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Genes within 1Mb (chr1:65873365:C:T):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 805611 sc-eQTL 7.55e-01 0.0172 0.055 0.365 B L1
ENSG00000184588 PDE4B 80851 sc-eQTL 3.46e-01 0.0542 0.0574 0.365 B L1
ENSG00000213625 LEPROT 452778 sc-eQTL 9.22e-01 0.00689 0.0703 0.365 B L1
ENSG00000162434 JAK1 805611 sc-eQTL 3.90e-02 0.112 0.0538 0.365 CD4T L1
ENSG00000184588 PDE4B 80851 sc-eQTL 3.43e-01 -0.0614 0.0646 0.365 CD4T L1
ENSG00000213625 LEPROT 452778 sc-eQTL 1.55e-01 0.121 0.0845 0.365 CD4T L1
ENSG00000116678 LEPR 452713 sc-eQTL 3.23e-01 -0.0893 0.0901 0.365 CD8T L1
ENSG00000162434 JAK1 805611 sc-eQTL 3.84e-03 0.201 0.0687 0.365 CD8T L1
ENSG00000184588 PDE4B 80851 sc-eQTL 5.20e-01 -0.0385 0.0597 0.365 CD8T L1
ENSG00000213625 LEPROT 452778 sc-eQTL 4.57e-01 0.0692 0.0927 0.365 CD8T L1
ENSG00000116678 LEPR 452713 sc-eQTL 4.83e-01 0.0621 0.0882 0.365 DC L1
ENSG00000162433 AK4 725816 sc-eQTL 3.10e-01 0.0754 0.0741 0.365 DC L1
ENSG00000162434 JAK1 805611 sc-eQTL 4.08e-01 0.0512 0.0617 0.365 DC L1
ENSG00000184588 PDE4B 80851 sc-eQTL 1.44e-01 0.0699 0.0476 0.365 DC L1
ENSG00000213625 LEPROT 452778 sc-eQTL 5.26e-01 0.0556 0.0875 0.365 DC L1
ENSG00000285079 AL513493.1 169403 sc-eQTL 7.42e-01 -0.0156 0.0472 0.365 DC L1
ENSG00000116678 LEPR 452713 sc-eQTL 4.78e-01 0.0638 0.0898 0.365 Mono L1
ENSG00000162433 AK4 725816 sc-eQTL 2.01e-01 -0.105 0.082 0.365 Mono L1
ENSG00000162434 JAK1 805611 sc-eQTL 3.82e-01 0.0513 0.0586 0.365 Mono L1
ENSG00000184588 PDE4B 80851 sc-eQTL 4.48e-01 0.0247 0.0324 0.365 Mono L1
ENSG00000213625 LEPROT 452778 sc-eQTL 9.11e-01 0.0065 0.0581 0.365 Mono L1
ENSG00000116678 LEPR 452713 sc-eQTL 1.41e-01 0.128 0.0865 0.367 NK L1
ENSG00000162434 JAK1 805611 sc-eQTL 2.58e-02 0.0911 0.0406 0.367 NK L1
ENSG00000184588 PDE4B 80851 sc-eQTL 4.02e-01 -0.047 0.0559 0.367 NK L1
ENSG00000213625 LEPROT 452778 sc-eQTL 8.91e-01 0.0129 0.0937 0.367 NK L1
ENSG00000162434 JAK1 805611 sc-eQTL 4.53e-01 0.0448 0.0596 0.365 Other_T L1
ENSG00000184588 PDE4B 80851 sc-eQTL 2.44e-01 0.0755 0.0646 0.365 Other_T L1
ENSG00000213625 LEPROT 452778 sc-eQTL 3.94e-01 0.0799 0.0936 0.365 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 805611 sc-eQTL 3.23e-01 0.0956 0.0965 0.39 B_Activated L2
ENSG00000184588 PDE4B 80851 sc-eQTL 7.04e-01 -0.0292 0.0768 0.39 B_Activated L2
ENSG00000213625 LEPROT 452778 sc-eQTL 2.42e-01 -0.118 0.101 0.39 B_Activated L2
ENSG00000162434 JAK1 805611 sc-eQTL 6.27e-01 0.0381 0.0784 0.367 B_Intermediate L2
ENSG00000184588 PDE4B 80851 sc-eQTL 4.04e-01 0.0534 0.0638 0.367 B_Intermediate L2
ENSG00000213625 LEPROT 452778 sc-eQTL 9.37e-01 -0.00724 0.0919 0.367 B_Intermediate L2
ENSG00000162434 JAK1 805611 sc-eQTL 3.96e-01 0.0684 0.0804 0.366 B_Memory L2
ENSG00000184588 PDE4B 80851 sc-eQTL 6.58e-02 0.151 0.0816 0.366 B_Memory L2
ENSG00000213625 LEPROT 452778 sc-eQTL 6.37e-01 0.0442 0.0936 0.366 B_Memory L2
ENSG00000162434 JAK1 805611 sc-eQTL 7.01e-01 0.0273 0.0711 0.365 B_Naive1 L2
ENSG00000184588 PDE4B 80851 sc-eQTL 2.88e-01 0.0729 0.0684 0.365 B_Naive1 L2
ENSG00000213625 LEPROT 452778 sc-eQTL 5.44e-01 -0.0563 0.0928 0.365 B_Naive1 L2
ENSG00000162434 JAK1 805611 sc-eQTL 5.75e-01 -0.042 0.0747 0.367 B_Naive2 L2
ENSG00000184588 PDE4B 80851 sc-eQTL 5.86e-01 0.0322 0.0591 0.367 B_Naive2 L2
ENSG00000213625 LEPROT 452778 sc-eQTL 5.68e-01 0.0516 0.0901 0.367 B_Naive2 L2
ENSG00000162434 JAK1 805611 sc-eQTL 5.10e-01 0.0563 0.0854 0.361 CD4_CTL L2
ENSG00000184588 PDE4B 80851 sc-eQTL 3.03e-01 -0.0778 0.0754 0.361 CD4_CTL L2
ENSG00000213625 LEPROT 452778 sc-eQTL 1.65e-01 0.136 0.0977 0.361 CD4_CTL L2
ENSG00000162434 JAK1 805611 sc-eQTL 3.77e-02 0.11 0.0526 0.365 CD4_Naive L2
ENSG00000184588 PDE4B 80851 sc-eQTL 2.92e-01 -0.0701 0.0663 0.365 CD4_Naive L2
ENSG00000213625 LEPROT 452778 sc-eQTL 2.45e-01 0.1 0.0858 0.365 CD4_Naive L2
ENSG00000162434 JAK1 805611 sc-eQTL 3.74e-01 0.0538 0.0603 0.365 CD4_TCM L2
ENSG00000184588 PDE4B 80851 sc-eQTL 4.98e-01 -0.0469 0.0691 0.365 CD4_TCM L2
ENSG00000213625 LEPROT 452778 sc-eQTL 5.59e-01 -0.0512 0.0876 0.365 CD4_TCM L2
ENSG00000162434 JAK1 805611 sc-eQTL 4.44e-01 0.0611 0.0797 0.365 CD4_TEM L2
ENSG00000184588 PDE4B 80851 sc-eQTL 6.43e-01 -0.0342 0.0737 0.365 CD4_TEM L2
ENSG00000213625 LEPROT 452778 sc-eQTL 4.65e-01 0.0694 0.0947 0.365 CD4_TEM L2
ENSG00000116678 LEPR 452713 sc-eQTL 4.19e-02 -0.178 0.0871 0.365 CD8_CTL L2
ENSG00000162434 JAK1 805611 sc-eQTL 8.77e-02 0.126 0.0733 0.365 CD8_CTL L2
ENSG00000184588 PDE4B 80851 sc-eQTL 8.59e-01 0.0121 0.0683 0.365 CD8_CTL L2
ENSG00000213625 LEPROT 452778 sc-eQTL 2.67e-01 0.1 0.09 0.365 CD8_CTL L2
ENSG00000116678 LEPR 452713 sc-eQTL 2.96e-01 -0.0931 0.0889 0.365 CD8_Naive L2
ENSG00000162434 JAK1 805611 sc-eQTL 8.48e-02 0.128 0.0738 0.365 CD8_Naive L2
ENSG00000184588 PDE4B 80851 sc-eQTL 1.91e-01 -0.0816 0.0622 0.365 CD8_Naive L2
ENSG00000213625 LEPROT 452778 sc-eQTL 7.64e-01 0.0274 0.091 0.365 CD8_Naive L2
ENSG00000116678 LEPR 452713 sc-eQTL 2.40e-01 0.106 0.0904 0.363 CD8_TCM L2
ENSG00000162434 JAK1 805611 sc-eQTL 2.28e-01 0.0949 0.0785 0.363 CD8_TCM L2
ENSG00000184588 PDE4B 80851 sc-eQTL 9.52e-02 -0.144 0.0861 0.363 CD8_TCM L2
ENSG00000213625 LEPROT 452778 sc-eQTL 7.53e-01 -0.0309 0.0983 0.363 CD8_TCM L2
ENSG00000116678 LEPR 452713 sc-eQTL 5.14e-01 0.0534 0.0816 0.361 CD8_TEM L2
ENSG00000162434 JAK1 805611 sc-eQTL 1.54e-01 0.132 0.0919 0.361 CD8_TEM L2
ENSG00000184588 PDE4B 80851 sc-eQTL 4.23e-01 0.063 0.0784 0.361 CD8_TEM L2
ENSG00000213625 LEPROT 452778 sc-eQTL 5.93e-01 -0.0509 0.0952 0.361 CD8_TEM L2
ENSG00000162434 JAK1 805611 sc-eQTL 5.25e-01 0.051 0.08 0.364 MAIT L2
ENSG00000184588 PDE4B 80851 sc-eQTL 1.62e-01 0.0956 0.0681 0.364 MAIT L2
ENSG00000213625 LEPROT 452778 sc-eQTL 9.12e-01 -0.0102 0.0922 0.364 MAIT L2
ENSG00000116678 LEPR 452713 sc-eQTL 8.46e-01 0.0167 0.086 0.367 NK_CD56bright L2
ENSG00000162434 JAK1 805611 sc-eQTL 7.11e-01 0.0219 0.0589 0.367 NK_CD56bright L2
ENSG00000184588 PDE4B 80851 sc-eQTL 4.63e-01 0.0519 0.0706 0.367 NK_CD56bright L2
ENSG00000213625 LEPROT 452778 sc-eQTL 1.99e-01 0.124 0.0964 0.367 NK_CD56bright L2
ENSG00000116678 LEPR 452713 sc-eQTL 3.34e-01 0.0888 0.0917 0.366 NK_CD56dim L2
ENSG00000162434 JAK1 805611 sc-eQTL 1.17e-01 0.0752 0.0478 0.366 NK_CD56dim L2
ENSG00000184588 PDE4B 80851 sc-eQTL 5.78e-01 -0.0391 0.0701 0.366 NK_CD56dim L2
ENSG00000213625 LEPROT 452778 sc-eQTL 2.90e-01 -0.103 0.0969 0.366 NK_CD56dim L2
ENSG00000116678 LEPR 452713 sc-eQTL 4.01e-01 -0.0671 0.0798 0.365 NK_HLA L2
ENSG00000162434 JAK1 805611 sc-eQTL 7.78e-01 -0.0175 0.0622 0.365 NK_HLA L2
ENSG00000184588 PDE4B 80851 sc-eQTL 2.35e-01 -0.0898 0.0755 0.365 NK_HLA L2
ENSG00000213625 LEPROT 452778 sc-eQTL 6.82e-01 -0.0396 0.0964 0.365 NK_HLA L2
ENSG00000116678 LEPR 452713 sc-eQTL 9.77e-02 0.146 0.0878 0.366 NK_cytokine L2
ENSG00000162434 JAK1 805611 sc-eQTL 6.15e-02 0.0959 0.051 0.366 NK_cytokine L2
ENSG00000184588 PDE4B 80851 sc-eQTL 8.39e-01 0.0164 0.0806 0.366 NK_cytokine L2
ENSG00000213625 LEPROT 452778 sc-eQTL 1.60e-01 0.131 0.0931 0.366 NK_cytokine L2
ENSG00000162434 JAK1 805611 sc-eQTL 8.31e-01 -0.017 0.0797 0.407 PB L2
ENSG00000184588 PDE4B 80851 sc-eQTL 3.94e-01 0.0863 0.101 0.407 PB L2
ENSG00000213625 LEPROT 452778 sc-eQTL 1.65e-01 0.155 0.111 0.407 PB L2
ENSG00000162434 JAK1 805611 sc-eQTL 1.69e-01 -0.0837 0.0607 0.363 Pro_T L2
ENSG00000184588 PDE4B 80851 sc-eQTL 3.92e-01 0.0641 0.0747 0.363 Pro_T L2
ENSG00000213625 LEPROT 452778 sc-eQTL 4.59e-01 0.0703 0.0948 0.363 Pro_T L2
ENSG00000162434 JAK1 805611 sc-eQTL 2.19e-02 0.17 0.0735 0.365 Treg L2
ENSG00000184588 PDE4B 80851 sc-eQTL 8.19e-01 -0.0156 0.0679 0.365 Treg L2
ENSG00000213625 LEPROT 452778 sc-eQTL 2.78e-01 0.105 0.0963 0.365 Treg L2
ENSG00000116678 LEPR 452713 sc-eQTL 4.51e-01 0.069 0.0913 0.368 cDC L2
ENSG00000162433 AK4 725816 sc-eQTL 4.40e-01 0.0625 0.0807 0.368 cDC L2
ENSG00000162434 JAK1 805611 sc-eQTL 6.25e-02 0.14 0.0747 0.368 cDC L2
ENSG00000184588 PDE4B 80851 sc-eQTL 5.02e-01 0.034 0.0506 0.368 cDC L2
ENSG00000213625 LEPROT 452778 sc-eQTL 6.61e-01 0.0404 0.0919 0.368 cDC L2
ENSG00000285079 AL513493.1 169403 sc-eQTL 3.36e-01 -0.0318 0.0329 0.368 cDC L2
ENSG00000116678 LEPR 452713 sc-eQTL 2.00e-01 0.117 0.0906 0.365 cMono_IL1B L2
ENSG00000162433 AK4 725816 sc-eQTL 5.11e-01 -0.055 0.0836 0.365 cMono_IL1B L2
ENSG00000162434 JAK1 805611 sc-eQTL 3.30e-01 0.0741 0.076 0.365 cMono_IL1B L2
ENSG00000184588 PDE4B 80851 sc-eQTL 7.53e-01 0.0133 0.0422 0.365 cMono_IL1B L2
ENSG00000213625 LEPROT 452778 sc-eQTL 1.03e-01 0.1 0.0611 0.365 cMono_IL1B L2
ENSG00000116678 LEPR 452713 sc-eQTL 7.74e-01 -0.0256 0.0891 0.365 cMono_S100A L2
ENSG00000162433 AK4 725816 sc-eQTL 7.11e-01 -0.0313 0.0845 0.365 cMono_S100A L2
ENSG00000162434 JAK1 805611 sc-eQTL 7.93e-01 0.0204 0.078 0.365 cMono_S100A L2
ENSG00000184588 PDE4B 80851 sc-eQTL 6.34e-01 0.021 0.0441 0.365 cMono_S100A L2
ENSG00000213625 LEPROT 452778 sc-eQTL 7.20e-01 0.0262 0.0729 0.365 cMono_S100A L2
ENSG00000162434 JAK1 805611 sc-eQTL 8.69e-01 0.0181 0.11 0.333 gdT L2
ENSG00000184588 PDE4B 80851 sc-eQTL 9.03e-01 -0.00776 0.0638 0.333 gdT L2
ENSG00000213625 LEPROT 452778 sc-eQTL 9.87e-01 -0.00195 0.115 0.333 gdT L2
ENSG00000116678 LEPR 452713 sc-eQTL 9.77e-01 -0.00261 0.0889 0.373 intMono L2
ENSG00000162433 AK4 725816 sc-eQTL 9.50e-02 -0.139 0.0831 0.373 intMono L2
ENSG00000162434 JAK1 805611 sc-eQTL 8.22e-01 -0.0174 0.0774 0.373 intMono L2
ENSG00000184588 PDE4B 80851 sc-eQTL 8.66e-01 0.00753 0.0447 0.373 intMono L2
ENSG00000213625 LEPROT 452778 sc-eQTL 5.70e-01 -0.0424 0.0746 0.373 intMono L2
ENSG00000116678 LEPR 452713 sc-eQTL 5.15e-01 -0.0564 0.0865 0.362 ncMono L2
ENSG00000162433 AK4 725816 sc-eQTL 1.58e-01 0.109 0.0768 0.362 ncMono L2
ENSG00000162434 JAK1 805611 sc-eQTL 8.42e-01 0.0124 0.0625 0.362 ncMono L2
ENSG00000184588 PDE4B 80851 sc-eQTL 3.07e-01 -0.0507 0.0495 0.362 ncMono L2
ENSG00000213625 LEPROT 452778 sc-eQTL 4.09e-01 -0.0732 0.0885 0.362 ncMono L2
ENSG00000116678 LEPR 452713 sc-eQTL 7.82e-01 -0.0254 0.0918 0.362 pDC L2
ENSG00000162433 AK4 725816 sc-eQTL 4.35e-01 -0.0468 0.0598 0.362 pDC L2
ENSG00000162434 JAK1 805611 sc-eQTL 3.97e-01 -0.0677 0.0798 0.362 pDC L2
ENSG00000184588 PDE4B 80851 sc-eQTL 2.21e-01 0.0854 0.0694 0.362 pDC L2
ENSG00000213625 LEPROT 452778 sc-eQTL 4.17e-01 -0.0806 0.099 0.362 pDC L2
ENSG00000285079 AL513493.1 169403 sc-eQTL 2.88e-01 -0.0795 0.0746 0.362 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 805611 sc-eQTL 2.80e-01 0.0759 0.07 0.365 B_Memory LOneK1K
ENSG00000184588 PDE4B 80851 sc-eQTL 1.50e-01 0.0829 0.0574 0.365 B_Memory LOneK1K
ENSG00000213625 LEPROT 452778 sc-eQTL 7.50e-01 -0.0288 0.0901 0.365 B_Memory LOneK1K
ENSG00000162434 JAK1 805611 sc-eQTL 7.84e-01 0.0188 0.0685 0.365 B_Naive LOneK1K
ENSG00000184588 PDE4B 80851 sc-eQTL 3.40e-01 0.0587 0.0614 0.365 B_Naive LOneK1K
ENSG00000213625 LEPROT 452778 sc-eQTL 8.66e-01 0.0147 0.0867 0.365 B_Naive LOneK1K
ENSG00000116678 LEPR 452713 sc-eQTL 5.05e-01 0.0596 0.0891 0.365 CD14_Mono LOneK1K
ENSG00000162433 AK4 725816 sc-eQTL 2.93e-01 -0.0898 0.0852 0.365 CD14_Mono LOneK1K
ENSG00000162434 JAK1 805611 sc-eQTL 4.68e-01 0.0519 0.0714 0.365 CD14_Mono LOneK1K
ENSG00000184588 PDE4B 80851 sc-eQTL 9.97e-01 0.000156 0.0364 0.365 CD14_Mono LOneK1K
ENSG00000213625 LEPROT 452778 sc-eQTL 1.59e-01 0.0843 0.0596 0.365 CD14_Mono LOneK1K
ENSG00000116678 LEPR 452713 sc-eQTL 7.51e-01 -0.0283 0.0892 0.366 CD16_Mono LOneK1K
ENSG00000162433 AK4 725816 sc-eQTL 9.11e-01 0.00902 0.0808 0.366 CD16_Mono LOneK1K
ENSG00000162434 JAK1 805611 sc-eQTL 8.76e-01 0.00851 0.0544 0.366 CD16_Mono LOneK1K
ENSG00000184588 PDE4B 80851 sc-eQTL 4.18e-01 -0.0337 0.0415 0.366 CD16_Mono LOneK1K
ENSG00000213625 LEPROT 452778 sc-eQTL 1.38e-01 -0.112 0.0754 0.366 CD16_Mono LOneK1K
ENSG00000116678 LEPR 452713 sc-eQTL 1.29e-01 0.135 0.0886 0.366 NK_CD56dim LOneK1K
ENSG00000162434 JAK1 805611 sc-eQTL 2.09e-02 0.096 0.0412 0.366 NK_CD56dim LOneK1K
ENSG00000184588 PDE4B 80851 sc-eQTL 3.47e-01 -0.0609 0.0646 0.366 NK_CD56dim LOneK1K
ENSG00000213625 LEPROT 452778 sc-eQTL 9.10e-01 0.0104 0.0924 0.366 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000116675 DNAJC6 625146 pQTL 0.0243 -0.0298 0.0132 0.0 0.0 0.353
ENSG00000116678 LEPR 452713 eQTL 0.00462 0.0672 0.0237 0.0 0.0 0.351
ENSG00000162433 AK4 725816 eQTL 0.0104 -0.0586 0.0228 0.00351 0.0 0.351
ENSG00000226891 LINC01359 870876 eQTL 0.0761 0.0519 0.0292 0.00142 0.0 0.351

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000184588 \N 80851 6.01e-06 6.75e-06 1.24e-06 3.84e-06 2.25e-06 2.55e-06 9.22e-06 1.84e-06 5.83e-06 4.14e-06 9.1e-06 3.71e-06 1.12e-05 2.99e-06 1.57e-06 5.65e-06 3.71e-06 4.46e-06 2.64e-06 2.63e-06 4.39e-06 7.72e-06 6.05e-06 3.26e-06 9.79e-06 3.11e-06 4.16e-06 2.43e-06 7.08e-06 7.61e-06 3.68e-06 9.71e-07 1.31e-06 3.06e-06 2.59e-06 2.36e-06 1.83e-06 1.68e-06 1.79e-06 1.01e-06 1.05e-06 8.21e-06 9.75e-07 2.27e-07 7.75e-07 1.36e-06 1.29e-06 7.51e-07 4.72e-07