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Genes within 1Mb (chr1:69345607:C:T):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000066557 LRRC40 -859972 sc-eQTL 5.86e-01 0.0906 0.166 0.06 B L1
ENSG00000116754 SRSF11 -860075 sc-eQTL 4.62e-01 -0.0948 0.129 0.06 B L1
ENSG00000066557 LRRC40 -859972 sc-eQTL 2.73e-01 0.153 0.14 0.06 CD4T L1
ENSG00000116754 SRSF11 -860075 sc-eQTL 6.60e-01 -0.0485 0.11 0.06 CD4T L1
ENSG00000066557 LRRC40 -859972 sc-eQTL 5.32e-01 0.0994 0.159 0.06 CD8T L1
ENSG00000116754 SRSF11 -860075 sc-eQTL 2.94e-01 -0.139 0.132 0.06 CD8T L1
ENSG00000066557 LRRC40 -859972 sc-eQTL 1.17e-01 0.311 0.197 0.063 DC L1
ENSG00000116754 SRSF11 -860075 sc-eQTL 9.69e-01 -0.00523 0.133 0.063 DC L1
ENSG00000066557 LRRC40 -859972 sc-eQTL 9.18e-02 -0.316 0.187 0.06 Mono L1
ENSG00000116754 SRSF11 -860075 sc-eQTL 3.16e-01 -0.109 0.109 0.06 Mono L1
ENSG00000066557 LRRC40 -859972 sc-eQTL 1.44e-02 0.385 0.156 0.06 NK L1
ENSG00000116754 SRSF11 -860075 sc-eQTL 8.81e-01 0.0209 0.14 0.06 NK L1
ENSG00000024526 DEPDC1 848386 sc-eQTL 9.05e-01 -0.0108 0.09 0.06 Other_T L1
ENSG00000066557 LRRC40 -859972 sc-eQTL 8.55e-01 -0.0346 0.189 0.06 Other_T L1
ENSG00000116754 SRSF11 -860075 sc-eQTL 7.54e-01 -0.0464 0.148 0.06 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000066557 LRRC40 -859972 sc-eQTL 8.20e-01 -0.0448 0.196 0.066 B_Activated L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 5.70e-01 -0.118 0.208 0.066 B_Activated L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 5.56e-01 0.113 0.191 0.06 B_Intermediate L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 1.25e-01 -0.25 0.162 0.06 B_Intermediate L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 7.36e-01 -0.0672 0.199 0.06 B_Memory L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 4.06e-01 -0.147 0.176 0.06 B_Memory L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 7.97e-01 0.048 0.186 0.06 B_Naive1 L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 2.60e-01 -0.167 0.148 0.06 B_Naive1 L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 7.99e-01 -0.0504 0.197 0.06 B_Naive2 L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 4.53e-01 -0.131 0.174 0.06 B_Naive2 L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 9.23e-01 -0.0184 0.189 0.061 CD4_CTL L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 6.98e-01 -0.0763 0.196 0.061 CD4_CTL L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 9.91e-02 0.258 0.156 0.06 CD4_Naive L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 8.24e-01 -0.0254 0.114 0.06 CD4_Naive L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 8.84e-01 0.027 0.184 0.06 CD4_TCM L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 1.63e-01 -0.19 0.135 0.06 CD4_TCM L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 3.08e-01 -0.191 0.186 0.06 CD4_TEM L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 9.88e-01 0.00244 0.163 0.06 CD4_TEM L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 5.72e-01 0.1 0.177 0.06 CD8_CTL L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 2.81e-01 -0.181 0.168 0.06 CD8_CTL L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 3.43e-01 -0.184 0.194 0.06 CD8_Naive L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 4.99e-01 -0.098 0.145 0.06 CD8_Naive L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 4.97e-02 0.408 0.206 0.06 CD8_TCM L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 8.22e-02 0.333 0.19 0.06 CD8_TCM L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 6.79e-01 0.0834 0.201 0.055 CD8_TEM L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 8.18e-01 -0.0432 0.188 0.055 CD8_TEM L2
ENSG00000024526 DEPDC1 848386 sc-eQTL 1.64e-02 0.166 0.0687 0.058 MAIT L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 8.61e-01 -0.0339 0.194 0.058 MAIT L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 2.73e-01 -0.208 0.19 0.058 MAIT L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 2.16e-01 -0.258 0.208 0.058 NK_CD56bright L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 7.57e-01 0.0569 0.184 0.058 NK_CD56bright L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 2.15e-01 0.212 0.171 0.06 NK_CD56dim L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 5.47e-01 -0.1 0.167 0.06 NK_CD56dim L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 7.08e-03 0.538 0.198 0.062 NK_HLA L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 5.04e-01 -0.122 0.181 0.062 NK_HLA L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 2.69e-01 0.217 0.196 0.06 NK_cytokine L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 6.01e-01 0.0881 0.168 0.06 NK_cytokine L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 1.77e-01 0.313 0.23 0.067 PB L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 5.58e-01 0.123 0.209 0.067 PB L2
ENSG00000024526 DEPDC1 848386 sc-eQTL 5.65e-01 -0.0695 0.12 0.061 Pro_T L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 6.43e-01 -0.0911 0.196 0.061 Pro_T L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 2.63e-01 0.19 0.169 0.061 Pro_T L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 6.72e-01 -0.0846 0.2 0.06 Treg L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 4.29e-01 0.132 0.167 0.06 Treg L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 7.37e-03 0.521 0.192 0.059 cDC L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 9.20e-01 0.0147 0.147 0.059 cDC L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 7.96e-03 -0.486 0.182 0.06 cMono_IL1B L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 1.77e-02 -0.288 0.121 0.06 cMono_IL1B L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 4.12e-01 0.164 0.199 0.06 cMono_S100A L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 5.95e-01 0.0758 0.142 0.06 cMono_S100A L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 1.65e-01 -0.34 0.244 0.052 gdT L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 6.70e-01 -0.0997 0.233 0.052 gdT L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 5.74e-01 -0.108 0.192 0.06 intMono L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 5.04e-01 -0.112 0.167 0.06 intMono L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 6.24e-01 -0.101 0.207 0.054 ncMono L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 7.13e-01 -0.0586 0.159 0.054 ncMono L2
ENSG00000066557 LRRC40 -859972 sc-eQTL 5.11e-01 -0.148 0.225 0.056 pDC L2
ENSG00000116754 SRSF11 -860075 sc-eQTL 5.25e-01 -0.121 0.19 0.056 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000066557 LRRC40 -859972 sc-eQTL 8.05e-01 -0.0452 0.183 0.06 B_Memory LOneK1K
ENSG00000116754 SRSF11 -860075 sc-eQTL 7.36e-02 -0.286 0.159 0.06 B_Memory LOneK1K
ENSG00000066557 LRRC40 -859972 sc-eQTL 9.89e-01 -0.00244 0.18 0.06 B_Naive LOneK1K
ENSG00000116754 SRSF11 -860075 sc-eQTL 2.97e-01 -0.16 0.153 0.06 B_Naive LOneK1K
ENSG00000066557 LRRC40 -859972 sc-eQTL 9.78e-02 -0.309 0.186 0.06 CD14_Mono LOneK1K
ENSG00000116754 SRSF11 -860075 sc-eQTL 3.27e-01 -0.11 0.112 0.06 CD14_Mono LOneK1K
ENSG00000066557 LRRC40 -859972 sc-eQTL 6.08e-01 -0.0981 0.191 0.06 CD16_Mono LOneK1K
ENSG00000116754 SRSF11 -860075 sc-eQTL 6.53e-01 -0.0665 0.148 0.06 CD16_Mono LOneK1K
ENSG00000066557 LRRC40 -859972 sc-eQTL 2.91e-03 0.489 0.162 0.06 NK_CD56dim LOneK1K
ENSG00000116754 SRSF11 -860075 sc-eQTL 9.58e-01 0.00764 0.144 0.06 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000033122 LRRC7 -222654 eQTL 0.0191 0.187 0.0796 0.0 0.0 0.0702

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000033122 LRRC7 -222654 1.65e-06 2.16e-06 2.5e-07 1.35e-06 4.74e-07 6.95e-07 1.2e-06 4.75e-07 1.78e-06 7.98e-07 1.87e-06 1.34e-06 2.68e-06 6.19e-07 4.52e-07 1.15e-06 1.03e-06 1.33e-06 5.56e-07 7.37e-07 7.02e-07 1.96e-06 1.56e-06 9.28e-07 2.49e-06 1.08e-06 1.16e-06 1.15e-06 1.72e-06 1.53e-06 7.56e-07 2.62e-07 4.61e-07 8e-07 9.62e-07 6.23e-07 6.6e-07 3.86e-07 5.99e-07 1.85e-07 3.05e-07 2.32e-06 4.23e-07 1.66e-07 3.75e-07 2.93e-07 4.79e-07 2.2e-07 2.3e-07