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Genes within 1Mb (chr1:65868977:T:C):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 801223 sc-eQTL 3.12e-01 -0.0566 0.0559 0.447 B L1
ENSG00000184588 PDE4B 76463 sc-eQTL 9.13e-01 -0.00641 0.0585 0.447 B L1
ENSG00000213625 LEPROT 448390 sc-eQTL 4.43e-02 -0.144 0.0709 0.447 B L1
ENSG00000162434 JAK1 801223 sc-eQTL 1.36e-02 -0.135 0.0544 0.447 CD4T L1
ENSG00000184588 PDE4B 76463 sc-eQTL 9.54e-01 -0.00381 0.0658 0.447 CD4T L1
ENSG00000213625 LEPROT 448390 sc-eQTL 6.17e-02 -0.161 0.0855 0.447 CD4T L1
ENSG00000116678 LEPR 448325 sc-eQTL 8.90e-01 -0.0125 0.0906 0.447 CD8T L1
ENSG00000162434 JAK1 801223 sc-eQTL 4.86e-02 -0.138 0.0696 0.447 CD8T L1
ENSG00000184588 PDE4B 76463 sc-eQTL 8.36e-01 -0.0124 0.06 0.447 CD8T L1
ENSG00000213625 LEPROT 448390 sc-eQTL 1.71e-01 -0.127 0.0927 0.447 CD8T L1
ENSG00000116678 LEPR 448325 sc-eQTL 5.87e-01 -0.0499 0.0917 0.446 DC L1
ENSG00000162433 AK4 721428 sc-eQTL 7.98e-01 -0.0197 0.0772 0.446 DC L1
ENSG00000162434 JAK1 801223 sc-eQTL 2.45e-01 -0.0746 0.064 0.446 DC L1
ENSG00000184588 PDE4B 76463 sc-eQTL 5.04e-01 -0.0333 0.0497 0.446 DC L1
ENSG00000213625 LEPROT 448390 sc-eQTL 5.98e-01 -0.048 0.091 0.446 DC L1
ENSG00000285079 AL513493.1 165015 sc-eQTL 7.78e-01 -0.0139 0.049 0.446 DC L1
ENSG00000116678 LEPR 448325 sc-eQTL 6.54e-01 0.0402 0.0895 0.447 Mono L1
ENSG00000162433 AK4 721428 sc-eQTL 2.21e-01 0.1 0.0816 0.447 Mono L1
ENSG00000162434 JAK1 801223 sc-eQTL 2.81e-01 -0.063 0.0583 0.447 Mono L1
ENSG00000184588 PDE4B 76463 sc-eQTL 1.38e-01 -0.0479 0.0322 0.447 Mono L1
ENSG00000213625 LEPROT 448390 sc-eQTL 2.68e-01 -0.064 0.0577 0.447 Mono L1
ENSG00000116678 LEPR 448325 sc-eQTL 8.60e-02 -0.154 0.0892 0.444 NK L1
ENSG00000162434 JAK1 801223 sc-eQTL 5.46e-02 -0.0813 0.0421 0.444 NK L1
ENSG00000184588 PDE4B 76463 sc-eQTL 1.45e-01 0.0844 0.0576 0.444 NK L1
ENSG00000213625 LEPROT 448390 sc-eQTL 2.17e-01 -0.119 0.0965 0.444 NK L1
ENSG00000162434 JAK1 801223 sc-eQTL 1.77e-01 -0.0796 0.0587 0.447 Other_T L1
ENSG00000184588 PDE4B 76463 sc-eQTL 3.87e-01 -0.0555 0.064 0.447 Other_T L1
ENSG00000213625 LEPROT 448390 sc-eQTL 3.01e-01 -0.0957 0.0924 0.447 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 801223 sc-eQTL 1.01e-01 -0.159 0.0966 0.446 B_Activated L2
ENSG00000184588 PDE4B 76463 sc-eQTL 5.94e-01 -0.0412 0.0772 0.446 B_Activated L2
ENSG00000213625 LEPROT 448390 sc-eQTL 1.61e-01 0.143 0.101 0.446 B_Activated L2
ENSG00000162434 JAK1 801223 sc-eQTL 1.01e-01 -0.129 0.0781 0.446 B_Intermediate L2
ENSG00000184588 PDE4B 76463 sc-eQTL 5.00e-01 -0.0432 0.064 0.446 B_Intermediate L2
ENSG00000213625 LEPROT 448390 sc-eQTL 1.52e-02 -0.222 0.0908 0.446 B_Intermediate L2
ENSG00000162434 JAK1 801223 sc-eQTL 7.64e-01 -0.0238 0.0794 0.448 B_Memory L2
ENSG00000184588 PDE4B 76463 sc-eQTL 2.00e-01 -0.104 0.0808 0.448 B_Memory L2
ENSG00000213625 LEPROT 448390 sc-eQTL 2.51e-01 -0.106 0.092 0.448 B_Memory L2
ENSG00000162434 JAK1 801223 sc-eQTL 7.48e-01 -0.0232 0.0723 0.447 B_Naive1 L2
ENSG00000184588 PDE4B 76463 sc-eQTL 7.98e-01 -0.0178 0.0697 0.447 B_Naive1 L2
ENSG00000213625 LEPROT 448390 sc-eQTL 8.09e-01 -0.0229 0.0944 0.447 B_Naive1 L2
ENSG00000162434 JAK1 801223 sc-eQTL 7.64e-01 0.0228 0.0759 0.448 B_Naive2 L2
ENSG00000184588 PDE4B 76463 sc-eQTL 6.64e-01 -0.0261 0.06 0.448 B_Naive2 L2
ENSG00000213625 LEPROT 448390 sc-eQTL 5.17e-01 -0.0594 0.0915 0.448 B_Naive2 L2
ENSG00000162434 JAK1 801223 sc-eQTL 3.40e-01 -0.0836 0.0874 0.452 CD4_CTL L2
ENSG00000184588 PDE4B 76463 sc-eQTL 5.33e-01 -0.0483 0.0774 0.452 CD4_CTL L2
ENSG00000213625 LEPROT 448390 sc-eQTL 7.51e-02 -0.179 0.0998 0.452 CD4_CTL L2
ENSG00000162434 JAK1 801223 sc-eQTL 1.12e-02 -0.135 0.053 0.447 CD4_Naive L2
ENSG00000184588 PDE4B 76463 sc-eQTL 6.09e-01 0.0345 0.0673 0.447 CD4_Naive L2
ENSG00000213625 LEPROT 448390 sc-eQTL 3.14e-01 -0.0878 0.087 0.447 CD4_Naive L2
ENSG00000162434 JAK1 801223 sc-eQTL 3.97e-02 -0.124 0.06 0.447 CD4_TCM L2
ENSG00000184588 PDE4B 76463 sc-eQTL 8.65e-01 -0.0118 0.0694 0.447 CD4_TCM L2
ENSG00000213625 LEPROT 448390 sc-eQTL 1.49e-01 -0.127 0.0875 0.447 CD4_TCM L2
ENSG00000162434 JAK1 801223 sc-eQTL 6.87e-01 -0.0324 0.0802 0.447 CD4_TEM L2
ENSG00000184588 PDE4B 76463 sc-eQTL 8.04e-01 0.0185 0.0741 0.447 CD4_TEM L2
ENSG00000213625 LEPROT 448390 sc-eQTL 3.86e-02 -0.196 0.0943 0.447 CD4_TEM L2
ENSG00000116678 LEPR 448325 sc-eQTL 2.35e-01 0.108 0.0903 0.447 CD8_CTL L2
ENSG00000162434 JAK1 801223 sc-eQTL 9.55e-02 -0.127 0.0756 0.447 CD8_CTL L2
ENSG00000184588 PDE4B 76463 sc-eQTL 2.74e-01 -0.077 0.0702 0.447 CD8_CTL L2
ENSG00000213625 LEPROT 448390 sc-eQTL 1.90e-01 -0.122 0.0926 0.447 CD8_CTL L2
ENSG00000116678 LEPR 448325 sc-eQTL 9.58e-01 0.0048 0.0903 0.447 CD8_Naive L2
ENSG00000162434 JAK1 801223 sc-eQTL 1.25e-01 -0.115 0.0749 0.447 CD8_Naive L2
ENSG00000184588 PDE4B 76463 sc-eQTL 9.11e-01 -0.00707 0.0633 0.447 CD8_Naive L2
ENSG00000213625 LEPROT 448390 sc-eQTL 6.54e-01 -0.0414 0.0922 0.447 CD8_Naive L2
ENSG00000116678 LEPR 448325 sc-eQTL 3.30e-02 -0.194 0.0905 0.447 CD8_TCM L2
ENSG00000162434 JAK1 801223 sc-eQTL 1.92e-01 -0.104 0.0792 0.447 CD8_TCM L2
ENSG00000184588 PDE4B 76463 sc-eQTL 9.16e-01 0.0092 0.0875 0.447 CD8_TCM L2
ENSG00000213625 LEPROT 448390 sc-eQTL 1.41e-01 -0.146 0.0987 0.447 CD8_TCM L2
ENSG00000116678 LEPR 448325 sc-eQTL 5.48e-01 -0.0493 0.0819 0.452 CD8_TEM L2
ENSG00000162434 JAK1 801223 sc-eQTL 3.02e-01 -0.0957 0.0925 0.452 CD8_TEM L2
ENSG00000184588 PDE4B 76463 sc-eQTL 7.40e-01 0.0262 0.0788 0.452 CD8_TEM L2
ENSG00000213625 LEPROT 448390 sc-eQTL 4.60e-01 -0.0707 0.0954 0.452 CD8_TEM L2
ENSG00000162434 JAK1 801223 sc-eQTL 7.99e-01 -0.0207 0.0812 0.446 MAIT L2
ENSG00000184588 PDE4B 76463 sc-eQTL 8.87e-01 0.00992 0.0695 0.446 MAIT L2
ENSG00000213625 LEPROT 448390 sc-eQTL 9.47e-01 0.00628 0.0936 0.446 MAIT L2
ENSG00000116678 LEPR 448325 sc-eQTL 9.79e-01 0.00234 0.0894 0.444 NK_CD56bright L2
ENSG00000162434 JAK1 801223 sc-eQTL 7.69e-01 -0.018 0.0613 0.444 NK_CD56bright L2
ENSG00000184588 PDE4B 76463 sc-eQTL 5.52e-01 0.0437 0.0735 0.444 NK_CD56bright L2
ENSG00000213625 LEPROT 448390 sc-eQTL 1.18e-01 -0.157 0.1 0.444 NK_CD56bright L2
ENSG00000116678 LEPR 448325 sc-eQTL 3.52e-01 -0.0878 0.0942 0.446 NK_CD56dim L2
ENSG00000162434 JAK1 801223 sc-eQTL 8.35e-02 -0.0851 0.0489 0.446 NK_CD56dim L2
ENSG00000184588 PDE4B 76463 sc-eQTL 1.11e-01 0.115 0.0716 0.446 NK_CD56dim L2
ENSG00000213625 LEPROT 448390 sc-eQTL 6.95e-01 -0.0391 0.0997 0.446 NK_CD56dim L2
ENSG00000116678 LEPR 448325 sc-eQTL 7.28e-01 0.029 0.0833 0.445 NK_HLA L2
ENSG00000162434 JAK1 801223 sc-eQTL 6.11e-01 -0.033 0.0648 0.445 NK_HLA L2
ENSG00000184588 PDE4B 76463 sc-eQTL 1.38e-01 0.117 0.0785 0.445 NK_HLA L2
ENSG00000213625 LEPROT 448390 sc-eQTL 1.81e-01 -0.134 0.1 0.445 NK_HLA L2
ENSG00000116678 LEPR 448325 sc-eQTL 1.57e-01 -0.128 0.09 0.446 NK_cytokine L2
ENSG00000162434 JAK1 801223 sc-eQTL 1.12e-01 -0.0836 0.0523 0.446 NK_cytokine L2
ENSG00000184588 PDE4B 76463 sc-eQTL 7.08e-01 0.0309 0.0826 0.446 NK_cytokine L2
ENSG00000213625 LEPROT 448390 sc-eQTL 2.22e-01 -0.117 0.0954 0.446 NK_cytokine L2
ENSG00000162434 JAK1 801223 sc-eQTL 2.63e-01 -0.0901 0.0801 0.419 PB L2
ENSG00000184588 PDE4B 76463 sc-eQTL 1.76e-01 -0.138 0.101 0.419 PB L2
ENSG00000213625 LEPROT 448390 sc-eQTL 4.52e-02 -0.224 0.111 0.419 PB L2
ENSG00000162434 JAK1 801223 sc-eQTL 3.97e-01 0.0512 0.0604 0.452 Pro_T L2
ENSG00000184588 PDE4B 76463 sc-eQTL 4.07e-01 -0.0616 0.0741 0.452 Pro_T L2
ENSG00000213625 LEPROT 448390 sc-eQTL 3.42e-01 -0.0893 0.0939 0.452 Pro_T L2
ENSG00000162434 JAK1 801223 sc-eQTL 6.01e-02 -0.143 0.0755 0.447 Treg L2
ENSG00000184588 PDE4B 76463 sc-eQTL 5.94e-01 -0.037 0.0694 0.447 Treg L2
ENSG00000213625 LEPROT 448390 sc-eQTL 5.05e-03 -0.275 0.0969 0.447 Treg L2
ENSG00000116678 LEPR 448325 sc-eQTL 3.87e-01 -0.0811 0.0936 0.444 cDC L2
ENSG00000162433 AK4 721428 sc-eQTL 9.34e-01 -0.00682 0.0829 0.444 cDC L2
ENSG00000162434 JAK1 801223 sc-eQTL 3.06e-01 -0.0792 0.0771 0.444 cDC L2
ENSG00000184588 PDE4B 76463 sc-eQTL 9.99e-01 -6.42e-05 0.0519 0.444 cDC L2
ENSG00000213625 LEPROT 448390 sc-eQTL 8.84e-01 -0.0137 0.0943 0.444 cDC L2
ENSG00000285079 AL513493.1 165015 sc-eQTL 2.91e-01 0.0358 0.0338 0.444 cDC L2
ENSG00000116678 LEPR 448325 sc-eQTL 5.52e-01 0.0537 0.0901 0.447 cMono_IL1B L2
ENSG00000162433 AK4 721428 sc-eQTL 8.86e-01 -0.0119 0.083 0.447 cMono_IL1B L2
ENSG00000162434 JAK1 801223 sc-eQTL 1.14e-01 -0.119 0.075 0.447 cMono_IL1B L2
ENSG00000184588 PDE4B 76463 sc-eQTL 8.42e-01 0.00836 0.0418 0.447 cMono_IL1B L2
ENSG00000213625 LEPROT 448390 sc-eQTL 1.65e-01 -0.0846 0.0607 0.447 cMono_IL1B L2
ENSG00000116678 LEPR 448325 sc-eQTL 3.29e-01 0.086 0.088 0.447 cMono_S100A L2
ENSG00000162433 AK4 721428 sc-eQTL 2.32e-01 0.1 0.0834 0.447 cMono_S100A L2
ENSG00000162434 JAK1 801223 sc-eQTL 8.70e-01 0.0127 0.0772 0.447 cMono_S100A L2
ENSG00000184588 PDE4B 76463 sc-eQTL 8.60e-01 0.00773 0.0437 0.447 cMono_S100A L2
ENSG00000213625 LEPROT 448390 sc-eQTL 7.13e-02 -0.13 0.0717 0.447 cMono_S100A L2
ENSG00000162434 JAK1 801223 sc-eQTL 5.99e-02 -0.209 0.11 0.464 gdT L2
ENSG00000184588 PDE4B 76463 sc-eQTL 9.44e-01 0.00459 0.0649 0.464 gdT L2
ENSG00000213625 LEPROT 448390 sc-eQTL 9.86e-01 -0.0021 0.118 0.464 gdT L2
ENSG00000116678 LEPR 448325 sc-eQTL 6.86e-01 -0.0363 0.0897 0.44 intMono L2
ENSG00000162433 AK4 721428 sc-eQTL 5.14e-02 0.164 0.0837 0.44 intMono L2
ENSG00000162434 JAK1 801223 sc-eQTL 3.80e-01 -0.0687 0.078 0.44 intMono L2
ENSG00000184588 PDE4B 76463 sc-eQTL 9.81e-02 -0.0745 0.0448 0.44 intMono L2
ENSG00000213625 LEPROT 448390 sc-eQTL 8.68e-01 0.0125 0.0753 0.44 intMono L2
ENSG00000116678 LEPR 448325 sc-eQTL 5.74e-01 0.0498 0.0885 0.45 ncMono L2
ENSG00000162433 AK4 721428 sc-eQTL 5.93e-01 -0.0423 0.0789 0.45 ncMono L2
ENSG00000162434 JAK1 801223 sc-eQTL 1.30e-01 -0.0967 0.0635 0.45 ncMono L2
ENSG00000184588 PDE4B 76463 sc-eQTL 6.00e-01 0.0266 0.0507 0.45 ncMono L2
ENSG00000213625 LEPROT 448390 sc-eQTL 6.11e-01 -0.0462 0.0906 0.45 ncMono L2
ENSG00000116678 LEPR 448325 sc-eQTL 2.13e-01 0.12 0.0958 0.432 pDC L2
ENSG00000162433 AK4 721428 sc-eQTL 5.98e-01 0.0332 0.0627 0.432 pDC L2
ENSG00000162434 JAK1 801223 sc-eQTL 5.99e-01 -0.0442 0.0838 0.432 pDC L2
ENSG00000184588 PDE4B 76463 sc-eQTL 3.59e-01 -0.0672 0.073 0.432 pDC L2
ENSG00000213625 LEPROT 448390 sc-eQTL 9.96e-01 0.000528 0.104 0.432 pDC L2
ENSG00000285079 AL513493.1 165015 sc-eQTL 8.04e-01 0.0195 0.0785 0.432 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 801223 sc-eQTL 9.42e-02 -0.117 0.0694 0.447 B_Memory LOneK1K
ENSG00000184588 PDE4B 76463 sc-eQTL 3.55e-01 -0.0531 0.0573 0.447 B_Memory LOneK1K
ENSG00000213625 LEPROT 448390 sc-eQTL 6.61e-03 -0.242 0.0882 0.447 B_Memory LOneK1K
ENSG00000162434 JAK1 801223 sc-eQTL 7.55e-01 -0.0218 0.0698 0.447 B_Naive LOneK1K
ENSG00000184588 PDE4B 76463 sc-eQTL 7.20e-01 -0.0225 0.0627 0.447 B_Naive LOneK1K
ENSG00000213625 LEPROT 448390 sc-eQTL 4.71e-01 -0.0636 0.0881 0.447 B_Naive LOneK1K
ENSG00000116678 LEPR 448325 sc-eQTL 3.90e-01 0.0758 0.088 0.447 CD14_Mono LOneK1K
ENSG00000162433 AK4 721428 sc-eQTL 3.34e-01 0.0815 0.0842 0.447 CD14_Mono LOneK1K
ENSG00000162434 JAK1 801223 sc-eQTL 4.26e-01 -0.0563 0.0705 0.447 CD14_Mono LOneK1K
ENSG00000184588 PDE4B 76463 sc-eQTL 8.87e-01 -0.00513 0.036 0.447 CD14_Mono LOneK1K
ENSG00000213625 LEPROT 448390 sc-eQTL 5.20e-02 -0.115 0.0587 0.447 CD14_Mono LOneK1K
ENSG00000116678 LEPR 448325 sc-eQTL 9.15e-01 -0.00956 0.0894 0.446 CD16_Mono LOneK1K
ENSG00000162433 AK4 721428 sc-eQTL 3.25e-01 0.0798 0.0808 0.446 CD16_Mono LOneK1K
ENSG00000162434 JAK1 801223 sc-eQTL 5.59e-02 -0.104 0.054 0.446 CD16_Mono LOneK1K
ENSG00000184588 PDE4B 76463 sc-eQTL 8.11e-01 -0.00997 0.0416 0.446 CD16_Mono LOneK1K
ENSG00000213625 LEPROT 448390 sc-eQTL 9.36e-01 0.00613 0.076 0.446 CD16_Mono LOneK1K
ENSG00000116678 LEPR 448325 sc-eQTL 9.50e-02 -0.154 0.0918 0.446 NK_CD56dim LOneK1K
ENSG00000162434 JAK1 801223 sc-eQTL 2.52e-02 -0.0965 0.0428 0.446 NK_CD56dim LOneK1K
ENSG00000184588 PDE4B 76463 sc-eQTL 8.06e-02 0.117 0.0667 0.446 NK_CD56dim LOneK1K
ENSG00000213625 LEPROT 448390 sc-eQTL 2.14e-01 -0.119 0.0955 0.446 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000162433 AK4 721428 eQTL 0.0425 0.0457 0.0225 0.00302 0.0 0.447
ENSG00000226891 LINC01359 866488 eQTL 0.0197 -0.067 0.0287 0.00226 0.0 0.447

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000116675 \N 620758 6.97e-07 3.11e-07 1.07e-07 2.66e-07 1.1e-07 1.71e-07 4.42e-07 1.4e-07 3.94e-07 2.28e-07 4.3e-07 3.3e-07 5.39e-07 1.07e-07 1.45e-07 2.08e-07 2.07e-07 3.44e-07 2.12e-07 1.24e-07 1.91e-07 3.13e-07 3.03e-07 1.15e-07 4.67e-07 2.68e-07 2.52e-07 1.86e-07 2.78e-07 2.89e-07 1.93e-07 7.71e-08 5.75e-08 1.57e-07 1.95e-07 9.51e-08 1.05e-07 7.66e-08 4.37e-08 5.64e-08 5.19e-08 2.71e-07 1.65e-08 1.09e-08 8.06e-08 1.78e-08 7.89e-08 3.2e-09 5.35e-08
ENSG00000116678 \N 448325 1.31e-06 8.34e-07 3.02e-07 4.25e-07 1.4e-07 3.12e-07 7.32e-07 3.33e-07 1.08e-06 3.46e-07 1.09e-06 5.77e-07 1.2e-06 2.12e-07 4.01e-07 5.69e-07 7.47e-07 5.26e-07 4.7e-07 4.13e-07 3.07e-07 7.21e-07 5.81e-07 3.93e-07 1.46e-06 3.63e-07 5.83e-07 4.11e-07 7.07e-07 8.51e-07 4.32e-07 3.72e-08 1.05e-07 4.57e-07 3.26e-07 3.71e-07 4.21e-07 1.41e-07 1.34e-07 9.5e-09 1.85e-07 7.53e-07 6.68e-08 1.87e-08 1.93e-07 6.01e-08 1.76e-07 8.34e-08 6.27e-08