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Genes within 1Mb (chr1:65845006:A:C):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 777252 sc-eQTL 7.17e-02 -0.101 0.0558 0.333 B L1
ENSG00000184588 PDE4B 52492 sc-eQTL 6.07e-01 -0.0302 0.0587 0.333 B L1
ENSG00000213625 LEPROT 424419 sc-eQTL 5.32e-01 0.0449 0.0718 0.333 B L1
ENSG00000162434 JAK1 777252 sc-eQTL 3.28e-01 -0.0535 0.0547 0.333 CD4T L1
ENSG00000184588 PDE4B 52492 sc-eQTL 9.54e-01 -0.00381 0.0653 0.333 CD4T L1
ENSG00000213625 LEPROT 424419 sc-eQTL 3.61e-01 0.0782 0.0855 0.333 CD4T L1
ENSG00000116678 LEPR 424354 sc-eQTL 3.90e-01 -0.0806 0.0935 0.333 CD8T L1
ENSG00000162434 JAK1 777252 sc-eQTL 8.71e-01 0.0118 0.0726 0.333 CD8T L1
ENSG00000184588 PDE4B 52492 sc-eQTL 7.28e-01 0.0216 0.0619 0.333 CD8T L1
ENSG00000213625 LEPROT 424419 sc-eQTL 2.98e-01 0.1 0.096 0.333 CD8T L1
ENSG00000116678 LEPR 424354 sc-eQTL 1.10e-01 0.147 0.0919 0.333 DC L1
ENSG00000162433 AK4 697457 sc-eQTL 6.02e-01 -0.0406 0.0777 0.333 DC L1
ENSG00000162434 JAK1 777252 sc-eQTL 8.12e-01 0.0154 0.0647 0.333 DC L1
ENSG00000184588 PDE4B 52492 sc-eQTL 8.83e-01 -0.00736 0.0501 0.333 DC L1
ENSG00000213625 LEPROT 424419 sc-eQTL 2.64e-01 0.102 0.0914 0.333 DC L1
ENSG00000285079 AL513493.1 141044 sc-eQTL 5.78e-01 -0.0275 0.0493 0.333 DC L1
ENSG00000116678 LEPR 424354 sc-eQTL 2.21e-01 0.111 0.0906 0.333 Mono L1
ENSG00000162433 AK4 697457 sc-eQTL 5.01e-01 0.056 0.0831 0.333 Mono L1
ENSG00000162434 JAK1 777252 sc-eQTL 1.03e-01 -0.0965 0.059 0.333 Mono L1
ENSG00000184588 PDE4B 52492 sc-eQTL 2.03e-01 0.0418 0.0327 0.333 Mono L1
ENSG00000213625 LEPROT 424419 sc-eQTL 6.95e-01 -0.023 0.0587 0.333 Mono L1
ENSG00000116678 LEPR 424354 sc-eQTL 2.04e-02 0.206 0.088 0.333 NK L1
ENSG00000162434 JAK1 777252 sc-eQTL 9.72e-01 0.00148 0.0421 0.333 NK L1
ENSG00000184588 PDE4B 52492 sc-eQTL 7.89e-02 0.101 0.057 0.333 NK L1
ENSG00000213625 LEPROT 424419 sc-eQTL 3.87e-01 0.0831 0.0959 0.333 NK L1
ENSG00000162434 JAK1 777252 sc-eQTL 1.89e-01 -0.0799 0.0606 0.333 Other_T L1
ENSG00000184588 PDE4B 52492 sc-eQTL 3.43e-02 0.139 0.0654 0.333 Other_T L1
ENSG00000213625 LEPROT 424419 sc-eQTL 8.97e-01 -0.0123 0.0956 0.333 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 777252 sc-eQTL 8.40e-01 -0.0194 0.0963 0.332 B_Activated L2
ENSG00000184588 PDE4B 52492 sc-eQTL 8.49e-01 -0.0146 0.0764 0.332 B_Activated L2
ENSG00000213625 LEPROT 424419 sc-eQTL 4.95e-01 0.0688 0.101 0.332 B_Activated L2
ENSG00000162434 JAK1 777252 sc-eQTL 4.30e-01 -0.0627 0.0794 0.333 B_Intermediate L2
ENSG00000184588 PDE4B 52492 sc-eQTL 6.46e-01 -0.0298 0.0647 0.333 B_Intermediate L2
ENSG00000213625 LEPROT 424419 sc-eQTL 1.32e-01 -0.14 0.0927 0.333 B_Intermediate L2
ENSG00000162434 JAK1 777252 sc-eQTL 3.02e-02 -0.173 0.0793 0.336 B_Memory L2
ENSG00000184588 PDE4B 52492 sc-eQTL 6.89e-01 0.0329 0.0819 0.336 B_Memory L2
ENSG00000213625 LEPROT 424419 sc-eQTL 9.74e-01 0.00306 0.0932 0.336 B_Memory L2
ENSG00000162434 JAK1 777252 sc-eQTL 4.42e-01 -0.0554 0.072 0.333 B_Naive1 L2
ENSG00000184588 PDE4B 52492 sc-eQTL 7.44e-01 -0.0227 0.0695 0.333 B_Naive1 L2
ENSG00000213625 LEPROT 424419 sc-eQTL 9.27e-01 0.00864 0.094 0.333 B_Naive1 L2
ENSG00000162434 JAK1 777252 sc-eQTL 3.06e-01 -0.0775 0.0756 0.335 B_Naive2 L2
ENSG00000184588 PDE4B 52492 sc-eQTL 7.74e-01 0.0172 0.0599 0.335 B_Naive2 L2
ENSG00000213625 LEPROT 424419 sc-eQTL 2.38e-01 0.108 0.091 0.335 B_Naive2 L2
ENSG00000162434 JAK1 777252 sc-eQTL 2.98e-01 0.0923 0.0886 0.327 CD4_CTL L2
ENSG00000184588 PDE4B 52492 sc-eQTL 6.87e-02 -0.143 0.0779 0.327 CD4_CTL L2
ENSG00000213625 LEPROT 424419 sc-eQTL 2.78e-01 0.111 0.102 0.327 CD4_CTL L2
ENSG00000162434 JAK1 777252 sc-eQTL 4.79e-01 -0.0379 0.0535 0.333 CD4_Naive L2
ENSG00000184588 PDE4B 52492 sc-eQTL 5.40e-01 0.0412 0.067 0.333 CD4_Naive L2
ENSG00000213625 LEPROT 424419 sc-eQTL 1.64e-01 0.121 0.0865 0.333 CD4_Naive L2
ENSG00000162434 JAK1 777252 sc-eQTL 2.71e-01 -0.0671 0.0608 0.333 CD4_TCM L2
ENSG00000184588 PDE4B 52492 sc-eQTL 4.04e-01 -0.0583 0.0697 0.333 CD4_TCM L2
ENSG00000213625 LEPROT 424419 sc-eQTL 3.20e-01 -0.0879 0.0882 0.333 CD4_TCM L2
ENSG00000162434 JAK1 777252 sc-eQTL 2.76e-01 -0.089 0.0815 0.333 CD4_TEM L2
ENSG00000184588 PDE4B 52492 sc-eQTL 9.56e-01 0.00418 0.0755 0.333 CD4_TEM L2
ENSG00000213625 LEPROT 424419 sc-eQTL 8.17e-01 0.0224 0.097 0.333 CD4_TEM L2
ENSG00000116678 LEPR 424354 sc-eQTL 8.19e-02 -0.158 0.0904 0.333 CD8_CTL L2
ENSG00000162434 JAK1 777252 sc-eQTL 9.59e-01 -0.00398 0.0765 0.333 CD8_CTL L2
ENSG00000184588 PDE4B 52492 sc-eQTL 6.46e-01 0.0325 0.0707 0.333 CD8_CTL L2
ENSG00000213625 LEPROT 424419 sc-eQTL 8.67e-01 -0.0157 0.0935 0.333 CD8_CTL L2
ENSG00000116678 LEPR 424354 sc-eQTL 4.21e-01 -0.0734 0.091 0.333 CD8_Naive L2
ENSG00000162434 JAK1 777252 sc-eQTL 2.86e-01 -0.081 0.0757 0.333 CD8_Naive L2
ENSG00000184588 PDE4B 52492 sc-eQTL 5.01e-01 0.043 0.0638 0.333 CD8_Naive L2
ENSG00000213625 LEPROT 424419 sc-eQTL 3.18e-01 0.0929 0.0928 0.333 CD8_Naive L2
ENSG00000116678 LEPR 424354 sc-eQTL 9.63e-02 -0.152 0.0911 0.333 CD8_TCM L2
ENSG00000162434 JAK1 777252 sc-eQTL 5.43e-01 -0.0486 0.0796 0.333 CD8_TCM L2
ENSG00000184588 PDE4B 52492 sc-eQTL 3.48e-01 -0.0822 0.0875 0.333 CD8_TCM L2
ENSG00000213625 LEPROT 424419 sc-eQTL 7.65e-01 0.0298 0.0994 0.333 CD8_TCM L2
ENSG00000116678 LEPR 424354 sc-eQTL 7.39e-01 0.0281 0.0842 0.331 CD8_TEM L2
ENSG00000162434 JAK1 777252 sc-eQTL 5.65e-01 -0.0549 0.0952 0.331 CD8_TEM L2
ENSG00000184588 PDE4B 52492 sc-eQTL 7.50e-01 0.0259 0.081 0.331 CD8_TEM L2
ENSG00000213625 LEPROT 424419 sc-eQTL 3.14e-01 0.0988 0.0979 0.331 CD8_TEM L2
ENSG00000162434 JAK1 777252 sc-eQTL 8.78e-01 -0.013 0.0847 0.333 MAIT L2
ENSG00000184588 PDE4B 52492 sc-eQTL 8.41e-02 0.125 0.0719 0.333 MAIT L2
ENSG00000213625 LEPROT 424419 sc-eQTL 1.03e-01 -0.159 0.0969 0.333 MAIT L2
ENSG00000116678 LEPR 424354 sc-eQTL 4.00e-01 0.0739 0.0876 0.338 NK_CD56bright L2
ENSG00000162434 JAK1 777252 sc-eQTL 5.01e-01 -0.0405 0.06 0.338 NK_CD56bright L2
ENSG00000184588 PDE4B 52492 sc-eQTL 4.43e-02 0.145 0.0714 0.338 NK_CD56bright L2
ENSG00000213625 LEPROT 424419 sc-eQTL 1.52e-01 0.141 0.0982 0.338 NK_CD56bright L2
ENSG00000116678 LEPR 424354 sc-eQTL 1.27e-01 0.143 0.0937 0.332 NK_CD56dim L2
ENSG00000162434 JAK1 777252 sc-eQTL 7.42e-01 -0.0162 0.0492 0.332 NK_CD56dim L2
ENSG00000184588 PDE4B 52492 sc-eQTL 1.48e-01 0.104 0.0715 0.332 NK_CD56dim L2
ENSG00000213625 LEPROT 424419 sc-eQTL 9.39e-01 -0.00759 0.0995 0.332 NK_CD56dim L2
ENSG00000116678 LEPR 424354 sc-eQTL 4.84e-01 0.0578 0.0824 0.342 NK_HLA L2
ENSG00000162434 JAK1 777252 sc-eQTL 6.31e-01 0.0309 0.0642 0.342 NK_HLA L2
ENSG00000184588 PDE4B 52492 sc-eQTL 8.68e-01 0.013 0.0782 0.342 NK_HLA L2
ENSG00000213625 LEPROT 424419 sc-eQTL 4.63e-01 0.0732 0.0994 0.342 NK_HLA L2
ENSG00000116678 LEPR 424354 sc-eQTL 1.15e-01 0.143 0.0906 0.332 NK_cytokine L2
ENSG00000162434 JAK1 777252 sc-eQTL 9.66e-01 0.00225 0.0531 0.332 NK_cytokine L2
ENSG00000184588 PDE4B 52492 sc-eQTL 5.18e-02 0.161 0.0825 0.332 NK_cytokine L2
ENSG00000213625 LEPROT 424419 sc-eQTL 2.26e-01 0.117 0.0962 0.332 NK_cytokine L2
ENSG00000162434 JAK1 777252 sc-eQTL 4.30e-01 -0.0673 0.0851 0.315 PB L2
ENSG00000184588 PDE4B 52492 sc-eQTL 5.31e-01 0.0679 0.108 0.315 PB L2
ENSG00000213625 LEPROT 424419 sc-eQTL 3.55e-01 0.111 0.119 0.315 PB L2
ENSG00000162434 JAK1 777252 sc-eQTL 2.32e-01 -0.0737 0.0615 0.33 Pro_T L2
ENSG00000184588 PDE4B 52492 sc-eQTL 4.48e-01 0.0575 0.0756 0.33 Pro_T L2
ENSG00000213625 LEPROT 424419 sc-eQTL 1.70e-01 0.132 0.0956 0.33 Pro_T L2
ENSG00000162434 JAK1 777252 sc-eQTL 9.15e-01 0.00823 0.0766 0.333 Treg L2
ENSG00000184588 PDE4B 52492 sc-eQTL 9.10e-01 -0.00788 0.0699 0.333 Treg L2
ENSG00000213625 LEPROT 424419 sc-eQTL 3.13e-01 -0.1 0.0991 0.333 Treg L2
ENSG00000116678 LEPR 424354 sc-eQTL 1.48e-01 0.136 0.0938 0.332 cDC L2
ENSG00000162433 AK4 697457 sc-eQTL 8.26e-01 -0.0184 0.0833 0.332 cDC L2
ENSG00000162434 JAK1 777252 sc-eQTL 7.48e-01 -0.025 0.0778 0.332 cDC L2
ENSG00000184588 PDE4B 52492 sc-eQTL 3.82e-01 -0.0457 0.0521 0.332 cDC L2
ENSG00000213625 LEPROT 424419 sc-eQTL 7.27e-02 0.17 0.094 0.332 cDC L2
ENSG00000285079 AL513493.1 141044 sc-eQTL 1.25e-01 -0.0522 0.0338 0.332 cDC L2
ENSG00000116678 LEPR 424354 sc-eQTL 4.88e-01 0.0634 0.0914 0.333 cMono_IL1B L2
ENSG00000162433 AK4 697457 sc-eQTL 2.03e-01 0.107 0.0839 0.333 cMono_IL1B L2
ENSG00000162434 JAK1 777252 sc-eQTL 6.05e-01 -0.0396 0.0765 0.333 cMono_IL1B L2
ENSG00000184588 PDE4B 52492 sc-eQTL 1.78e-01 0.0572 0.0423 0.333 cMono_IL1B L2
ENSG00000213625 LEPROT 424419 sc-eQTL 3.42e-01 0.0587 0.0617 0.333 cMono_IL1B L2
ENSG00000116678 LEPR 424354 sc-eQTL 7.83e-01 0.0247 0.0895 0.333 cMono_S100A L2
ENSG00000162433 AK4 697457 sc-eQTL 9.18e-01 -0.00879 0.0849 0.333 cMono_S100A L2
ENSG00000162434 JAK1 777252 sc-eQTL 4.92e-01 -0.0539 0.0783 0.333 cMono_S100A L2
ENSG00000184588 PDE4B 52492 sc-eQTL 9.43e-01 0.00318 0.0443 0.333 cMono_S100A L2
ENSG00000213625 LEPROT 424419 sc-eQTL 7.04e-01 -0.0279 0.0733 0.333 cMono_S100A L2
ENSG00000162434 JAK1 777252 sc-eQTL 9.83e-02 -0.179 0.107 0.324 gdT L2
ENSG00000184588 PDE4B 52492 sc-eQTL 3.55e-01 0.0584 0.063 0.324 gdT L2
ENSG00000213625 LEPROT 424419 sc-eQTL 8.24e-01 0.0255 0.114 0.324 gdT L2
ENSG00000116678 LEPR 424354 sc-eQTL 6.05e-01 0.0464 0.0895 0.336 intMono L2
ENSG00000162433 AK4 697457 sc-eQTL 3.78e-01 -0.0743 0.0842 0.336 intMono L2
ENSG00000162434 JAK1 777252 sc-eQTL 8.63e-02 -0.133 0.0774 0.336 intMono L2
ENSG00000184588 PDE4B 52492 sc-eQTL 8.59e-01 0.00804 0.0451 0.336 intMono L2
ENSG00000213625 LEPROT 424419 sc-eQTL 2.09e-01 -0.0944 0.0749 0.336 intMono L2
ENSG00000116678 LEPR 424354 sc-eQTL 4.34e-01 0.0682 0.087 0.335 ncMono L2
ENSG00000162433 AK4 697457 sc-eQTL 4.44e-01 0.0595 0.0776 0.335 ncMono L2
ENSG00000162434 JAK1 777252 sc-eQTL 9.80e-02 -0.104 0.0625 0.335 ncMono L2
ENSG00000184588 PDE4B 52492 sc-eQTL 7.18e-01 -0.0181 0.0499 0.335 ncMono L2
ENSG00000213625 LEPROT 424419 sc-eQTL 8.45e-01 -0.0175 0.0892 0.335 ncMono L2
ENSG00000116678 LEPR 424354 sc-eQTL 6.22e-01 0.0464 0.0939 0.336 pDC L2
ENSG00000162433 AK4 697457 sc-eQTL 3.43e-01 -0.0581 0.0611 0.336 pDC L2
ENSG00000162434 JAK1 777252 sc-eQTL 9.53e-01 0.00482 0.0818 0.336 pDC L2
ENSG00000184588 PDE4B 52492 sc-eQTL 2.81e-01 0.077 0.0711 0.336 pDC L2
ENSG00000213625 LEPROT 424419 sc-eQTL 9.29e-01 -0.00909 0.102 0.336 pDC L2
ENSG00000285079 AL513493.1 141044 sc-eQTL 1.34e-01 -0.115 0.0761 0.336 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000162434 JAK1 777252 sc-eQTL 1.32e-01 -0.106 0.0701 0.333 B_Memory LOneK1K
ENSG00000184588 PDE4B 52492 sc-eQTL 7.91e-01 0.0153 0.0579 0.333 B_Memory LOneK1K
ENSG00000213625 LEPROT 424419 sc-eQTL 6.54e-01 -0.0407 0.0905 0.333 B_Memory LOneK1K
ENSG00000162434 JAK1 777252 sc-eQTL 2.08e-01 -0.0877 0.0694 0.333 B_Naive LOneK1K
ENSG00000184588 PDE4B 52492 sc-eQTL 5.47e-01 -0.0377 0.0625 0.333 B_Naive LOneK1K
ENSG00000213625 LEPROT 424419 sc-eQTL 3.68e-01 0.0793 0.0878 0.333 B_Naive LOneK1K
ENSG00000116678 LEPR 424354 sc-eQTL 5.07e-01 0.0597 0.0897 0.333 CD14_Mono LOneK1K
ENSG00000162433 AK4 697457 sc-eQTL 5.14e-01 0.0561 0.0859 0.333 CD14_Mono LOneK1K
ENSG00000162434 JAK1 777252 sc-eQTL 3.80e-01 -0.0632 0.0718 0.333 CD14_Mono LOneK1K
ENSG00000184588 PDE4B 52492 sc-eQTL 7.83e-01 0.0101 0.0367 0.333 CD14_Mono LOneK1K
ENSG00000213625 LEPROT 424419 sc-eQTL 7.79e-01 0.0169 0.0603 0.333 CD14_Mono LOneK1K
ENSG00000116678 LEPR 424354 sc-eQTL 9.47e-01 0.00603 0.09 0.332 CD16_Mono LOneK1K
ENSG00000162433 AK4 697457 sc-eQTL 7.55e-01 0.0254 0.0815 0.332 CD16_Mono LOneK1K
ENSG00000162434 JAK1 777252 sc-eQTL 5.94e-02 -0.103 0.0544 0.332 CD16_Mono LOneK1K
ENSG00000184588 PDE4B 52492 sc-eQTL 7.81e-01 -0.0117 0.0419 0.332 CD16_Mono LOneK1K
ENSG00000213625 LEPROT 424419 sc-eQTL 2.03e-01 -0.0972 0.0762 0.332 CD16_Mono LOneK1K
ENSG00000116678 LEPR 424354 sc-eQTL 2.02e-02 0.212 0.0907 0.332 NK_CD56dim LOneK1K
ENSG00000162434 JAK1 777252 sc-eQTL 9.69e-01 0.00169 0.0431 0.332 NK_CD56dim LOneK1K
ENSG00000184588 PDE4B 52492 sc-eQTL 1.22e-01 0.103 0.0664 0.332 NK_CD56dim LOneK1K
ENSG00000213625 LEPROT 424419 sc-eQTL 3.78e-01 0.0839 0.0951 0.332 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000116678 LEPR 424354 eQTL 0.00771 0.0605 0.0226 0.0 0.0 0.357

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina