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Genes within 1Mb (chr1:69230708:C:T):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000066557 LRRC40 -974871 sc-eQTL 7.60e-01 0.0258 0.0842 0.712 B L1
ENSG00000116754 SRSF11 -974974 sc-eQTL 9.22e-01 0.0064 0.0653 0.712 B L1
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.45e-02 -0.159 0.07 0.712 CD4T L1
ENSG00000116754 SRSF11 -974974 sc-eQTL 8.72e-01 -0.009 0.0557 0.712 CD4T L1
ENSG00000066557 LRRC40 -974871 sc-eQTL 7.05e-01 -0.0303 0.0798 0.712 CD8T L1
ENSG00000116754 SRSF11 -974974 sc-eQTL 4.41e-01 -0.0512 0.0664 0.712 CD8T L1
ENSG00000066557 LRRC40 -974871 sc-eQTL 1.86e-02 0.239 0.101 0.705 DC L1
ENSG00000116729 WLS 997588 sc-eQTL 1.50e-01 0.122 0.0847 0.705 DC L1
ENSG00000116754 SRSF11 -974974 sc-eQTL 3.19e-01 0.0679 0.068 0.705 DC L1
ENSG00000066557 LRRC40 -974871 sc-eQTL 7.72e-01 0.0269 0.0928 0.712 Mono L1
ENSG00000116729 WLS 997588 sc-eQTL 1.19e-02 0.197 0.0775 0.712 Mono L1
ENSG00000116754 SRSF11 -974974 sc-eQTL 5.25e-01 0.0342 0.0537 0.712 Mono L1
ENSG00000066557 LRRC40 -974871 sc-eQTL 1.67e-01 0.111 0.08 0.71 NK L1
ENSG00000116754 SRSF11 -974974 sc-eQTL 7.05e-01 0.0269 0.0709 0.71 NK L1
ENSG00000024526 DEPDC1 733487 sc-eQTL 5.19e-02 0.0881 0.045 0.712 Other_T L1
ENSG00000066557 LRRC40 -974871 sc-eQTL 3.68e-01 0.0858 0.0951 0.712 Other_T L1
ENSG00000116754 SRSF11 -974974 sc-eQTL 2.78e-01 -0.0812 0.0746 0.712 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000066557 LRRC40 -974871 sc-eQTL 7.03e-02 0.181 0.0992 0.712 B_Activated L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 6.76e-01 0.0444 0.106 0.712 B_Activated L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 1.32e-01 0.147 0.0974 0.712 B_Intermediate L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 4.16e-01 0.0679 0.0833 0.712 B_Intermediate L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 1.40e-01 -0.151 0.102 0.709 B_Memory L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 6.27e-01 0.0442 0.0908 0.709 B_Memory L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.94e-02 0.202 0.0922 0.712 B_Naive1 L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 8.62e-01 0.0129 0.0741 0.712 B_Naive1 L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.53e-01 -0.112 0.0979 0.71 B_Naive2 L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 3.76e-01 -0.0768 0.0866 0.71 B_Naive2 L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 8.86e-02 -0.17 0.0994 0.718 CD4_CTL L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 4.93e-01 -0.0712 0.104 0.718 CD4_CTL L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 7.55e-02 -0.142 0.0793 0.712 CD4_Naive L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 2.47e-01 -0.067 0.0577 0.712 CD4_Naive L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 9.06e-01 0.0111 0.0941 0.712 CD4_TCM L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 3.05e-01 0.0712 0.0693 0.712 CD4_TCM L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 1.65e-01 -0.13 0.0935 0.712 CD4_TEM L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 7.41e-01 0.0272 0.082 0.712 CD4_TEM L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 1.73e-01 0.119 0.0868 0.712 CD8_CTL L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 1.24e-01 -0.127 0.0821 0.712 CD8_CTL L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 7.83e-01 -0.0275 0.0996 0.712 CD8_Naive L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 1.79e-01 0.0995 0.0738 0.712 CD8_Naive L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 1.84e-01 -0.139 0.104 0.718 CD8_TCM L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 2.63e-01 -0.108 0.0959 0.718 CD8_TCM L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.47e-01 -0.114 0.0978 0.712 CD8_TEM L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 2.11e-01 -0.114 0.0912 0.712 CD8_TEM L2
ENSG00000024526 DEPDC1 733487 sc-eQTL 5.01e-01 0.0243 0.0361 0.719 MAIT L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 4.78e-01 -0.0713 0.1 0.719 MAIT L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 1.07e-02 -0.25 0.097 0.719 MAIT L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 9.10e-01 -0.0117 0.103 0.707 NK_CD56bright L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 2.67e-01 -0.101 0.0906 0.707 NK_CD56bright L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.14e-01 0.105 0.0844 0.711 NK_CD56dim L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 4.50e-02 0.165 0.0816 0.711 NK_CD56dim L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.21e-01 0.122 0.0994 0.712 NK_HLA L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 5.80e-01 -0.0498 0.0899 0.712 NK_HLA L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.64e-02 0.212 0.0949 0.711 NK_cytokine L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 2.48e-01 -0.0947 0.0818 0.711 NK_cytokine L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.92e-01 -0.126 0.119 0.7 PB L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 2.44e-02 -0.24 0.105 0.7 PB L2
ENSG00000024526 DEPDC1 733487 sc-eQTL 1.83e-01 0.0778 0.0582 0.711 Pro_T L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.07e-01 0.12 0.0948 0.711 Pro_T L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 1.63e-01 -0.115 0.0818 0.711 Pro_T L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 9.82e-01 0.00235 0.102 0.712 Treg L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 7.78e-01 -0.0241 0.0852 0.712 Treg L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 5.84e-01 0.0548 0.0999 0.717 cDC L2
ENSG00000116729 WLS 997588 sc-eQTL 8.16e-02 0.158 0.0903 0.717 cDC L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 6.07e-02 0.14 0.0741 0.717 cDC L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 5.72e-01 0.0525 0.0929 0.712 cMono_IL1B L2
ENSG00000116729 WLS 997588 sc-eQTL 4.38e-03 0.229 0.0794 0.712 cMono_IL1B L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 9.12e-01 0.00684 0.0615 0.712 cMono_IL1B L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 3.77e-01 -0.0887 0.1 0.712 cMono_S100A L2
ENSG00000116729 WLS 997588 sc-eQTL 5.73e-02 0.144 0.0752 0.712 cMono_S100A L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 6.68e-02 0.131 0.0713 0.712 cMono_S100A L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.51e-01 0.139 0.121 0.703 gdT L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 8.88e-01 0.0163 0.115 0.703 gdT L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.90e-01 0.104 0.0978 0.713 intMono L2
ENSG00000116729 WLS 997588 sc-eQTL 8.35e-01 0.0193 0.0925 0.713 intMono L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 7.82e-01 -0.0237 0.0857 0.713 intMono L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 7.47e-01 -0.0328 0.102 0.71 ncMono L2
ENSG00000116729 WLS 997588 sc-eQTL 2.36e-01 0.104 0.0876 0.71 ncMono L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 8.73e-01 0.0125 0.0783 0.71 ncMono L2
ENSG00000066557 LRRC40 -974871 sc-eQTL 1.31e-01 0.168 0.111 0.723 pDC L2
ENSG00000116729 WLS 997588 sc-eQTL 8.70e-01 -0.0135 0.0825 0.723 pDC L2
ENSG00000116754 SRSF11 -974974 sc-eQTL 2.14e-01 0.117 0.0941 0.723 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000066557 LRRC40 -974871 sc-eQTL 9.26e-01 -0.00867 0.0935 0.712 B_Memory LOneK1K
ENSG00000116754 SRSF11 -974974 sc-eQTL 7.73e-01 0.0237 0.082 0.712 B_Memory LOneK1K
ENSG00000066557 LRRC40 -974871 sc-eQTL 2.67e-01 0.101 0.0905 0.712 B_Naive LOneK1K
ENSG00000116754 SRSF11 -974974 sc-eQTL 5.25e-01 -0.049 0.077 0.712 B_Naive LOneK1K
ENSG00000066557 LRRC40 -974871 sc-eQTL 9.35e-01 -0.00772 0.0938 0.712 CD14_Mono LOneK1K
ENSG00000116729 WLS 997588 sc-eQTL 4.51e-03 0.209 0.0728 0.712 CD14_Mono LOneK1K
ENSG00000116754 SRSF11 -974974 sc-eQTL 4.32e-01 0.0443 0.0562 0.712 CD14_Mono LOneK1K
ENSG00000066557 LRRC40 -974871 sc-eQTL 9.90e-01 0.00125 0.0964 0.709 CD16_Mono LOneK1K
ENSG00000116729 WLS 997588 sc-eQTL 3.86e-01 0.0793 0.0914 0.709 CD16_Mono LOneK1K
ENSG00000116754 SRSF11 -974974 sc-eQTL 8.63e-01 0.0129 0.0746 0.709 CD16_Mono LOneK1K
ENSG00000066557 LRRC40 -974871 sc-eQTL 7.51e-02 0.15 0.0837 0.711 NK_CD56dim LOneK1K
ENSG00000116754 SRSF11 -974974 sc-eQTL 6.39e-01 0.0345 0.0733 0.711 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000033122 LRRC7 -337553 eQTL 0.0247 -0.0977 0.0434 0.0 0.0 0.293
ENSG00000116729 WLS 997588 eQTL 0.0116 0.0658 0.026 0.0 0.0 0.293

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina