -532818 sc-eQTL 8.01e-01 -0.0195 0.0772 0.684 B_Naive1 L2
ENSG00000162623 TYW3 -532562 sc-eQTL 9.06e-01 0.0112 0.0946 0.684 B_Naive1 L2
ENSG00000254685 FPGT 2378 sc-eQTL 1.40e-02 -0.216 0.087 0.684 B_Naive1 L2
ENSG00000116791 CRYZ -532818 sc-eQTL 5.40e-01 -0.0478 0.0779 0.682 B_Naive2 L2
ENSG00000162623 TYW3 -532562 sc-eQTL 4.29e-01 -0.0738 0.0931 0.682 B_Naive2 L2
ENSG00000254685 FPGT 2378 sc-eQTL 1.34e-02 -0.221 0.0885 0.682 B_Naive2 L2
ENSG00000116791 CRYZ -532818 sc-eQTL 9.44e-01 0.00635 0.0901 0.686 CD4_CTL L2
ENSG00000162623 TYW3 -532562 sc-eQTL 8.39e-01 0.0194 0.0951 0.686 CD4_CTL L2
ENSG00000254685 FPGT 2378 sc-eQTL 2.07e-01 -0.104 0.0822 0.686 CD4_CTL L2
ENSG00000116791 CRYZ -532818 sc-eQTL 5.15e-01 -0.0436 0.0669 0.684 CD4_Naive L2
ENSG00000162623 TYW3 -532562 sc-eQTL 9.89e-03 -0.206 0.0793 0.684 CD4_Naive L2
ENSG00000254685 FPGT 2378 sc-eQTL 1.70e-05 -0.33 0.075 0.684 CD4_Naive L2
ENSG00000116791 CRYZ -532818 sc-eQTL 8.73e-01 -0.0109 0.0681 0.684 CD4_TCM L2
ENSG00000162623 TYW3 -532562 sc-eQTL 6.94e-02 -0.156 0.0854 0.684 CD4_TCM L2
ENSG00000254685 FPGT 2378 sc-eQTL 4.78e-04 -0.301 0.0848 0.684 CD4_TCM L2
ENSG00000116791 CRYZ -532818 sc-eQTL 4.93e-01 -0.0554 0.0807 0.684 CD4_TEM L2
ENSG00000162623 TYW3 -532562 sc-eQTL 7.86e-01 0.0252 0.093 0.684 CD4_TEM L2
ENSG00000254685 FPGT 2378 sc-eQTL 4.12e-01 -0.0722 0.0878 0.684 CD4_TEM L2
ENSG00000116791 CRYZ -532818 sc-eQTL 9.20e-01 -0.00751 0.0748 0.684 CD8_CTL L2
ENSG00000162623 TYW3 -532562 sc-eQTL 8.50e-01 0.0174 0.0916 0.684 CD8_CTL L2
ENSG00000254685 FPGT 2378 sc-eQTL 5.18e-04 -0.297 0.0843 0.684 CD8_CTL L2
ENSG00000116791 CRYZ -532818 sc-eQTL 2.69e-01 -0.0809 0.0731 0.684 CD8_Naive L2
ENSG00000162623 TYW3 -532562 sc-eQTL 5.12e-01 -0.0541 0.0823 0.684 CD8_Naive L2
ENSG00000254685 FPGT 2378 sc-eQTL 2.15e-03 -0.263 0.0846 0.684 CD8_Naive L2
ENSG00000116791 CRYZ -532818 sc-eQTL 8.59e-01 -0.0147 0.0827 0.694 CD8_TCM L2
ENSG00000162623 TYW3 -532562 sc-eQTL 7.28e-01 -0.0333 0.0956 0.694 CD8_TCM L2
ENSG00000254685 FPGT 2378 sc-eQTL 2.52e-01 -0.0985 0.0858 0.694 CD8_TCM L2
ENSG00000116791 CRYZ -532818 sc-eQTL 5.67e-02 0.17 0.0885 0.687 CD8_TEM L2
ENSG00000162623 TYW3 -532562 sc-eQTL 2.90e-01 0.0966 0.0911 0.687 CD8_TEM L2
ENSG00000254685 FPGT 2378 sc-eQTL 1.24e-01 -0.127 0.0822 0.687 CD8_TEM L2
ENSG00000116791 CRYZ -532818 sc-eQTL 8.68e-02 -0.138 0.0803 0.688 MAIT L2
ENSG00000162623 TYW3 -532562 sc-eQTL 8.27e-01 0.021 0.096 0.688 MAIT L2
ENSG00000254685 FPGT 2378 sc-eQTL 6.30e-01 -0.0397 0.0824 0.688 MAIT L2
ENSG00000116791 CRYZ -532818 sc-eQTL 6.93e-01 0.0356 0.0902 0.689 NK_CD56bright L2
ENSG00000162623 TYW3 -532562 sc-eQTL 8.00e-01 0.0246 0.097 0.689 NK_CD56bright L2
ENSG00000254685 FPGT 2378 sc-eQTL 2.46e-01 -0.0984 0.0846 0.689 NK_CD56bright L2
ENSG00000116791 CRYZ -532818 sc-eQTL 1.58e-01 -0.106 0.0749 0.683 NK_CD56dim L2
ENSG00000162623 TYW3 -532562 sc-eQTL 9.73e-01 0.00289 0.085 0.683 NK_CD56dim L2
ENSG00000254685 FPGT 2378 sc-eQTL 6.49e-05 -0.343 0.0841 0.683 NK_CD56dim L2
ENSG00000116791 CRYZ -532818 sc-eQTL 9.01e-01 0.0114 0.0915 0.68 NK_HLA L2
ENSG00000162623 TYW3 -532562 sc-eQTL 1.98e-01 0.121 0.0941 0.68 NK_HLA L2
ENSG00000254685 FPGT 2378 sc-eQTL 2.43e-01 -0.107 0.0913 0.68 NK_HLA L2
ENSG00000116791 CRYZ -532818 sc-eQTL 5.90e-02 0.148 0.0781 0.683 NK_cytokine L2
ENSG00000162623 TYW3 -532562 sc-eQTL 3.91e-01 0.0736 0.0857 0.683 NK_cytokine L2
ENSG00000254685 FPGT 2378 sc-eQTL 1.40e-02 -0.206 0.0831 0.683 NK_cytokine L2
ENSG00000116791 CRYZ -532818 sc-eQTL 3.69e-01 0.108 0.12 0.689 PB L2
ENSG00000162623 TYW3 -532562 sc-eQTL 3.09e-01 0.118 0.115 0.689 PB L2
ENSG00000254685 FPGT 2378 sc-eQTL 3.04e-01 0.118 0.114 0.689 PB L2
ENSG00000116791 CRYZ -532818 sc-eQTL 3.16e-01 -0.0927 0.0922 0.687 Pro_T L2
ENSG00000162623 TYW3 -532562 sc-eQTL 4.86e-01 0.0505 0.0723 0.687 Pro_T L2
ENSG00000254685 FPGT 2378 sc-eQTL 5.60e-01 -0.0482 0.0827 0.687 Pro_T L2
ENSG00000116791 CRYZ -532818 sc-eQTL 5.56e-01 0.0511 0.0865 0.684 Treg L2
ENSG00000162623 TYW3 -532562 sc-eQTL 1.68e-01 -0.121 0.0875 0.684 Treg L2
ENSG00000254685 FPGT 2378 sc-eQTL 5.64e-02 -0.164 0.0853 0.684 Treg L2
ENSG00000116791 CRYZ -532818 sc-eQTL 9.49e-01 0.00558 0.087 0.676 cDC L2
ENSG00000162623 TYW3 -532562 sc-eQTL 9.60e-01 0.00437 0.0873 0.676 cDC L2
ENSG00000254685 FPGT 2378 sc-eQTL 1.04e-02 -0.228 0.088 0.676 cDC L2
ENSG00000116791 CRYZ -532818 sc-eQTL 5.42e-01 0.0559 0.0915 0.684 cMono_IL1B L2
ENSG00000162623 TYW3 -532562 sc-eQTL 4.43e-02 -0.175 0.0865 0.684 cMono_IL1B L2
ENSG00000254685 FPGT 2378 sc-eQTL 8.76e-04 -0.272 0.0806 0.684 cMono_IL1B L2
ENSG00000116791 CRYZ -532818 sc-eQTL 7.73e-01 -0.0261 0.0902 0.684 cMono_S100A L2
ENSG00000162623 TYW3 -532562 sc-eQTL 8.82e-01 0.0136 0.0919 0.684 cMono_S100A L2
ENSG00000254685 FPGT 2378 sc-eQTL 4.13e-04 -0.286 0.0798 0.684 cMono_S100A L2
ENSG00000116791 CRYZ -532818 sc-eQTL 8.86e-01 -0.0138 0.0959 0.694 gdT L2
ENSG00000162623 TYW3 -532562 sc-eQTL 1.58e-01 -0.145 0.102 0.694 gdT L2
ENSG00000254685 FPGT 2378 sc-eQTL 3.42e-02 -0.205 0.0957 0.694 gdT L2
ENSG00000116791 CRYZ -532818 sc-eQTL 6.39e-01 0.0407 0.0865 0.687 intMono L2
ENSG00000162623 TYW3 -532562 sc-eQTL 2.35e-02 -0.212 0.0929 0.687 intMono L2
ENSG00000254685 FPGT 2378 sc-eQTL 6.09e-01 -0.0448 0.0874 0.687 intMono L2
ENSG00000116791 CRYZ -532818 sc-eQTL 3.45e-01 -0.0807 0.0852 0.683 ncMono L2
ENSG00000162623 TYW3 -532562 sc-eQTL 3.75e-01 -0.0846 0.0951 0.683 ncMono L2
ENSG00000254685 FPGT 2378 sc-eQTL 2.24e-01 -0.0995 0.0816 0.683 ncMono L2
ENSG00000116791 CRYZ -532818 sc-eQTL 2.13e-01 0.122 0.0978 0.681 pDC L2
ENSG00000162623 TYW3 -532562 sc-eQTL 1.71e-01 0.132 0.0963 0.681 pDC L2
ENSG00000254685 FPGT 2378 sc-eQTL 4.46e-01 0.0687 0.0899 0.681 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000116791 CRYZ -532818 sc-eQTL 6.18e-01 0.0322 0.0645 0.684 B_Memory LOneK1K
ENSG00000162623 TYW3 -532562 sc-eQTL 9.23e-01 0.00903 0.093 0.684 B_Memory LOneK1K
ENSG00000254685 FPGT 2378 sc-eQTL 1.71e-04 -0.335 0.0876 0.684 B_Memory LOneK1K
ENSG00000116791 CRYZ -532818 sc-eQTL 5.75e-01 -0.039 0.0695 0.684 B_Naive LOneK1K
ENSG00000162623 TYW3 -532562 sc-eQTL 7.10e-01 -0.034 0.0911 0.684 B_Naive LOneK1K
ENSG00000254685 FPGT 2378 sc-eQTL 1.29e-03 -0.28 0.0858 0.684 B_Naive LOneK1K
ENSG00000116791 CRYZ -532818 sc-eQTL 5.35e-01 0.0576 0.0927 0.684 CD14_Mono LOneK1K
ENSG00000162623 TYW3 -532562 sc-eQTL 2.11e-01 -0.105 0.0841 0.684 CD14_Mono LOneK1K
ENSG00000254685 FPGT 2378 sc-eQTL 2.45e-05 -0.317 0.0734 0.684 CD14_Mono LOneK1K
ENSG00000116791 CRYZ -532818 sc-eQTL 7.42e-01 -0.0293 0.0892 0.683 CD16_Mono LOneK1K
ENSG00000162623 TYW3 -532562 sc-eQTL 1.25e-01 -0.139 0.0902 0.683 CD16_Mono LOneK1K
ENSG00000254685 FPGT 2378 sc-eQTL 9.44e-02 -0.14 0.0831 0.683 CD16_Mono LOneK1K
ENSG00000116791 CRYZ -532818 sc-eQTL 6.96e-01 0.0268 0.0684 0.683 NK_CD56dim LOneK1K
ENSG00000162623 TYW3 -532562 sc-eQTL 5.92e-01 0.0431 0.0804 0.683 NK_CD56dim LOneK1K
ENSG00000254685 FPGT 2378 sc-eQTL 5.40e-08 -0.444 0.0787 0.683 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000162620 LRRIQ3 2403 eQTL 9.390000000000001e-110 -0.751 0.0294 0.0479 0.0679 0.319
ENSG00000254685 FPGT 2378 eQTL 1.2e-84 -0.337 0.0156 0.0191 0.0363 0.319

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000162620 LRRIQ3 2403 0.000133 0.000112 3.17e-05 4.19e-05 2.68e-05 4.8e-05 0.000134 2.2e-05 0.000106 7.05e-05 0.000138 6.67e-05 0.000153 5.36e-05 3.44e-05 9.31e-05 5.94e-05 8.86e-05 3.33e-05 2.42e-05 6.77e-05 0.000133 8.94e-05 3.82e-05 0.000145 4.82e-05 6.99e-05 5.21e-05 0.000101 7.59e-05 7.5e-05 7.55e-06 1.16e-05 2.64e-05 3.09e-05 2.01e-05 1.19e-05 1.35e-05 1.9e-05 1.17e-05 9.38e-06 0.000112 1.44e-05 2.27e-06 1.11e-05 1.58e-05 1.65e-05 7.58e-06 4.58e-06
ENSG00000254685 FPGT 2378 0.000134 0.000112 3.17e-05 4.19e-05 2.68e-05 4.8e-05 0.000134 2.22e-05 0.000106 7.05e-05 0.000138 6.7e-05 0.000153 5.45e-05 3.44e-05 9.31e-05 6.07e-05 8.86e-05 3.38e-05 2.42e-05 6.77e-05 0.000133 8.94e-05 3.82e-05 0.000147 4.82e-05 7.04e-05 5.21e-05 0.000101 7.63e-05 7.5e-05 7.55e-06 1.15e-05 2.64e-05 3.09e-05 2.01e-05 1.19e-05 1.35e-05 1.9e-05 1.17e-05 9.38e-06 0.000114 1.44e-05 2.27e-06 1.11e-05 1.58e-05 1.65e-05 7.58e-06 4.74e-06