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Genes within 1Mb (chr12:106539486:T:C):

View on , UCSC , GTEx , gnomAD

Immune cell-type specific single cell cis-eQTLs in OASIS
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000008405 CRY1 -554063 sc-eQTL 1.63e-01 -0.0789 0.0563 0.387 B L1
ENSG00000013503 POLR3B 181738 sc-eQTL 7.38e-01 -0.0275 0.082 0.387 B L1
ENSG00000111785 RIC8B -235135 sc-eQTL 1.81e-01 -0.0872 0.065 0.387 B L1
ENSG00000120832 MTERF2 -447674 sc-eQTL 9.09e-01 0.0104 0.0903 0.387 B L1
ENSG00000136026 CKAP4 235207 sc-eQTL 3.84e-01 0.037 0.0423 0.387 B L1
ENSG00000151135 TMEM263 -416233 sc-eQTL 4.30e-01 -0.0501 0.0634 0.387 B L1
ENSG00000166046 TCP11L2 237557 sc-eQTL 6.52e-01 -0.023 0.0509 0.387 B L1
ENSG00000008405 CRY1 -554063 sc-eQTL 5.39e-01 0.0235 0.0382 0.387 CD4T L1
ENSG00000013503 POLR3B 181738 sc-eQTL 2.91e-03 -0.179 0.0596 0.387 CD4T L1
ENSG00000111785 RIC8B -235135 sc-eQTL 9.93e-01 0.000553 0.0599 0.387 CD4T L1
ENSG00000120832 MTERF2 -447674 sc-eQTL 5.16e-01 0.0478 0.0735 0.387 CD4T L1
ENSG00000136026 CKAP4 235207 sc-eQTL 1.14e-06 -0.246 0.0491 0.387 CD4T L1
ENSG00000151135 TMEM263 -416233 sc-eQTL 9.45e-01 0.00401 0.0582 0.387 CD4T L1
ENSG00000151136 BTBD11 -778935 sc-eQTL 9.16e-01 0.00524 0.0499 0.387 CD4T L1
ENSG00000166046 TCP11L2 237557 sc-eQTL 9.77e-04 0.172 0.0515 0.387 CD4T L1
ENSG00000260329 AC007541.1 -416011 sc-eQTL 9.56e-01 0.00466 0.0842 0.387 CD4T L1
ENSG00000008405 CRY1 -554063 sc-eQTL 5.73e-01 -0.0276 0.0488 0.387 CD8T L1
ENSG00000013503 POLR3B 181738 sc-eQTL 4.49e-01 -0.0548 0.0723 0.387 CD8T L1
ENSG00000111785 RIC8B -235135 sc-eQTL 4.12e-01 -0.0598 0.0727 0.387 CD8T L1
ENSG00000120832 MTERF2 -447674 sc-eQTL 3.45e-01 -0.0714 0.0754 0.387 CD8T L1
ENSG00000136026 CKAP4 235207 sc-eQTL 1.02e-01 -0.0781 0.0475 0.387 CD8T L1
ENSG00000151135 TMEM263 -416233 sc-eQTL 4.34e-01 0.0488 0.0622 0.387 CD8T L1
ENSG00000151136 BTBD11 -778935 sc-eQTL 2.32e-01 0.0481 0.0402 0.387 CD8T L1
ENSG00000166046 TCP11L2 237557 sc-eQTL 6.92e-01 0.0168 0.0424 0.387 CD8T L1
ENSG00000260329 AC007541.1 -416011 sc-eQTL 6.69e-01 0.039 0.0911 0.387 CD8T L1
ENSG00000008405 CRY1 -554063 sc-eQTL 4.77e-01 0.0556 0.0781 0.383 DC L1
ENSG00000013503 POLR3B 181738 sc-eQTL 1.94e-01 -0.108 0.083 0.383 DC L1
ENSG00000111785 RIC8B -235135 sc-eQTL 1.02e-01 -0.141 0.0857 0.383 DC L1
ENSG00000120832 MTERF2 -447674 sc-eQTL 5.79e-01 -0.0445 0.0801 0.383 DC L1
ENSG00000136026 CKAP4 235207 sc-eQTL 1.74e-01 -0.078 0.0571 0.383 DC L1
ENSG00000151135 TMEM263 -416233 sc-eQTL 4.76e-01 -0.057 0.0799 0.383 DC L1
ENSG00000151136 BTBD11 -778935 sc-eQTL 8.21e-01 -0.0172 0.0758 0.383 DC L1
ENSG00000166046 TCP11L2 237557 sc-eQTL 5.43e-01 -0.0524 0.0861 0.383 DC L1
ENSG00000008405 CRY1 -554063 sc-eQTL 8.70e-01 -0.00986 0.0603 0.387 Mono L1
ENSG00000013503 POLR3B 181738 sc-eQTL 2.58e-01 0.0818 0.0722 0.387 Mono L1
ENSG00000111785 RIC8B -235135 sc-eQTL 7.53e-01 0.022 0.0695 0.387 Mono L1
ENSG00000136026 CKAP4 235207 sc-eQTL 4.73e-02 -0.103 0.0514 0.387 Mono L1
ENSG00000151136 BTBD11 -778935 sc-eQTL 7.76e-01 -0.019 0.0667 0.387 Mono L1
ENSG00000166046 TCP11L2 237557 sc-eQTL 6.28e-01 0.0292 0.0602 0.387 Mono L1
ENSG00000008405 CRY1 -554063 sc-eQTL 7.72e-01 -0.0125 0.0431 0.388 NK L1
ENSG00000013503 POLR3B 181738 sc-eQTL 5.29e-01 -0.0487 0.0772 0.388 NK L1
ENSG00000074590 NUAK1 399453 sc-eQTL 5.01e-01 0.0513 0.076 0.388 NK L1
ENSG00000111785 RIC8B -235135 sc-eQTL 8.95e-01 0.00949 0.072 0.388 NK L1
ENSG00000120832 MTERF2 -447674 sc-eQTL 8.97e-01 -0.00957 0.0741 0.388 NK L1
ENSG00000136026 CKAP4 235207 sc-eQTL 4.59e-02 -0.138 0.0685 0.388 NK L1
ENSG00000151135 TMEM263 -416233 sc-eQTL 9.66e-01 0.00314 0.0747 0.388 NK L1
ENSG00000151136 BTBD11 -778935 sc-eQTL 6.49e-01 0.0269 0.0591 0.388 NK L1
ENSG00000166046 TCP11L2 237557 sc-eQTL 1.66e-02 0.15 0.0621 0.388 NK L1
ENSG00000260329 AC007541.1 -416011 sc-eQTL 2.45e-01 0.105 0.0896 0.388 NK L1
ENSG00000008405 CRY1 -554063 sc-eQTL 1.81e-01 -0.063 0.047 0.387 Other_T L1
ENSG00000013503 POLR3B 181738 sc-eQTL 8.57e-01 -0.0159 0.0884 0.387 Other_T L1
ENSG00000111785 RIC8B -235135 sc-eQTL 5.52e-01 -0.0369 0.0619 0.387 Other_T L1
ENSG00000120832 MTERF2 -447674 sc-eQTL 5.04e-01 0.0495 0.074 0.387 Other_T L1
ENSG00000136026 CKAP4 235207 sc-eQTL 6.36e-01 0.0263 0.0554 0.387 Other_T L1
ENSG00000151135 TMEM263 -416233 sc-eQTL 3.29e-01 0.0755 0.0772 0.387 Other_T L1
ENSG00000151136 BTBD11 -778935 sc-eQTL 7.59e-01 0.0171 0.0557 0.387 Other_T L1
ENSG00000166046 TCP11L2 237557 sc-eQTL 1.20e-01 0.105 0.0676 0.387 Other_T L1
ENSG00000260329 AC007541.1 -416011 sc-eQTL 3.94e-01 0.0714 0.0836 0.387 Other_T L1
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000008405 CRY1 -554063 sc-eQTL 8.05e-01 0.0229 0.0925 0.375 B_Activated L2
ENSG00000013503 POLR3B 181738 sc-eQTL 1.34e-01 0.136 0.0904 0.375 B_Activated L2
ENSG00000111785 RIC8B -235135 sc-eQTL 2.87e-01 0.0983 0.0921 0.375 B_Activated L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 5.08e-01 -0.0476 0.0717 0.375 B_Activated L2
ENSG00000136026 CKAP4 235207 sc-eQTL 4.18e-01 0.07 0.0863 0.375 B_Activated L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 6.93e-01 0.0381 0.0965 0.375 B_Activated L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 3.36e-01 0.0926 0.0961 0.375 B_Activated L2
ENSG00000008405 CRY1 -554063 sc-eQTL 1.18e-01 -0.134 0.0855 0.386 B_Intermediate L2
ENSG00000013503 POLR3B 181738 sc-eQTL 2.22e-01 -0.116 0.0946 0.386 B_Intermediate L2
ENSG00000111785 RIC8B -235135 sc-eQTL 4.06e-01 -0.0701 0.0841 0.386 B_Intermediate L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 4.23e-02 -0.183 0.0896 0.386 B_Intermediate L2
ENSG00000136026 CKAP4 235207 sc-eQTL 8.13e-01 0.0166 0.0703 0.386 B_Intermediate L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 3.66e-01 -0.0813 0.0898 0.386 B_Intermediate L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 1.94e-01 -0.106 0.0813 0.386 B_Intermediate L2
ENSG00000008405 CRY1 -554063 sc-eQTL 3.39e-01 0.0841 0.0877 0.386 B_Memory L2
ENSG00000013503 POLR3B 181738 sc-eQTL 1.53e-01 -0.132 0.0923 0.386 B_Memory L2
ENSG00000111785 RIC8B -235135 sc-eQTL 1.01e-01 -0.143 0.0868 0.386 B_Memory L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 4.82e-01 -0.0555 0.0787 0.386 B_Memory L2
ENSG00000136026 CKAP4 235207 sc-eQTL 7.60e-01 -0.024 0.0784 0.386 B_Memory L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 8.04e-01 0.0221 0.089 0.386 B_Memory L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 2.27e-01 -0.0942 0.0778 0.386 B_Memory L2
ENSG00000008405 CRY1 -554063 sc-eQTL 6.84e-01 0.0309 0.0756 0.387 B_Naive1 L2
ENSG00000013503 POLR3B 181738 sc-eQTL 4.05e-01 -0.0708 0.0848 0.387 B_Naive1 L2
ENSG00000111785 RIC8B -235135 sc-eQTL 7.36e-01 0.028 0.0829 0.387 B_Naive1 L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 8.42e-01 -0.0182 0.091 0.387 B_Naive1 L2
ENSG00000136026 CKAP4 235207 sc-eQTL 7.98e-01 -0.0164 0.064 0.387 B_Naive1 L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 8.54e-01 -0.0166 0.0901 0.387 B_Naive1 L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 8.48e-01 -0.0121 0.0628 0.387 B_Naive1 L2
ENSG00000008405 CRY1 -554063 sc-eQTL 1.69e-01 -0.125 0.0909 0.384 B_Naive2 L2
ENSG00000013503 POLR3B 181738 sc-eQTL 4.63e-01 0.0675 0.0919 0.384 B_Naive2 L2
ENSG00000111785 RIC8B -235135 sc-eQTL 3.52e-01 -0.0761 0.0816 0.384 B_Naive2 L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 6.81e-01 0.0383 0.0929 0.384 B_Naive2 L2
ENSG00000136026 CKAP4 235207 sc-eQTL 8.68e-01 -0.0133 0.0798 0.384 B_Naive2 L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 3.42e-01 -0.088 0.0924 0.384 B_Naive2 L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 7.05e-01 0.0258 0.068 0.384 B_Naive2 L2
ENSG00000008405 CRY1 -554063 sc-eQTL 4.58e-01 -0.0539 0.0725 0.38 CD4_CTL L2
ENSG00000013503 POLR3B 181738 sc-eQTL 4.62e-01 0.065 0.0881 0.38 CD4_CTL L2
ENSG00000111785 RIC8B -235135 sc-eQTL 7.69e-01 -0.0273 0.0929 0.38 CD4_CTL L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 2.26e-01 0.107 0.0885 0.38 CD4_CTL L2
ENSG00000136026 CKAP4 235207 sc-eQTL 4.47e-01 -0.0555 0.0728 0.38 CD4_CTL L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 5.32e-01 0.059 0.0943 0.38 CD4_CTL L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 2.35e-01 0.088 0.0738 0.38 CD4_CTL L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 4.55e-01 0.0687 0.0919 0.38 CD4_CTL L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 3.28e-01 -0.0774 0.0789 0.38 CD4_CTL L2
ENSG00000008405 CRY1 -554063 sc-eQTL 7.67e-02 0.079 0.0444 0.387 CD4_Naive L2
ENSG00000013503 POLR3B 181738 sc-eQTL 2.32e-02 -0.154 0.0672 0.387 CD4_Naive L2
ENSG00000111785 RIC8B -235135 sc-eQTL 6.55e-01 0.0288 0.0643 0.387 CD4_Naive L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 8.98e-01 0.011 0.0855 0.387 CD4_Naive L2
ENSG00000136026 CKAP4 235207 sc-eQTL 4.14e-04 -0.203 0.0567 0.387 CD4_Naive L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 6.86e-01 -0.0253 0.0626 0.387 CD4_Naive L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 7.46e-01 -0.0182 0.056 0.387 CD4_Naive L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 3.44e-05 0.238 0.0561 0.387 CD4_Naive L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 7.56e-01 0.0274 0.0883 0.387 CD4_Naive L2
ENSG00000008405 CRY1 -554063 sc-eQTL 7.90e-01 0.0149 0.056 0.387 CD4_TCM L2
ENSG00000013503 POLR3B 181738 sc-eQTL 2.70e-01 -0.0849 0.0768 0.387 CD4_TCM L2
ENSG00000111785 RIC8B -235135 sc-eQTL 9.73e-01 0.00274 0.0805 0.387 CD4_TCM L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 7.59e-01 -0.0285 0.0926 0.387 CD4_TCM L2
ENSG00000136026 CKAP4 235207 sc-eQTL 4.29e-03 -0.16 0.0555 0.387 CD4_TCM L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 2.16e-01 -0.0952 0.0768 0.387 CD4_TCM L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 1.97e-01 -0.0806 0.0623 0.387 CD4_TCM L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 3.73e-02 0.129 0.0617 0.387 CD4_TCM L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 6.90e-01 0.0372 0.0934 0.387 CD4_TCM L2
ENSG00000008405 CRY1 -554063 sc-eQTL 6.42e-01 -0.0354 0.0759 0.387 CD4_TEM L2
ENSG00000013503 POLR3B 181738 sc-eQTL 1.25e-01 -0.146 0.0946 0.387 CD4_TEM L2
ENSG00000111785 RIC8B -235135 sc-eQTL 9.52e-01 -0.00529 0.087 0.387 CD4_TEM L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 8.66e-01 0.0157 0.093 0.387 CD4_TEM L2
ENSG00000136026 CKAP4 235207 sc-eQTL 1.91e-02 -0.174 0.0736 0.387 CD4_TEM L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 3.40e-01 0.0817 0.0854 0.387 CD4_TEM L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 1.85e-01 0.0861 0.0647 0.387 CD4_TEM L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 7.88e-02 0.131 0.0741 0.387 CD4_TEM L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 8.81e-01 -0.0135 0.0898 0.387 CD4_TEM L2
ENSG00000008405 CRY1 -554063 sc-eQTL 1.54e-01 -0.0812 0.0567 0.387 CD8_CTL L2
ENSG00000013503 POLR3B 181738 sc-eQTL 5.64e-01 0.0494 0.0856 0.387 CD8_CTL L2
ENSG00000111785 RIC8B -235135 sc-eQTL 1.49e-02 -0.195 0.0794 0.387 CD8_CTL L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 5.24e-02 -0.172 0.0883 0.387 CD8_CTL L2
ENSG00000136026 CKAP4 235207 sc-eQTL 3.31e-01 -0.0742 0.0761 0.387 CD8_CTL L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 1.49e-02 0.178 0.0725 0.387 CD8_CTL L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 3.44e-01 0.075 0.079 0.387 CD8_CTL L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 9.51e-02 0.136 0.0814 0.387 CD8_CTL L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 8.33e-01 -0.0192 0.0908 0.387 CD8_CTL L2
ENSG00000008405 CRY1 -554063 sc-eQTL 6.32e-01 0.0322 0.0671 0.387 CD8_Naive L2
ENSG00000013503 POLR3B 181738 sc-eQTL 7.95e-02 -0.142 0.0808 0.387 CD8_Naive L2
ENSG00000111785 RIC8B -235135 sc-eQTL 1.52e-01 0.124 0.0864 0.387 CD8_Naive L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 7.00e-01 -0.0343 0.089 0.387 CD8_Naive L2
ENSG00000136026 CKAP4 235207 sc-eQTL 4.21e-01 -0.0584 0.0725 0.387 CD8_Naive L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 7.20e-02 -0.139 0.0768 0.387 CD8_Naive L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 2.18e-01 0.0743 0.0601 0.387 CD8_Naive L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 5.45e-01 -0.0393 0.0648 0.387 CD8_Naive L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 4.07e-01 -0.0758 0.0913 0.387 CD8_Naive L2
ENSG00000008405 CRY1 -554063 sc-eQTL 1.32e-01 0.126 0.0833 0.373 CD8_TCM L2
ENSG00000013503 POLR3B 181738 sc-eQTL 6.97e-01 -0.0388 0.0997 0.373 CD8_TCM L2
ENSG00000111785 RIC8B -235135 sc-eQTL 3.60e-01 -0.0876 0.0956 0.373 CD8_TCM L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 3.66e-01 0.0869 0.096 0.373 CD8_TCM L2
ENSG00000136026 CKAP4 235207 sc-eQTL 4.46e-01 -0.0664 0.0869 0.373 CD8_TCM L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 6.21e-01 -0.0492 0.0993 0.373 CD8_TCM L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 8.64e-02 0.143 0.083 0.373 CD8_TCM L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 1.59e-01 -0.118 0.0835 0.373 CD8_TCM L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 2.09e-02 0.209 0.0896 0.373 CD8_TCM L2
ENSG00000008405 CRY1 -554063 sc-eQTL 5.30e-01 0.0523 0.0831 0.393 CD8_TEM L2
ENSG00000013503 POLR3B 181738 sc-eQTL 5.62e-01 -0.0547 0.0943 0.393 CD8_TEM L2
ENSG00000111785 RIC8B -235135 sc-eQTL 7.36e-01 0.0304 0.0901 0.393 CD8_TEM L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 4.16e-01 0.0769 0.0944 0.393 CD8_TEM L2
ENSG00000136026 CKAP4 235207 sc-eQTL 7.45e-01 -0.0282 0.0868 0.393 CD8_TEM L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 9.83e-01 0.00204 0.0949 0.393 CD8_TEM L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 4.79e-01 -0.0616 0.0869 0.393 CD8_TEM L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 5.89e-01 -0.0489 0.0903 0.393 CD8_TEM L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 3.63e-01 -0.0759 0.0833 0.393 CD8_TEM L2
ENSG00000008405 CRY1 -554063 sc-eQTL 4.74e-01 -0.0513 0.0716 0.387 MAIT L2
ENSG00000013503 POLR3B 181738 sc-eQTL 7.35e-01 -0.0306 0.0903 0.387 MAIT L2
ENSG00000111785 RIC8B -235135 sc-eQTL 3.35e-02 -0.17 0.0793 0.387 MAIT L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 3.24e-01 0.0865 0.0875 0.387 MAIT L2
ENSG00000136026 CKAP4 235207 sc-eQTL 3.66e-01 -0.0734 0.0809 0.387 MAIT L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 9.83e-01 -0.00207 0.0948 0.387 MAIT L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 8.44e-01 -0.0142 0.0722 0.387 MAIT L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 1.70e-02 0.196 0.0814 0.387 MAIT L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 8.48e-01 0.017 0.0888 0.387 MAIT L2
ENSG00000008405 CRY1 -554063 sc-eQTL 6.61e-01 0.0303 0.0689 0.396 NK_CD56bright L2
ENSG00000013503 POLR3B 181738 sc-eQTL 5.42e-01 0.0532 0.0871 0.396 NK_CD56bright L2
ENSG00000074590 NUAK1 399453 sc-eQTL 4.09e-02 -0.155 0.0754 0.396 NK_CD56bright L2
ENSG00000111785 RIC8B -235135 sc-eQTL 9.42e-01 0.00687 0.0946 0.396 NK_CD56bright L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 3.87e-02 -0.182 0.0877 0.396 NK_CD56bright L2
ENSG00000136026 CKAP4 235207 sc-eQTL 2.22e-01 -0.0871 0.0711 0.396 NK_CD56bright L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 2.34e-01 0.105 0.0881 0.396 NK_CD56bright L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 7.61e-01 0.0238 0.078 0.396 NK_CD56bright L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 2.43e-01 0.106 0.0908 0.396 NK_CD56bright L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 6.56e-01 0.0389 0.0872 0.396 NK_CD56bright L2
ENSG00000008405 CRY1 -554063 sc-eQTL 3.22e-01 -0.0518 0.0523 0.388 NK_CD56dim L2
ENSG00000013503 POLR3B 181738 sc-eQTL 2.23e-01 -0.0957 0.0784 0.388 NK_CD56dim L2
ENSG00000074590 NUAK1 399453 sc-eQTL 6.82e-01 0.0315 0.0768 0.388 NK_CD56dim L2
ENSG00000111785 RIC8B -235135 sc-eQTL 5.94e-01 0.042 0.0786 0.388 NK_CD56dim L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 9.02e-01 0.00959 0.0782 0.388 NK_CD56dim L2
ENSG00000136026 CKAP4 235207 sc-eQTL 2.20e-01 -0.0966 0.0786 0.388 NK_CD56dim L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 7.52e-01 -0.0258 0.0815 0.388 NK_CD56dim L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 2.44e-01 0.0763 0.0652 0.388 NK_CD56dim L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 1.34e-01 0.103 0.0688 0.388 NK_CD56dim L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 7.05e-01 0.0345 0.091 0.388 NK_CD56dim L2
ENSG00000008405 CRY1 -554063 sc-eQTL 8.78e-01 0.0114 0.0743 0.39 NK_HLA L2
ENSG00000013503 POLR3B 181738 sc-eQTL 7.98e-01 0.0231 0.0899 0.39 NK_HLA L2
ENSG00000074590 NUAK1 399453 sc-eQTL 1.39e-01 0.129 0.0872 0.39 NK_HLA L2
ENSG00000111785 RIC8B -235135 sc-eQTL 1.05e-01 0.149 0.0915 0.39 NK_HLA L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 8.73e-01 -0.0149 0.0932 0.39 NK_HLA L2
ENSG00000136026 CKAP4 235207 sc-eQTL 4.07e-01 -0.0672 0.0808 0.39 NK_HLA L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 2.90e-01 -0.0981 0.0925 0.39 NK_HLA L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 2.01e-02 0.184 0.0784 0.39 NK_HLA L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 6.30e-03 0.247 0.0894 0.39 NK_HLA L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 8.37e-01 -0.0176 0.0853 0.39 NK_HLA L2
ENSG00000008405 CRY1 -554063 sc-eQTL 8.76e-01 -0.00966 0.0616 0.388 NK_cytokine L2
ENSG00000013503 POLR3B 181738 sc-eQTL 8.19e-01 -0.0202 0.0884 0.388 NK_cytokine L2
ENSG00000074590 NUAK1 399453 sc-eQTL 1.35e-01 0.122 0.0812 0.388 NK_cytokine L2
ENSG00000111785 RIC8B -235135 sc-eQTL 2.30e-01 -0.101 0.0835 0.388 NK_cytokine L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 5.99e-01 0.0451 0.0855 0.388 NK_cytokine L2
ENSG00000136026 CKAP4 235207 sc-eQTL 1.56e-01 -0.115 0.0805 0.388 NK_cytokine L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 9.54e-01 0.00508 0.0879 0.388 NK_cytokine L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 7.99e-01 -0.0164 0.0644 0.388 NK_cytokine L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 1.11e-01 0.115 0.0719 0.388 NK_cytokine L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 8.86e-01 0.0129 0.0897 0.388 NK_cytokine L2
ENSG00000008405 CRY1 -554063 sc-eQTL 1.30e-01 -0.148 0.0973 0.385 PB L2
ENSG00000013503 POLR3B 181738 sc-eQTL 1.98e-01 0.136 0.105 0.385 PB L2
ENSG00000111785 RIC8B -235135 sc-eQTL 9.13e-01 -0.0103 0.0945 0.385 PB L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 3.81e-01 -0.078 0.0886 0.385 PB L2
ENSG00000136026 CKAP4 235207 sc-eQTL 4.36e-01 -0.0463 0.0592 0.385 PB L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 7.29e-01 -0.0264 0.0759 0.385 PB L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 7.54e-02 0.175 0.0978 0.385 PB L2
ENSG00000008405 CRY1 -554063 sc-eQTL 3.92e-01 0.0521 0.0607 0.391 Pro_T L2
ENSG00000013503 POLR3B 181738 sc-eQTL 8.87e-01 0.0125 0.0878 0.391 Pro_T L2
ENSG00000111785 RIC8B -235135 sc-eQTL 9.49e-01 0.00527 0.0826 0.391 Pro_T L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 2.50e-01 -0.0952 0.0826 0.391 Pro_T L2
ENSG00000136026 CKAP4 235207 sc-eQTL 4.43e-01 0.0352 0.0458 0.391 Pro_T L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 5.35e-01 -0.0476 0.0766 0.391 Pro_T L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 2.12e-01 0.096 0.0766 0.391 Pro_T L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 3.87e-01 0.0613 0.0706 0.391 Pro_T L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 9.78e-01 -0.00198 0.0732 0.391 Pro_T L2
ENSG00000008405 CRY1 -554063 sc-eQTL 5.94e-01 -0.0409 0.0766 0.387 Treg L2
ENSG00000013503 POLR3B 181738 sc-eQTL 6.88e-01 -0.0365 0.0909 0.387 Treg L2
ENSG00000111785 RIC8B -235135 sc-eQTL 2.60e-01 0.0976 0.0865 0.387 Treg L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 2.96e-01 0.0982 0.0937 0.387 Treg L2
ENSG00000136026 CKAP4 235207 sc-eQTL 1.89e-01 -0.0881 0.0669 0.387 Treg L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 8.03e-01 -0.0218 0.087 0.387 Treg L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 8.02e-01 0.0158 0.0631 0.387 Treg L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 5.31e-03 0.2 0.0711 0.387 Treg L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 3.86e-01 -0.0741 0.0853 0.387 Treg L2
ENSG00000008405 CRY1 -554063 sc-eQTL 3.96e-01 -0.0749 0.088 0.383 cDC L2
ENSG00000013503 POLR3B 181738 sc-eQTL 5.77e-01 -0.0474 0.0847 0.383 cDC L2
ENSG00000111785 RIC8B -235135 sc-eQTL 6.21e-01 -0.0443 0.0895 0.383 cDC L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 8.55e-01 0.0141 0.0771 0.383 cDC L2
ENSG00000136026 CKAP4 235207 sc-eQTL 6.21e-01 -0.0312 0.063 0.383 cDC L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 2.93e-01 -0.0869 0.0823 0.383 cDC L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 9.20e-01 0.00784 0.0777 0.383 cDC L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 2.41e-01 0.11 0.0936 0.383 cDC L2
ENSG00000008405 CRY1 -554063 sc-eQTL 7.45e-01 0.0246 0.0755 0.387 cMono_IL1B L2
ENSG00000013503 POLR3B 181738 sc-eQTL 9.82e-01 -0.00191 0.0854 0.387 cMono_IL1B L2
ENSG00000111785 RIC8B -235135 sc-eQTL 5.04e-01 0.0518 0.0773 0.387 cMono_IL1B L2
ENSG00000136026 CKAP4 235207 sc-eQTL 5.88e-02 -0.11 0.058 0.387 cMono_IL1B L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 9.89e-01 0.000974 0.07 0.387 cMono_IL1B L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 2.43e-01 0.0814 0.0696 0.387 cMono_IL1B L2
ENSG00000008405 CRY1 -554063 sc-eQTL 8.10e-01 0.0212 0.0878 0.387 cMono_S100A L2
ENSG00000013503 POLR3B 181738 sc-eQTL 5.96e-01 -0.0464 0.0875 0.387 cMono_S100A L2
ENSG00000111785 RIC8B -235135 sc-eQTL 7.13e-01 0.0298 0.0809 0.387 cMono_S100A L2
ENSG00000136026 CKAP4 235207 sc-eQTL 7.11e-02 -0.115 0.0635 0.387 cMono_S100A L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 8.32e-01 -0.0171 0.0806 0.387 cMono_S100A L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 3.53e-01 -0.0696 0.0749 0.387 cMono_S100A L2
ENSG00000008405 CRY1 -554063 sc-eQTL 7.28e-01 0.0359 0.103 0.409 gdT L2
ENSG00000013503 POLR3B 181738 sc-eQTL 6.63e-01 -0.0471 0.108 0.409 gdT L2
ENSG00000111785 RIC8B -235135 sc-eQTL 8.77e-02 0.186 0.108 0.409 gdT L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 8.81e-01 -0.0176 0.117 0.409 gdT L2
ENSG00000136026 CKAP4 235207 sc-eQTL 9.48e-01 0.00667 0.103 0.409 gdT L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 9.30e-01 0.00939 0.107 0.409 gdT L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 2.78e-01 0.103 0.0947 0.409 gdT L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 6.62e-01 -0.0489 0.112 0.409 gdT L2
ENSG00000260329 AC007541.1 -416011 sc-eQTL 5.06e-02 0.208 0.105 0.409 gdT L2
ENSG00000008405 CRY1 -554063 sc-eQTL 4.53e-01 -0.066 0.0879 0.393 intMono L2
ENSG00000013503 POLR3B 181738 sc-eQTL 5.89e-01 -0.0462 0.0854 0.393 intMono L2
ENSG00000111785 RIC8B -235135 sc-eQTL 9.15e-01 0.00892 0.0835 0.393 intMono L2
ENSG00000136026 CKAP4 235207 sc-eQTL 1.04e-01 -0.141 0.0865 0.393 intMono L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 9.38e-01 -0.00627 0.0803 0.393 intMono L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 2.53e-01 0.112 0.0974 0.393 intMono L2
ENSG00000008405 CRY1 -554063 sc-eQTL 3.99e-01 -0.0522 0.0618 0.394 ncMono L2
ENSG00000013503 POLR3B 181738 sc-eQTL 1.65e-02 0.19 0.0785 0.394 ncMono L2
ENSG00000111785 RIC8B -235135 sc-eQTL 1.91e-01 0.101 0.077 0.394 ncMono L2
ENSG00000136026 CKAP4 235207 sc-eQTL 8.37e-02 -0.142 0.0819 0.394 ncMono L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 2.80e-01 0.0859 0.0793 0.394 ncMono L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 1.02e-01 0.132 0.0805 0.394 ncMono L2
ENSG00000008405 CRY1 -554063 sc-eQTL 4.83e-01 0.0645 0.0918 0.395 pDC L2
ENSG00000013503 POLR3B 181738 sc-eQTL 1.16e-01 -0.157 0.0995 0.395 pDC L2
ENSG00000111785 RIC8B -235135 sc-eQTL 4.78e-01 -0.0688 0.0967 0.395 pDC L2
ENSG00000120832 MTERF2 -447674 sc-eQTL 2.02e-01 -0.116 0.0902 0.395 pDC L2
ENSG00000136026 CKAP4 235207 sc-eQTL 3.56e-02 -0.134 0.0634 0.395 pDC L2
ENSG00000151135 TMEM263 -416233 sc-eQTL 5.89e-01 0.0555 0.103 0.395 pDC L2
ENSG00000151136 BTBD11 -778935 sc-eQTL 8.23e-01 -0.0179 0.0798 0.395 pDC L2
ENSG00000166046 TCP11L2 237557 sc-eQTL 4.29e-02 -0.195 0.0954 0.395 pDC L2
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
MAF
Cell type
Cluster resolution
ENSG00000008405 CRY1 -554063 sc-eQTL 3.06e-01 -0.0813 0.0793 0.387 B_Memory LOneK1K
ENSG00000013503 POLR3B 181738 sc-eQTL 3.90e-01 -0.0789 0.0916 0.387 B_Memory LOneK1K
ENSG00000111785 RIC8B -235135 sc-eQTL 2.85e-01 -0.0843 0.0786 0.387 B_Memory LOneK1K
ENSG00000120832 MTERF2 -447674 sc-eQTL 4.38e-02 -0.179 0.0883 0.387 B_Memory LOneK1K
ENSG00000136026 CKAP4 235207 sc-eQTL 9.68e-01 0.00247 0.062 0.387 B_Memory LOneK1K
ENSG00000151135 TMEM263 -416233 sc-eQTL 7.99e-01 -0.0222 0.0871 0.387 B_Memory LOneK1K
ENSG00000166046 TCP11L2 237557 sc-eQTL 2.02e-01 -0.0957 0.0748 0.387 B_Memory LOneK1K
ENSG00000008405 CRY1 -554063 sc-eQTL 9.78e-01 -0.00191 0.069 0.387 B_Naive LOneK1K
ENSG00000013503 POLR3B 181738 sc-eQTL 6.38e-01 -0.0407 0.0865 0.387 B_Naive LOneK1K
ENSG00000111785 RIC8B -235135 sc-eQTL 4.45e-01 -0.0647 0.0846 0.387 B_Naive LOneK1K
ENSG00000120832 MTERF2 -447674 sc-eQTL 7.74e-01 0.0266 0.0926 0.387 B_Naive LOneK1K
ENSG00000136026 CKAP4 235207 sc-eQTL 6.82e-01 -0.0264 0.0644 0.387 B_Naive LOneK1K
ENSG00000151135 TMEM263 -416233 sc-eQTL 4.12e-01 -0.0716 0.0872 0.387 B_Naive LOneK1K
ENSG00000166046 TCP11L2 237557 sc-eQTL 7.81e-01 -0.0156 0.0562 0.387 B_Naive LOneK1K
ENSG00000008405 CRY1 -554063 sc-eQTL 4.74e-01 0.052 0.0726 0.387 CD14_Mono LOneK1K
ENSG00000013503 POLR3B 181738 sc-eQTL 8.51e-01 -0.0152 0.0804 0.387 CD14_Mono LOneK1K
ENSG00000111785 RIC8B -235135 sc-eQTL 6.94e-01 0.0293 0.0745 0.387 CD14_Mono LOneK1K
ENSG00000136026 CKAP4 235207 sc-eQTL 2.75e-02 -0.123 0.0553 0.387 CD14_Mono LOneK1K
ENSG00000151136 BTBD11 -778935 sc-eQTL 9.63e-01 0.00313 0.0674 0.387 CD14_Mono LOneK1K
ENSG00000166046 TCP11L2 237557 sc-eQTL 5.93e-01 0.0319 0.0595 0.387 CD14_Mono LOneK1K
ENSG00000008405 CRY1 -554063 sc-eQTL 4.91e-01 -0.0436 0.0631 0.39 CD16_Mono LOneK1K
ENSG00000013503 POLR3B 181738 sc-eQTL 6.71e-02 0.14 0.0763 0.39 CD16_Mono LOneK1K
ENSG00000111785 RIC8B -235135 sc-eQTL 2.05e-01 0.0928 0.073 0.39 CD16_Mono LOneK1K
ENSG00000136026 CKAP4 235207 sc-eQTL 2.84e-02 -0.166 0.075 0.39 CD16_Mono LOneK1K
ENSG00000151136 BTBD11 -778935 sc-eQTL 7.19e-01 0.0264 0.0733 0.39 CD16_Mono LOneK1K
ENSG00000166046 TCP11L2 237557 sc-eQTL 1.51e-01 0.113 0.0782 0.39 CD16_Mono LOneK1K
ENSG00000008405 CRY1 -554063 sc-eQTL 5.31e-01 -0.0275 0.0437 0.388 NK_CD56dim LOneK1K
ENSG00000013503 POLR3B 181738 sc-eQTL 3.91e-01 -0.0682 0.0793 0.388 NK_CD56dim LOneK1K
ENSG00000074590 NUAK1 399453 sc-eQTL 3.60e-01 0.07 0.0763 0.388 NK_CD56dim LOneK1K
ENSG00000111785 RIC8B -235135 sc-eQTL 7.74e-01 0.021 0.0732 0.388 NK_CD56dim LOneK1K
ENSG00000120832 MTERF2 -447674 sc-eQTL 9.85e-01 -0.00143 0.076 0.388 NK_CD56dim LOneK1K
ENSG00000136026 CKAP4 235207 sc-eQTL 9.08e-02 -0.123 0.0722 0.388 NK_CD56dim LOneK1K
ENSG00000151135 TMEM263 -416233 sc-eQTL 7.40e-01 -0.0256 0.0769 0.388 NK_CD56dim LOneK1K
ENSG00000151136 BTBD11 -778935 sc-eQTL 6.38e-01 0.0268 0.0569 0.388 NK_CD56dim LOneK1K
ENSG00000166046 TCP11L2 237557 sc-eQTL 2.02e-02 0.143 0.0613 0.388 NK_CD56dim LOneK1K
ENSG00000260329 AC007541.1 -416011 sc-eQTL 7.63e-01 0.0271 0.0898 0.388 NK_CD56dim LOneK1K

Statistical fine-mapping results from Japan COVID-19 Task Force
(Shown only for PIP>0.001)
Gene ID
Gene Symbol
TSS Distance
Category
P-value
Effect Size
Effect Size (se)
PIP (SuSiE)
PIP (FINEMAP)
MAF
ENSG00000013503 POLR3B 181738 eQTL 4.75e-03 -0.0774 0.0274 0.0 0.0 0.341
ENSG00000074590 NUAK1 399453 eQTL 0.00228 -0.0923 0.0302 0.0 0.0 0.341
ENSG00000120832 MTERF2 -447674 eQTL 0.00944 -0.0624 0.024 0.00315 0.0 0.341
ENSG00000166046 TCP11L2 237557 eQTL 2.33e-19 0.131 0.0143 0.0 0.0 0.341

Expression Modifier Score(EMS) for GTEx 49tissues
Gene ID
Gene Symbol
TSS Distance
Whole Blood
Muscle Skeletal
Liver
Brain Cerebellum
Prostate
Spleen
Skin Sun Exposed Lower leg
Artery Coronary
Esophagus Muscularis
Esophagus Gastroesophageal Junction
Artery Tibial
Heart Atrial Appendage
Nerve Tibial
Heart Left Ventricle
Adrenal Gland
Adipose Visceral Omentum
Pancreas
Lung
Pituitary
Brain Nucleus accumbens basal ganglia
Colon Transverse
Adipose Subcutaneous
Esophagus Mucosa
Brain Cortex
Thyroid
Stomach
Breast Mammary Tissue
Colon Sigmoid
Skin Not Sun Exposed Suprapubic
Testis
Artery Aorta
Brain Amygdala
Brain Anterior cingulate cortex BA24
Brain Caudate basal ganglia
Brain Cerebellar Hemisphere
Brain Frontal Cortex BA9
Brain Hippocampus
Brain Hypothalamus
Brain Putamen basal ganglia
Brain Spinal cord cervical c-1
Brain Substantia nigra
Cells Cultured fibroblasts
Cells EBV-transformed lymphocytes
Kidney Cortex
Minor Salivary Gland
Ovary
Small Intestine Terminal Ileum
Uterus
Vagina
ENSG00000013503 POLR3B 181738 1.39e-06 1.57e-06 2.29e-07 1.22e-06 3.91e-07 6.43e-07 1.23e-06 4.01e-07 1.75e-06 6.28e-07 2.01e-06 9.26e-07 2.67e-06 3.9e-07 4.76e-07 9.51e-07 1.01e-06 1.09e-06 6.6e-07 4.77e-07 7.85e-07 1.87e-06 1.27e-06 5.54e-07 2.34e-06 7.37e-07 1.03e-06 9.24e-07 1.66e-06 1.31e-06 8.43e-07 2.63e-07 2.76e-07 5.87e-07 6.99e-07 4.75e-07 7.15e-07 2.95e-07 4.87e-07 2.42e-07 2.83e-07 2.11e-06 1.22e-07 1.41e-07 2.83e-07 1.35e-07 2.6e-07 9.26e-08 1.91e-07
ENSG00000074590 NUAK1 399453 6.09e-07 3.55e-07 7.72e-08 3.48e-07 1.07e-07 1.44e-07 4.25e-07 7.98e-08 2.6e-07 1.65e-07 4.3e-07 2.28e-07 5.09e-07 9.48e-08 1.26e-07 1.33e-07 1.17e-07 3.04e-07 1.36e-07 8.1e-08 1.59e-07 2.3e-07 2.77e-07 9.63e-08 4.88e-07 2e-07 1.74e-07 1.69e-07 2.31e-07 2.89e-07 1.95e-07 7.59e-08 5.53e-08 1.18e-07 2.58e-07 5.41e-08 6.87e-08 6.2e-08 5.7e-08 5.72e-08 4.32e-08 3.66e-07 3.18e-08 1.8e-08 8.68e-08 8.24e-09 9.34e-08 3.04e-09 5.54e-08
ENSG00000166046 TCP11L2 237557 1.27e-06 9.83e-07 3.06e-07 9.36e-07 2.28e-07 4.63e-07 1.34e-06 3.25e-07 1.15e-06 3.78e-07 1.48e-06 5.98e-07 1.95e-06 2.83e-07 4.35e-07 6.35e-07 8.26e-07 5.47e-07 5.36e-07 6.2e-07 3.61e-07 1.04e-06 8.95e-07 5.75e-07 1.96e-06 2.99e-07 6.16e-07 5.8e-07 1.17e-06 1.2e-06 5.67e-07 1.55e-07 2.33e-07 5.21e-07 5.39e-07 3.94e-07 3.67e-07 1.47e-07 2.19e-07 1.3e-07 3.02e-07 1.49e-06 6.87e-08 5.67e-08 1.84e-07 7.16e-08 1.6e-07 8.37e-08 8.61e-08